{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T04:28:51Z","timestamp":1767155331886,"version":"build-2065373602"},"reference-count":21,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2025,5,17]],"date-time":"2025-05-17T00:00:00Z","timestamp":1747440000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: Chronic wounds severely impair patients\u2019 quality of life (QoL), impacting physical, emotional, and functional well-being. Understanding the multidimensional effects of treatment is key to implementing effective, patient-centered care strategies. This study aimed to assess changes in QoL among patients with chronic wounds using the Dermatology Life Quality Index (DLQI) and EuroQol-5D (EQ-5D), comparing outcomes across treatment modalities. Materials and Methods: A longitudinal observational study was conducted between 2019 and 2024 across three hospitals in the Valencian Community. A total of 278 patients with venous lower-limb ulcers of more than six weeks\u2019 duration were included. Quality-of-life assessments were performed at baseline, one-month follow-up, and discharge. Treatments included alginate, foam, moist wound healing (MWH), compression therapy, and negative-pressure wound therapy (NPWT). Statistical analysis involved Friedman\u2019s test and repeated-measures ANOVA. Results: Significant improvements were observed in overall QoL across most treatment modalities. EQ-5D scores progressively increased, while DLQI scores decreased. Pain, embarrassment, and limitations in daily life (e.g., shopping and social activities) showed marked reductions. MWH and foam demonstrated the most favorable impact on QoL, while NPWT showed more modest improvements, possibly due to patient complexity. Notably, the variable \u201csexuality\u201d remained unchanged (mean = 0.00), possibly due to underreporting or communication barriers. Conclusions: Chronic wound treatments significantly improve patients\u2019 quality of life, particularly in terms of pain and social functioning. The use of combined tools (DLQI and EQ-5D) allows for a more comprehensive understanding of these outcomes. These findings highlight the importance of tailoring wound care to individual needs and addressing psychosocial domains, including sexuality. Community nursing, nutritional support, and long-term follow-up should be incorporated into care plans to optimize results, especially in older adults.<\/jats:p>","DOI":"10.3390\/medicina61050907","type":"journal-article","created":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T08:41:12Z","timestamp":1747730472000},"page":"907","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Longitudinal Observational Study on Quality of Life in Patients with Chronic Wounds Using DLQI and EQ-5D"],"prefix":"10.3390","volume":"61","author":[{"given":"David","family":"Palomar-Albert","sequence":"first","affiliation":[{"name":"Integrity and Skin Care, Integrity and Skin Care Research Group, Catholic University of Valencia SanVicente M\u00e1rtir, 46001 Valencia, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge","family":"Zamora-Ortiz","sequence":"additional","affiliation":[{"name":"Ulcers Unit, Valencia General Hospital Department, 46014 Valencia, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federico","family":"Palomar-Llatas","sequence":"additional","affiliation":[{"name":"Integrity and Skin Care, Integrity and Skin Care Research Group, Catholic University of Valencia SanVicente M\u00e1rtir, 46001 Valencia, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Escudero-Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Integrity and Skin Care, Integrity and Skin Care Research Group, Catholic University of Valencia SanVicente M\u00e1rtir, 46001 Valencia, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alba","family":"Naranjo-Cuellar","sequence":"additional","affiliation":[{"name":"Integrity and Skin Care, Integrity and Skin Care Research Group, Catholic University of Valencia SanVicente M\u00e1rtir, 46001 Valencia, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4849-5922","authenticated-orcid":false,"given":"Maria Isabel","family":"Pastor-Ordu\u00f1a","sequence":"additional","affiliation":[{"name":"Integrity and Skin Care, Integrity and Skin Care Research Group, Catholic University of Valencia SanVicente M\u00e1rtir, 46001 Valencia, Spain"},{"name":"Doctoral School, Catholic University of Valencia San Vicente M\u00e1rtir, 46001 Valencia, Spain"},{"name":"Advanced Nursing Unit in Rheumatology and Rehabilitation, Sagunto Hospital, 46500 Sagunto, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,5,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1111\/iwj.12443","article-title":"Estimating the costs associated with the management of patients with chronic wounds using linked routine data","volume":"13","author":"Phillips","year":"2016","journal-title":"Int. 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