{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T02:10:00Z","timestamp":1776132600148,"version":"3.50.1"},"reference-count":14,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T00:00:00Z","timestamp":1744848000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: Dermal matrices have brought solutions for many problems, mainly in the treatment of burns and burn scar revisions. The objective of this study was to draw attention to the limits of a collagen\u2013elastin dermal matrix (MatriDerm\u00ae) in its 1 mm variant for the treatment of burn scars on the face and neck. Materials and Methods: A case series of four patients (three women and one man) with burn scars of the face (one case) and of the neck (three cases) treated with collagen\u2013elastin matrices is presented. In all cases, the excision or release of the scars was performed, and the defects were covered with MatriDerm\u00ae and thin split-thickness skin grafts in the same operative time. Results: In all cases, the graft take was very good but was followed by the important contraction of the graft to such an extent that the results were found to be poor by both the surgeons and the patients. The surface of the new scar was irregular, and the elasticity was low. The article points out some probable causes and draws attention to the need for more objective studies regarding the use of this dermal matrix in burn scars of the head and neck. Conclusions: This collagen\u2013elastin 1 mm dermal matrix should be used with caution for the surgical treatment of burn scars of the head and neck area, and its indication should be carefully weighted.<\/jats:p>","DOI":"10.3390\/medicina61040744","type":"journal-article","created":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T20:50:46Z","timestamp":1744923046000},"page":"744","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["A Collagen\u2013Elastin Regenerative Dermal Matrix May Generate Unfavorable Results in Head and Neck Postburn Scar Reconstruction: A Case Series"],"prefix":"10.3390","volume":"61","author":[{"given":"Bogdan","family":"Nitescu","sequence":"first","affiliation":[{"name":"Faculty of Medicine, University of Medicine and Pharmacy \u201cCarol Davila\u201d, 050474 Bucharest, Romania"},{"name":"Clinical Emergency Hospital of Plastic, Reconstructive Sugery and Burns, 050474 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrei","family":"Dumitrescu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Medicine and Pharmacy \u201cCarol Davila\u201d, 050474 Bucharest, Romania"},{"name":"Clinical Emergency Hospital of Plastic, Reconstructive Sugery and Burns, 050474 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florin Radu","family":"Stanescu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Medicine and Pharmacy \u201cCarol Davila\u201d, 050474 Bucharest, Romania"},{"name":"Clinical Emergency Hospital of Plastic, Reconstructive Sugery and Burns, 050474 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana","family":"Cintacioiu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Medicine and Pharmacy \u201cCarol Davila\u201d, 050474 Bucharest, Romania"},{"name":"Clinical Emergency Hospital of Plastic, Reconstructive Sugery and Burns, 050474 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gratiana","family":"Lates","sequence":"additional","affiliation":[{"name":"Clinical Emergency Hospital of Plastic, Reconstructive Sugery and Burns, 050474 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sorin Viorel","family":"Parasca","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Medicine and Pharmacy \u201cCarol Davila\u201d, 050474 Bucharest, Romania"},{"name":"Clinical Emergency Hospital of Plastic, Reconstructive Sugery and Burns, 050474 Bucharest, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,4,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"100380","DOI":"10.1016\/j.burnso.2024.100380","article-title":"A systematic review of the clinical use of a single-layer bovine collagen-elastin acellular dermal matrix","volume":"9","author":"Hill","year":"2025","journal-title":"Burn. Open"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1093\/jbcr\/irad024","article-title":"A Histological and Clinical Study of MatriDerm\u00ae Use in Burn Reconstruction","volume":"44","author":"Dickson","year":"2023","journal-title":"J. Burn. Care Res."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1111\/wrr.13226","article-title":"Outcomes of dermal substitutes in burns and burn scar reconstruction: A systematic review and meta-analysis","volume":"32","author":"Verwilligen","year":"2024","journal-title":"Wound Repair. Regen."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"35","DOI":"10.20517\/2347-9264.2018.38","article-title":"One-stage reconstruction of neck burns with single-layer dermal matrix","volume":"5","author":"Gaviria","year":"2018","journal-title":"Plast. 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Surg."},{"key":"ref_13","first-page":"e16","article-title":"Neck contracture release with matriderm collagen\/elastin dermal matrix","volume":"11","author":"Greenwood","year":"2011","journal-title":"Eplasty"},{"key":"ref_14","first-page":"49","article-title":"A case-control study evaluating single and dual layer dermal matrix in treating scar contracturesusing theVancouver and POSAS scar scales, and correlations with retraction and function in treating scar contractures","volume":"1","author":"Vana","year":"2025","journal-title":"Regenesis Repair Rehabil."}],"container-title":["Medicina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1648-9144\/61\/4\/744\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T17:16:46Z","timestamp":1760030206000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1648-9144\/61\/4\/744"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,17]]},"references-count":14,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,4]]}},"alternative-id":["medicina61040744"],"URL":"https:\/\/doi.org\/10.3390\/medicina61040744","relation":{},"ISSN":["1648-9144"],"issn-type":[{"value":"1648-9144","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,17]]}}}