{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T03:52:49Z","timestamp":1790653969639,"version":"4.1.0"},"reference-count":27,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T00:00:00Z","timestamp":1768348800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: Acute mesenteric ischemia (AMI) lacks reliable prognostic biomarkers, and the prognostic performance of the C-reactive protein\u2013albumin\u2013lymphocyte (CALLY) index in this population has not been previously evaluated. This study aimed to assess the predictive value of the CALLY index for 30-day mortality in patients presenting to the emergency department (ED) with AMI. Materials and Methods: This retrospective cohort study included patients aged \u226518 years who presented to the ED with AMI over a 4-year period. Demographic and clinical data were collected. The CALLY index, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and CRP-to-lactate ratio were calculated. The primary outcome was 30-day mortality. Univariate and multivariate logistic regression analyses were performed to identify predictors of mortality. A receiver operating characteristic (ROC) curve analysis was used to assess predictive performance. A p-value &lt; 0.05 was considered statistically significant. Results: A total of 111 patients were included (mean age, 69.2 \u00b1 11.8 years; 52.3% male). The most common comorbidities were hypertension and coronary artery disease (45% each). The 30-day mortality rate was 55.9%. In a univariate analysis, lower CALLY index values were associated with higher mortality (p = 0.011). However, the CALLY index did not remain independently associated with mortality in multivariate logistic regression analysis (p = 0.773). The ROC analysis indicated that the CALLY index had a modest but statistically significant ability to predict 30-day mortality (AUC = 0.64, 95% CI: 0.54\u20130.74, p = 0.011). At a cut-off value of 0.0015, the CALLY index showed a sensitivity of 55% and a specificity of 77%. Conclusions: The CALLY index had modest predictive value for 30-day mortality in patients with AMI.<\/jats:p>","DOI":"10.3390\/medicina62010167","type":"journal-article","created":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T11:01:14Z","timestamp":1768388474000},"page":"167","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The Role of the CALLY Index in 30-Day Mortality Prediction for Acute Mesenteric Ischemia: A Retrospective Cohort Study"],"prefix":"10.3390","volume":"62","author":[{"given":"Yeliz","family":"Simsek","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine, Adana City Research and Training Hospital, Health Science University, 01230 Adana, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akkan","family":"Avci","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Adana City Research and Training Hospital, Health Science University, 01230 Adana, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4639-7130","authenticated-orcid":false,"given":"Ahmet Burak","family":"Urfalioglu","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Adana City Research and Training Hospital, Health Science University, 01230 Adana, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erdem","family":"Aksay","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Adana City Research and Training Hospital, Health Science University, 01230 Adana, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adnan","family":"Kuvvetli","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Adana City Training and Research Hospital, Health Sciences University, 01230 Adana, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramazan","family":"Guven","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Faculty of Medicine, Atlas University Hospital, 34203 Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Begum Seyda","family":"Avci","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Adana City Training and Research Hospital, Health Sciences University, 01230 Adana, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2917-8286","authenticated-orcid":false,"given":"Saliha Dilek","family":"Oztoprak Hacioglu","sequence":"additional","affiliation":[{"name":"Department of Public Health, Adana City Training and Research Hospital, Health Sciences University, 01230 Adana, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1200-9198","authenticated-orcid":false,"given":"Mustafa Oguz","family":"Tugcan","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Faculty of Medicine, Cukurova University, 01330 Adana, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,1,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1177\/08465371221094280","article-title":"An Update on Acute Mesenteric Ischemia","volume":"74","author":"Yu","year":"2023","journal-title":"Can. 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