{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T18:48:39Z","timestamp":1791830919497,"version":"4.3.4"},"reference-count":66,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T00:00:00Z","timestamp":1768348800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: Atopic dermatitis and psoriasis are life-long inflammatory diseases affecting more than just the skin. Although their link with mental comorbidities has been established, the role of using self-assessment questionnaires is still debated. The aim of our study was to evaluate differences in the quality of life (DLQI) as well as depression (PHQ-9) and anxiety (GAD-7) questionnaire data and determine their link with individual patient and skin disease factors. Materials and Methods: Demographic, clinical and questionnaire data were collected from Riga 1st hospitals archive. For statistical evaluation, the Mann\u2013Whitney U test and Spearman\u2019s rank correlation coefficient were used. Results: The median DLQI for atopic dermatitis and psoriasis was 10.5 and 10, respectively. The prevalence among women with atopic dermatitis who had a PHQ-9 \u2265 10 was 42.9%, compared to 50.0% in men, and GAD-7 \u2265 10 prevalence was 14.3% and 20.0%, respectively. Psoriatic women had a PHQ-9 \u2265 10 prevalence of 25.0% compared with 28.9% in men. The prevalence of GAD-7 \u2265 10 was 20.0% in females and 15.8% in males. GAD-7 score was elevated in patients with psoriatic genital involvement. Multiple positive correlations were noted between PHQ-9, GAD-7 and DLQI scores. Conclusions: Patient quality of life and prevalence of anxiety and depression symptoms are impacted by psoriasis and atopic dermatitis, with similar patterns observed across genders and comorbidities. Genital involvement could be associated with more severe anxiety symptoms. The correlations between PHQ-9, GAD-7 and DLQI scores indicate that further evaluation might be necessary if quality of life is impaired.<\/jats:p>","DOI":"10.3390\/medicina62010164","type":"journal-article","created":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T09:03:10Z","timestamp":1768381390000},"page":"164","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Depression, Anxiety and Quality of Life in Patients with Atopic Dermatitis and Psoriasis"],"prefix":"10.3390","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-2239-0190","authenticated-orcid":false,"given":"Arina","family":"Arn\u012bte","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venerology, Riga Stradins University, Baznicas Street 18, LV-1010 Riga, Latvia"},{"name":"Riga 1st Hospital, Bruninieku Street 5, LV-1001 Riga, Latvia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0939-8003","authenticated-orcid":false,"given":"Vanda","family":"Bondare-Ansberga","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venerology, Riga Stradins University, Baznicas Street 18, LV-1010 Riga, Latvia"},{"name":"Riga 1st Hospital, Bruninieku Street 5, LV-1001 Riga, Latvia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-8247-1646","authenticated-orcid":false,"given":"Lelde","family":"Reinberga","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venerology, Riga Stradins University, Baznicas Street 18, LV-1010 Riga, Latvia"},{"name":"Riga 1st Hospital, Bruninieku Street 5, LV-1001 Riga, Latvia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5008-9694","authenticated-orcid":false,"given":"Ilona","family":"Hartmane","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venerology, Riga Stradins University, Baznicas Street 18, LV-1010 Riga, Latvia"},{"name":"Riga 1st Hospital, Bruninieku Street 5, LV-1001 Riga, Latvia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4684-0892","authenticated-orcid":false,"given":"Ingm\u0101rs","family":"Mika\u017e\u0101ns","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venerology, Riga Stradins University, Baznicas Street 18, LV-1010 Riga, Latvia"},{"name":"Riga 1st Hospital, Bruninieku Street 5, LV-1001 Riga, Latvia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,1,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1111\/ijd.14864","article-title":"Global burden of psoriasis\u2014Comparison of regional and global epidemiology, 1990 to 2017","volume":"59","author":"AlQassimi","year":"2020","journal-title":"Int. J. Dermatol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1093\/bjd\/ljad339","article-title":"Global epidemiology of atopic dermatitis: A comprehensive systematic analysis and modelling study","volume":"190","author":"Tian","year":"2023","journal-title":"Br. J. Dermatol."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Park, S.Y., and Kim, K.H. (2021). What Factors Influence on Dermatology-Related Life Quality of Psoriasis Patients in South Korea?. Int. J. Environ. Res. Public. Health, 18.","DOI":"10.3390\/ijerph18073624"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.3346\/jkms.2017.32.8.1360","article-title":"Clinical Features of Atopic Dermatitis in Adults Are Different according to Onset","volume":"32","author":"Son","year":"2017","journal-title":"J. Korean Med. Sci."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/978-3-031-54513-9_4","article-title":"Clinical Presentation of Atopic Dermatitis","volume":"1447","author":"Ahn","year":"2024","journal-title":"Adv. Exp. Med. Biol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.anai.2017.10.037","article-title":"The atopic march: Critical evidence and clinical relevance","volume":"120","author":"Hill","year":"2018","journal-title":"Ann. Allergy Asthma Immunol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.anai.2021.02.026","article-title":"Rhinitis prevalence and association with atopic dermatitis: A systematic review and meta-analysis","volume":"127","author":"Knudgaard","year":"2021","journal-title":"Ann. Allergy Asthma Immunol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.jaad.2020.11.037","article-title":"Bidirectional association between atopic dermatitis, conjunctivitis, and other ocular surface diseases: A systematic review and meta-analysis","volume":"85","author":"Ravn","year":"2021","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.ad.2019.03.018","article-title":"Psychosocial Impact of Atopic Dermatitis in Adults: A Qualitative Study. Impacto psicosocial en adultos con dermatitis at\u00f3pica: Estudio cualitativo","volume":"111","author":"Marron","year":"2020","journal-title":"Actas Dermosifiliogr."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"e028116","DOI":"10.1136\/bmjopen-2018-028116","article-title":"Prevalence and characteristics of psoriasis in Denmark: Findings from the Danish skin cohort","volume":"9","author":"Egeberg","year":"2019","journal-title":"BMJ Open"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"adv4591","DOI":"10.2340\/actadv.v103.4591","article-title":"Psoriasis in Norway: A Prescription-based Registry Study of Incidence and Prevalence","volume":"103","author":"Solberg","year":"2023","journal-title":"Acta Derm. Venereol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1016\/j.autrev.2014.01.008","article-title":"Diagnosis and classification of psoriasis","volume":"13","author":"Raychaudhuri","year":"2014","journal-title":"Autoimmun. Rev."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/j.jaad.2017.04.1133","article-title":"Systematic review and meta-analysis of the association between psoriasis and metabolic syndrome","volume":"77","year":"2017","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1111\/1346-8138.15052","article-title":"Increased risk of atherosclerotic cardiovascular disease among patients with psoriasis in Korea: A 15-year nationwide population-based cohort study","volume":"46","author":"Jung","year":"2019","journal-title":"J. Dermatol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"202","DOI":"10.3892\/etm.2020.9332","article-title":"Implications of self-esteem in the quality of life in patients with psoriasis","volume":"20","author":"Brihan","year":"2020","journal-title":"Exp. Ther. Med."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"115078","DOI":"10.1016\/j.psychres.2023.115078","article-title":"Epidemiology of mental health comorbidity in patients with psoriasis: An analysis of trends from 1986 to 2019","volume":"321","author":"Liu","year":"2023","journal-title":"Psychiatry Res."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1111\/j.1468-3083.2010.03705.x","article-title":"Psoriasis: Is the impairment to a patient\u2019s life cumulative?","volume":"24","author":"Kimball","year":"2010","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"342","DOI":"10.5021\/ad.22.035","article-title":"Psychological Stress and Atopic Dermatitis: A Focus Group Study","volume":"35","author":"Abdelhadi","year":"2023","journal-title":"Ann. Dermatol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"300060520961674","DOI":"10.1177\/0300060520961674","article-title":"Efficacy of psychological intervention for patients with psoriasis vulgaris: A prospective study","volume":"48","author":"Li","year":"2020","journal-title":"J. Int. Med. Res."},{"key":"ref_20","first-page":"91","article-title":"Efficacy of Biofeedback and Cognitive-behavioural Therapy in Psoriatic PatientsA Single-blind, Randomized and Controlled Study with Added Narrow-band Ultraviolet B Therapy","volume":"96","author":"Piaserico","year":"2016","journal-title":"Acta Derm. Venereol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1016\/j.jaad.2018.11.057","article-title":"Joint AAD-NPF guidelines of care for the management and treatment of psoriasis with biologics","volume":"80","author":"Menter","year":"2019","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1159\/000250839","article-title":"Severe psoriasis--oral therapy with a new retinoid","volume":"157","author":"Fredriksson","year":"1978","journal-title":"Dermatologica"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1034\/j.1600-0625.2001.100102.x","article-title":"The eczema area and severity index (EASI): Assessment of reliability in atopic dermatitis","volume":"10","author":"Hanifin","year":"2001","journal-title":"EASI Evaluator Group. Exp. Dermatol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1111\/j.1365-2230.1994.tb01167.x","article-title":"Dermatology Life Quality Index (DLQI)\u2014A simple practical measure for routine clinical use","volume":"19","author":"Finlay","year":"1994","journal-title":"Clin. Exp. Dermatol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1046\/j.1525-1497.2001.016009606.x","article-title":"The PHQ-9: Validity of a brief depression severity measure","volume":"16","author":"Kroenke","year":"2001","journal-title":"J. Gen. Intern. Med."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/s12991-018-0203-5","article-title":"Validity of the PHQ-9 and PHQ-2 to screen for depression in nationwide primary care population in Latvia","volume":"17","author":"Rancans","year":"2018","journal-title":"Ann. Gen. Psychiatry"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1001\/archinte.166.10.1092","article-title":"A brief measure for assessing generalized anxiety disorder: The GAD-7","volume":"166","author":"Spitzer","year":"2006","journal-title":"Arch. Intern. Med."},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Vrublevska, J., Renemane, L., Kivite-Urtane, A., and Rancans, E. (2022). Validation of the generalized anxiety disorder scales (GAD-7 and GAD-2) in primary care settings in Latvia. Front. Psychiatry, 13.","DOI":"10.3389\/fpsyt.2022.972628"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.jpsychores.2017.01.010","article-title":"Depression increases the risk of mortality in patients with heart failure: A meta-analysis","volume":"94","author":"Gathright","year":"2017","journal-title":"J. Psychosom. Res."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.genhosppsych.2013.01.006","article-title":"Depression and risk of mortality in individuals with diabetes: A meta-analysis and systematic review","volume":"35","author":"Park","year":"2013","journal-title":"Gen. Hosp. Psychiatry"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"3186","DOI":"10.1038\/s41380-020-00865-6","article-title":"Prognostic value of depression and anxiety on breast cancer recurrence and mortality: A systematic review and meta-analysis of 282,203 patients","volume":"25","author":"Wang","year":"2020","journal-title":"Mol. Psychiatry"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"2243","DOI":"10.1093\/ckj\/sfad127","article-title":"Association between incident depression and clinical outcomes in patients with chronic kidney disease","volume":"16","author":"Zhu","year":"2023","journal-title":"Clin. Kidney J."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1111\/jdv.19686","article-title":"Epidemiology of mental health comorbidity in patients with atopic dermatitis: An analysis of global trends from 1998 to 2022","volume":"38","author":"Cai","year":"2024","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"e889","DOI":"10.1016\/S2468-2667(23)00220-7","article-title":"Prevalence and variability of depressive symptoms in Europe: Update using representative data from the second and third waves of the European Health Interview Survey (EHIS-2 and EHIS-3)","volume":"8","author":"Vilagut","year":"2023","journal-title":"Lancet Public Health"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"S323","DOI":"10.1192\/j.eurpsy.2021.867","article-title":"The results of PHQ-9 screening of latvian general population in 2019\u20132020","volume":"64","author":"Vinogradova","year":"2021","journal-title":"Eur. Psychiatry"},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Vinogradova, V.V., Kivite-Urtane, A., Vrublevska, J., and Rancans, E. (2022). Anxiety Screening among the General Population of Latvia and Associated Factors. Medicina, 58.","DOI":"10.3390\/medicina58091163"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1111\/j.0022-202X.2005.23621.x","article-title":"Translating the science of quality of life into practice: What do dermatology life quality index scores mean?","volume":"125","author":"Hongbo","year":"2005","journal-title":"J. Investig. Dermatol."},{"key":"ref_38","first-page":"195","article-title":"Psoriasis and diabetes: A review of the pathophysiological and therapeutic interconnections","volume":"116","author":"Papara","year":"2025","journal-title":"Minerva Med."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"e2012006","DOI":"10.5620\/eht.2012.27.e2012006","article-title":"The prevalence of atopic dermatitis, asthma, and allergic rhinitis and the comorbidity of allergic diseases in children","volume":"27","author":"Hong","year":"2012","journal-title":"Environ. Health Toxicol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1111\/jdv.19192","article-title":"Depression, a major comorbidity of psoriatic disease, is caused by metabolic inflammation","volume":"37","author":"Mrowietz","year":"2023","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"S\u0103lcudean, A., Popovici, R.-A., Pitic, D.E., S\u00e2rbu, D., Boroghina, A., Jomaa, M., Salehi, M.A., Kher, A.A.M., Lica, M.M., and Bodo, C.R. (2025). Unraveling the Complex Interplay Between Neuroinflammation and Depression: A Comprehensive Review. Int. J. Mol. Sci., 26.","DOI":"10.3390\/ijms26041645"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"e70019","DOI":"10.1111\/apha.70019","article-title":"Proinflammatory cytokines and neuropeptides in psoriasis, depression, and anxiety","volume":"241","author":"Keenan","year":"2025","journal-title":"Acta Physiol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1007\/s40257-017-0274-0","article-title":"Severity of Psoriasis Differs Between Men and Women: A Study of the Clinical Outcome Measure Psoriasis Area and Severity Index (PASI) in 5438 Swedish Register Patients","volume":"18","author":"Eriksson","year":"2017","journal-title":"Am. J. Clin. Dermatol."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.1111\/j.1468-3083.2010.03668.x","article-title":"Gender aspects in skin diseases","volume":"24","author":"Chen","year":"2010","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1001\/jamadermatol.2013.133","article-title":"Access to health care in patients with psoriasis and psoriatic arthritis: Data from National Psoriasis Foundation survey panels","volume":"149","author":"Bhutani","year":"2013","journal-title":"JAMA Dermatol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1111\/j.1365-4632.2008.03485.x","article-title":"\u201cThe Laundry Bag Project\u201d\u2014Unequal distribution of dermatological healthcare resources for male and female psoriatic patients in Sweden","volume":"47","author":"Nyberg","year":"2008","journal-title":"Int. J. Dermatol."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.seizure.2015.07.012","article-title":"Gender differences in depression, but not in anxiety in people with epilepsy","volume":"32","author":"Gaus","year":"2015","journal-title":"Seizure"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"152275","DOI":"10.1016\/j.comppsych.2021.152275","article-title":"Gender differences in prevalence and clinical correlates of anxiety symptoms in first-episode and drug-na\u00efve patients with major depressive disorder","volume":"111","author":"Yang","year":"2021","journal-title":"Compr. Psychiatry"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1111\/j.0022-202X.2004.22703.x","article-title":"Divergent beliefs about psoriasis are associated with increased psychological distress","volume":"123","author":"Richards","year":"2004","journal-title":"J. Investig. Dermatol."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1111\/jdv.14115","article-title":"The impact of age on psoriasis health care in Germany","volume":"31","author":"Trettel","year":"2017","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/S0190-9622(03)02793-2","article-title":"Facial psoriasis: Comparison of patients with and without facial involvement","volume":"50","year":"2004","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_52","first-page":"481","article-title":"Impact of challenging-to-treat areas on quality of life and mental health among plaque psoriasis patients from Sabah, Malaysia","volume":"80","author":"Ong","year":"2025","journal-title":"Med. J. Malays."},{"key":"ref_53","doi-asserted-by":"crossref","unstructured":"Montero-Vilchez, T., Cuenca-Barrales, C., Rodriguez-Pozo, J.A., Diaz-Calvillo, P., Tercedor-Sanchez, J., Martinez-Lopez, A., Molina-Leyva, A., and Arias-Santiago, S. (2022). Epidermal Barrier Function and Skin Homeostasis in Atopic Dermatitis: The Impact of Age. Life, 12.","DOI":"10.3390\/life12010132"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/j.jaad.2022.04.061","article-title":"Longitudinal course and predictors of depressive symptoms in atopic dermatitis","volume":"87","author":"Chatrath","year":"2022","journal-title":"J. Am. Acad. Dermatol."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/j.jaci.2017.01.029","article-title":"Effects of structured patient education in adults with atopic dermatitis: Multicenter randomized controlled trial","volume":"140","author":"Heratizadeh","year":"2017","journal-title":"J. Allergy Clin. Immunol."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1111\/jdv.12301","article-title":"Role of illness representations and coping in patients with atopic dermatitis: A cross-sectional study","volume":"28","author":"Schut","year":"2014","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"e45","DOI":"10.1017\/S204579602100038X","article-title":"Uncovering survivorship bias in longitudinal mental health surveys during the COVID-19 pandemic","volume":"30","author":"Czeisler","year":"2021","journal-title":"Epidemiol. Psychiatr. Sci."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"20329","DOI":"10.2340\/actadv.v104.20329","article-title":"Correlation between Dermatology Life Quality Index and Psoriasis Area and Severity Index in Patients with Psoriasis: A Cross-sectional Global Healthcare Study on Psoriasis","volume":"104","author":"Maul","year":"2024","journal-title":"Acta Derm. Venereol."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"443","DOI":"10.2147\/CCID.S396997","article-title":"Psoriatic Foot Involvement is the Most Significant Contributor to the Inconsistency Between PASI and DLQI: A Retrospective Study from China","volume":"16","author":"Yang","year":"2023","journal-title":"Clin. Cosmet. Investig. Dermatol."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1590\/abd1806-4841.20132052","article-title":"Psoriasis: Correlation between severity index (PASI) and quality of life index (DLQI) in patients assessed before and after systemic treatment","volume":"88","author":"Silva","year":"2013","journal-title":"An. Bras. Dermatol."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1111\/jdv.16966","article-title":"Psoriasis severity: Commonly used clinical thresholds may not adequately convey patient impact","volume":"35","author":"Golbari","year":"2021","journal-title":"J. Eur. Acad. Dermatol. Venereol."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1093\/bjd\/ljad141","article-title":"Electronic screening for mental illness in patients with psoriasis","volume":"189","author":"Bechman","year":"2023","journal-title":"Br. J. Dermatol."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"e70337","DOI":"10.1111\/jocd.70337","article-title":"Exploring Factors, Comorbidities, Quality of Life (DLQI), and Depression (PHQ-9) in Rosacea Patients: A Comprehensive Analysis","volume":"24","author":"Kunwar","year":"2025","journal-title":"J. Cosmet. Dermatol."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"511","DOI":"10.2147\/CCID.S265349","article-title":"Relationship Between Depression and Quality of Life Among Vitiligo Patients: A Self-assessment Questionnaire-based Study","volume":"13","author":"Pruksaeakanan","year":"2020","journal-title":"Clin. Cosmet. Investig. Dermatol."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1111\/ijd.17729","article-title":"Diagnostic Performance of GPT-4o and Gemini Flash 2.0 in Acne and Rosacea","volume":"64","author":"Boostani","year":"2025","journal-title":"Int. J. Dermatol."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"e1052","DOI":"10.1111\/jdv.20861","article-title":"Large language models in evaluating hidradenitis suppurativa from clinical images","volume":"39","author":"Boostani","year":"2025","journal-title":"J. Eur. Acad. Dermatol. Venereol."}],"container-title":["Medicina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1648-9144\/62\/1\/164\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T09:45:55Z","timestamp":1768383955000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1648-9144\/62\/1\/164"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,14]]},"references-count":66,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,1]]}},"alternative-id":["medicina62010164"],"URL":"https:\/\/doi.org\/10.3390\/medicina62010164","relation":{},"ISSN":["1648-9144"],"issn-type":[{"value":"1648-9144","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,14]]}}}