{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T02:07:18Z","timestamp":1768788438811,"version":"3.49.0"},"reference-count":43,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2025,4,12]],"date-time":"2025-04-12T00:00:00Z","timestamp":1744416000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: With physiological aging, the pancreas is expected to decrease in size as in every organ. The objective of this study was to examine the correlation between pancreas volume (PV), nutritional status, and glycolyzed hemoglobin A1c (HbA1c) in elderly patients with and without type 2 diabetes mellitus (DM). Materials and Methods: Between July 2020 and April 2022, 109 patients aged \u2265 65 years who applied to geriatrics clinics and outpatient clinics were included in the study. PV was measured from available abdominal contrast-enhanced computed tomography (CT) scans. Patients were divided into two groups according to the presence of DM. The relationship between PV; biochemical parameters, especially HbA1c; and Mini Nutritional Assessment Short Form (MNAsf) score was analyzed between groups. p &lt; 0.05 was considered statistically significant. Results: The mean age of all participants was M: 77.40, with SD: 7.32. A total of 54.1% of the participants were female, and 55 had DM. There were no significant differences in age and gender between those with and without DM. Glucose (p &lt; 0.001), HbA1C (p &lt; 0.001), and triglycerides (p &lt; 0.001) were significantly higher, and HDL (p &lt; 0.001) was significantly lower in patients with DM. PV was also significantly lower in those with DM (p = 0.028). A correlation analysis revealed significant positive correlations between PV, the MNAsf score (rho (109)) = 0.413, p = 0.003), and lipase (rho (109)) = 0.297, p = 0.002). Conclusions: PV, which is expected to decrease with age, was found to be lower in patients with DM in our study in which we evaluated elderly patients with and without DM. We also found that PV was associated with malnutrition. Our study highlights the importance of determining the clinical effects of pancreatic volume in the geriatric population where organ atrophy is expected. Therefore, we believe that more comprehensive studies are needed to clarify the clinical implications of pancreatic volume on our diagnostic and therapeutic decisions.<\/jats:p>","DOI":"10.3390\/medicina61040711","type":"journal-article","created":{"date-parts":[[2025,4,14]],"date-time":"2025-04-14T09:06:51Z","timestamp":1744621611000},"page":"711","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["An Investigation of the Relationship Between Pancreas Volume, Nutritional Status, and HbA1c in Geriatric Patients"],"prefix":"10.3390","volume":"61","author":[{"given":"Mercan","family":"Tastemur","sequence":"first","affiliation":[{"name":"Department of Geriatrics Medicine, Ankara Bilkent City Hospital, Ministry of Health, Ankara 06800, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cagla","family":"Ozdemir","sequence":"additional","affiliation":[{"name":"Evliya \u00c7elebi Training and Research Hospital, K\u00fctahya Health Sciences University, K\u00fctahya 43020, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esin","family":"Olcucuo\u011flu","sequence":"additional","affiliation":[{"name":"Department of Radiology, Ankara Bilkent City Hospital, Ministry of Health, Ankara 06800, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8316-7129","authenticated-orcid":false,"given":"Muhammed Said","family":"Besler","sequence":"additional","affiliation":[{"name":"Department of Radiology, Ankara Bilkent City Hospital, Ministry of Health, Ankara 06800, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0726-0609","authenticated-orcid":false,"given":"Halil","family":"Tekdemir","sequence":"additional","affiliation":[{"name":"Department of Radiology, Ankara Bilkent City Hospital, Ministry of Health, Ankara 06800, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gunes","family":"Arik","sequence":"additional","affiliation":[{"name":"Department of Geriatrics Medicine, Ankara Bilkent City Hospital, Ministry of Health, Ankara 06800, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0384-4957","authenticated-orcid":false,"given":"Kamile","family":"Silay","sequence":"additional","affiliation":[{"name":"Department of Geriatrics Medicine, Ankara Bilkent City Hospital, Ministry of Health, Ankara 06800, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,4,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.1016\/S0140-6736(15)00516-4","article-title":"The World report on ageing and health: A policy framework for healthy ageing","volume":"387","author":"Beard","year":"2016","journal-title":"Lancet"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1093\/geront\/37.4.433","article-title":"Successful aging","volume":"37","author":"Rowe","year":"1997","journal-title":"Gerontologist"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1111\/joim.12745","article-title":"The ageing pancreas: A systematic review of the evidence and analysis of the consequences","volume":"283","author":"Panic","year":"2018","journal-title":"J. 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