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Isolated imaging or clinical data may therefore inadequately represent disease-specific pathological characteristics. Materials and Methods: This retrospective study included 605 hip joints from Center A (2018\u20132024), comprising normal hips, osteoarthritis, osteonecrosis of the femoral head (ONFH), and femoroacetabular impingement (FAI). An independent cohort of 24 hips from Center B (2024\u20132025) was used for external validation. A multimodal deep learning framework was developed to jointly analyze radiographs, CT volumes, and clinical texts. Features were extracted using ResNet50, 3D-ResNet50, and a pretrained BERT model, followed by attention-based fusion for four-class classification. Results: The combined Clinical+X-ray+CT model achieved an AUC of 0.949 on the internal test set, outperforming all single-modality models. Improvements were consistently observed in accuracy, sensitivity, specificity, and decision curve analysis. Grad-CAM visualizations confirmed that the model attended to clinically relevant anatomical regions. Conclusions: Attention-based multimodal feature fusion substantially improves diagnostic performance for hip joint diseases, providing an interpretable and clinically applicable framework for early detection and precise classification in orthopedic imaging.<\/jats:p>","DOI":"10.3390\/medicina62020250","type":"journal-article","created":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T10:24:36Z","timestamp":1769423076000},"page":"250","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Intelligent Attention-Driven Deep Learning for Hip Disease Diagnosis: Fusing Multimodal Imaging and Clinical Text for Enhanced Precision and Early Detection"],"prefix":"10.3390","volume":"62","author":[{"given":"Jinming","family":"Zhang","sequence":"first","affiliation":[{"name":"Medical Engineering & Engineering Medicine Innovation Center, Hangzhou International Innovation Institute, Beihang University, Hangzhou 311115, China"},{"name":"Key Laboratory of Biomechanics and Mechanobiology (Beihang University), Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"He","family":"Gong","sequence":"additional","affiliation":[{"name":"Medical Engineering & Engineering Medicine Innovation Center, Hangzhou International Innovation Institute, Beihang University, Hangzhou 311115, China"},{"name":"Key Laboratory of Biomechanics and Mechanobiology (Beihang University), Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pengling","family":"Ren","sequence":"additional","affiliation":[{"name":"Medical Engineering & Engineering Medicine Innovation Center, Hangzhou International Innovation Institute, Beihang University, Hangzhou 311115, China"},{"name":"Key Laboratory of Biomechanics and Mechanobiology (Beihang University), Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuyu","family":"Liu","sequence":"additional","affiliation":[{"name":"Medical Engineering & Engineering Medicine Innovation Center, Hangzhou International Innovation Institute, Beihang University, Hangzhou 311115, China"},{"name":"Key Laboratory of Biomechanics and Mechanobiology (Beihang University), Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengbin","family":"Jia","sequence":"additional","affiliation":[{"name":"Medical Engineering & Engineering Medicine Innovation Center, Hangzhou International Innovation Institute, Beihang University, Hangzhou 311115, China"},{"name":"Key Laboratory of Biomechanics and Mechanobiology (Beihang University), Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lizhen","family":"Wang","sequence":"additional","affiliation":[{"name":"Medical Engineering & Engineering Medicine Innovation Center, Hangzhou International Innovation Institute, Beihang University, Hangzhou 311115, China"},{"name":"Key Laboratory of Biomechanics and Mechanobiology (Beihang University), Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yubo","family":"Fan","sequence":"additional","affiliation":[{"name":"Medical Engineering & Engineering Medicine Innovation Center, Hangzhou International Innovation Institute, Beihang University, Hangzhou 311115, China"},{"name":"Key Laboratory of Biomechanics and Mechanobiology (Beihang University), Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,1,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"rkad070.002","DOI":"10.1093\/rap\/rkad070.002","article-title":"OA02 Hip Pain in the Young and Active Patient? 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