{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T21:06:38Z","timestamp":1788210398688,"version":"build-2803163510"},"reference-count":49,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T00:00:00Z","timestamp":1769385600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: Early assessment interventions are recommended for older adults with sarcopenia. Gait speed in older adults considerably decreases activities of daily living (ADL). However, the association between ADL and gait speed in older adults with sarcopenia has not yet been fully elucidated. This study aimed to clarify the association between walking speed and ADL in older adults with sarcopenia. Materials and Methods: A total of 72 older adults with sarcopenia who required support or care under Japan\u2019s long-term care insurance system were included. Correlation and multivariate analyses were performed to examine the association between walking speed and ADL performance. A receiver operating characteristic analysis was used to evaluate the discrimination power of gait speed for ADL independence. Results: Gait speed was significantly and positively correlated with the Barthel Index scores for the men and women. ADL were independently and significantly associated with walking speed in the multivariate analysis. The threshold for gait speed that distinguished ADL independence in older adults with sarcopenia was 0.76 m\/s (area under the curve = 0.75, sensitivity 72.7%, specificity 74.0%). Conclusions: Decreased gait speed in older adults with sarcopenia was associated with decreased ADL. Gait speed had high discriminatory power in identifying ADL independence. This indicates that an assessment intervention for gait speed in older adults with sarcopenia may have high clinical utility.<\/jats:p>","DOI":"10.3390\/medicina62020263","type":"journal-article","created":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T15:48:30Z","timestamp":1769442510000},"page":"263","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Declines in Activities in Daily Living of Older Adults with Sarcopenia Were Associated with Gait Speed"],"prefix":"10.3390","volume":"62","author":[{"given":"Ryo","family":"Sato","sequence":"first","affiliation":[{"name":"Integrated Facility for Medical and Long-Term Care, Care Facility for the Elderly \u201cMaronie-en\u201d, 533-4 Iguchi, Nasushiobara 329-2763, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5679-2391","authenticated-orcid":false,"given":"Yohei","family":"Sawaya","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, School of Health Sciences, International University of Health and Welfare, Otawara 324-8501, Japan"},{"name":"Nishinasuno General Home Care Center, Department of Day Rehabilitation, Care Facility for the Elderly \u201cMaronie-en\u201d, Nasushiobara 329-2763, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamaki","family":"Hirose","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, School of Health Sciences, International University of Health and Welfare, Otawara 324-8501, Japan"},{"name":"Nishinasuno General Home Care Center, Department of Day Rehabilitation, Care Facility for the Elderly \u201cMaronie-en\u201d, Nasushiobara 329-2763, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"Shiba","sequence":"additional","affiliation":[{"name":"Integrated Facility for Medical and Long-Term Care, Care Facility for the Elderly \u201cMaronie-en\u201d, 533-4 Iguchi, Nasushiobara 329-2763, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-2204-0329","authenticated-orcid":false,"given":"Lu","family":"Yin","sequence":"additional","affiliation":[{"name":"Integrated Facility for Medical and Long-Term Care, Care Facility for the Elderly \u201cMaronie-en\u201d, 533-4 Iguchi, Nasushiobara 329-2763, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuntaro","family":"Tsuji","sequence":"additional","affiliation":[{"name":"Nishinasuno General Home Care Center, Department of Day Rehabilitation, Care Facility for the Elderly \u201cMaronie-en\u201d, Nasushiobara 329-2763, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Ishizaka","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, School of Health Sciences, International University of Health and Welfare, Otawara 324-8501, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomohiko","family":"Urano","sequence":"additional","affiliation":[{"name":"Integrated Facility for Medical and Long-Term Care, Care Facility for the Elderly \u201cMaronie-en\u201d, 533-4 Iguchi, Nasushiobara 329-2763, Japan"},{"name":"Nishinasuno General Home Care Center, Department of Day Rehabilitation, Care Facility for the Elderly \u201cMaronie-en\u201d, Nasushiobara 329-2763, Japan"},{"name":"Department of Geriatric Medicine, School of Medicine, International University of Health and Welfare, Chiba, Narita 286-8686, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,1,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2164","DOI":"10.1038\/s43587-025-01004-y","article-title":"A focus shift from sarcopenia to muscle health in the Asian Working Group for Sarcopenia 2025 consensus update","volume":"11","author":"Chen","year":"2025","journal-title":"Nat. Aging"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"100016","DOI":"10.1016\/j.jnha.2023.100016","article-title":"The association between sarcopenia and functional disability in older adults","volume":"28","author":"Zhou","year":"2024","journal-title":"J. Nutr. Health Aging"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"307","DOI":"10.4235\/agmr.24.0017","article-title":"Sarcopenia as a robust predictor of readmission within 6 months among individuals experiencing acute stroke","volume":"28","author":"Abe","year":"2024","journal-title":"Ann. Geriatr. Med. Res."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Xiong, L., Liao, T., Guo, T., Zeng, Z., Wang, S., Yang, G., Wang, X., Wang, X., Zhu, J., and Zhao, P. (2023). The relationship between sarcopenia and mortality in Chinese community-dwelling adults: A 7-year cohort study with propensity score matching and Mendelian randomization. Front. Endocrinol., 14.","DOI":"10.3389\/fendo.2023.1215512"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1002\/jcsm.13225","article-title":"Exercise for sarcopenia in older people: A systematic review and network meta-analysis","volume":"14","author":"Shen","year":"2023","journal-title":"J. Cachexia Sarcopenia Muscle"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"155637","DOI":"10.1016\/j.metabol.2023.155637","article-title":"Diet for the prevention and management of sarcopenia","volume":"146","author":"Calvani","year":"2023","journal-title":"Metabolism"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1002\/jcsm.12651","article-title":"Sarcopenia: Prevalence, associated factors, and the risk of mortality and disability in Japanese older adults","volume":"12","author":"Kitamura","year":"2021","journal-title":"J. Cachexia Sarcopenia Muscle"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1111\/ggi.14486","article-title":"Assessing nutritional status in older adults requiring long-term care: Interchangeability of bioelectrical impedance analysis and manual methods for upper arm anthropometric measurements","volume":"22","author":"Sato","year":"2022","journal-title":"Geriatr. Gerontol. Int."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1589\/jpts.35.242","article-title":"Indicators predicting the development and improvement of sarcopenia in older adults requiring long-term care","volume":"35","author":"Sato","year":"2023","journal-title":"J. Phys. Ther. Sci."},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Shiba, T., Sato, R., Sawaya, Y., Hirose, T., Ishizaka, M., Kubo, A., and Urano, T. (2023). Sarcopenia with depression presents a more severe disability than only sarcopenia among Japanese older adults in need of long-term care. Medicina, 59.","DOI":"10.3390\/medicina59061095"},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Silay, K., Selvi, O., and Oztorun, H. (2025). Sarcopenic obesity is linked to worse clinical outcomes than sarcopenia or obesity alone in hospitalized older adults. BMC Geriatr., 25.","DOI":"10.1186\/s12877-025-06105-2"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"235","DOI":"10.4235\/agmr.24.0132","article-title":"The Korean long-term care system: 2024 update","volume":"28","author":"Ga","year":"2024","journal-title":"Ann. Geriatr. Med. Res."},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Takahashi, S., Yonekura, Y., Takanashi, N., and Tanno, K. (2022). Risk factors of long-term care insurance certification in Japan: A scoping review. Int. J. Environ. Res. Public Health, 19.","DOI":"10.3390\/ijerph19042162"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"149","DOI":"10.31662\/jmaj.2020-0027","article-title":"Epidemiologic research on healthy life expectancy and proposal for its extension: A revised English version of Japanese in the Journal of the Japan Medical Association","volume":"3","author":"Tsuji","year":"2020","journal-title":"JMA J."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1111\/ggi.14704","article-title":"Association between decreased neck circumference and impaired activities of daily living among older adults in long-term care","volume":"23","author":"Sato","year":"2023","journal-title":"Geriatr. Gerontol. Int."},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Dai, S., Wang, S., Jiang, S., Wang, D., and Dai, C. (2023). Bidirectional association between handgrip strength and ADLs disability: A prospective cohort study. Front. Public Health, 11.","DOI":"10.3389\/fpubh.2023.1200821"},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Iida, H., Seki, T., Sakai, Y., Watanabe, T., Wakao, N., Matsui, H., and Imagama, S. (2021). Low muscle mass affect hip fracture treatment outcomes in older individuals: A single-institution case-control study. BMC Musculoskelet. Disord., 22.","DOI":"10.1186\/s12891-021-04143-6"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1002\/jcsm.12444","article-title":"Gait speed as a mediator of the effect of sarcopenia on dependency in activities of daily living","volume":"10","author":"Izquierdo","year":"2019","journal-title":"J. Cachexia Sarcopenia Muscle"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"666","DOI":"10.12965\/jer.1735056.528","article-title":"Effectiveness of a multimodal exercise rehabilitation program on walking capacity and functionality after a stroke","volume":"13","author":"Pellicer","year":"2017","journal-title":"J. Exerc. Rehabil."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"20240002","DOI":"10.2490\/prm.20240002","article-title":"Improvement in gait speed affects short-term improvement in activities of daily living in patients with moderate and severe knee osteoarthritis","volume":"9","author":"Ohmine","year":"2024","journal-title":"Prog. Rehabil. Med."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"174","DOI":"10.4235\/agmr.20.0037","article-title":"Long-term care system in Japan","volume":"24","author":"Yamada","year":"2020","journal-title":"Ann. Geriatr. Med. Res."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"100006","DOI":"10.1016\/j.jnha.2023.100006","article-title":"Screening for sarcopenia using calf muscle circumference in older adults requiring long-term care","volume":"28","author":"Sato","year":"2024","journal-title":"J. Nutr. Health Aging"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.jamda.2019.12.012","article-title":"Asian Working Group for sarcopenia: 2019 consensus update on sarcopenia diagnosis and treatment","volume":"21","author":"Chen","year":"2020","journal-title":"J. Am. Med. Dir. Assoc."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/j.jamda.2018.09.033","article-title":"Measurement properties of the Barthel Index in geriatric rehabilitation","volume":"20","author":"Bouwstra","year":"2019","journal-title":"J. Am. Med. Dir. Assoc."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"65","DOI":"10.4037\/ajcc2022732","article-title":"Psychometric properties of the Barthel Index used at intensive care unit discharge","volume":"31","author":"Figueiredo","year":"2022","journal-title":"Am. J. Crit. Care"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1007\/s12603-009-0214-7","article-title":"Validation of the mini nutritional assessment short-form (MNA-SF): A practical tool for identification of nutritional status","volume":"13","author":"Kaiser","year":"2009","journal-title":"J. Nutr. Health Aging"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1111\/j.1651-2227.2006.00178.x","article-title":"Understanding diagnostic tests 3: Receiver operating characteristic curves","volume":"96","author":"Akobeng","year":"2007","journal-title":"Acta Paediatr."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"291","DOI":"10.4235\/agmr.24.0010","article-title":"Association between gait speed and balance disorders in older adults from 12 high Andean Peruvian communities, 2013\u20132019","volume":"28","author":"Parodi","year":"2024","journal-title":"Ann. Geriatr. Med. Res."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1111\/ggi.14583","article-title":"Leg skeletal muscle mass asymmetry is independently associated with gait speed in older adults requiring long-term care","volume":"23","author":"Sato","year":"2023","journal-title":"Geriatr. Gerontol. Int."},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Beck Jepsen, D., Robinson, K., Ogliari, G., Montero-Odasso, M., Kamkar, N., Ryg, J., Freiberger, E., and Masud, T. (2022). Predicting falls in older adults: An umbrella review of instruments assessing gait, balance, and functional mobility. BMC Geriatr., 22.","DOI":"10.1186\/s12877-022-03271-5"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"529.e1","DOI":"10.1016\/j.jamda.2013.04.006","article-title":"Usual gait speed independently predicts mortality in very old people: A population-based study","volume":"14","author":"Toots","year":"2013","journal-title":"J. Am. Med. Dir. Assoc."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"100327","DOI":"10.1016\/j.aohep.2021.100327","article-title":"Frailty and reduced gait speed are independently related to mortality of cirrhotic patients in long-term follow-up","volume":"25","author":"Soto","year":"2021","journal-title":"Ann. Hepatol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"e17529","DOI":"10.7717\/peerj.17529","article-title":"Decrease in the usual walking speed and body fat percentage associated with a deterioration in long-term care insurance certification levels","volume":"12","author":"Sawaya","year":"2024","journal-title":"PeerJ"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/jcsm.12502","article-title":"Muscle mass, strength, and physical performance predicting activities of daily living: A meta-analysis","volume":"11","author":"Wang","year":"2020","journal-title":"J. Cachexia Sarcopenia Muscle"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"161","DOI":"10.2147\/CIA.S494781","article-title":"Effect of exercise and nutrition intervention for older adults with impaired physical function with preserved muscle mass (functional sarcopenia): A randomized controlled trial","volume":"20","author":"Ji","year":"2025","journal-title":"Clin. Interv. Aging"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"afaf104","DOI":"10.1093\/ageing\/afaf104","article-title":"Low gait speed is better than frailty and sarcopenia at identifying the risk of disability in older adults","volume":"54","author":"Luiz","year":"2025","journal-title":"Age Ageing"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1007\/s12603-009-0246-z","article-title":"Gait speed at usual pace as a predictor of adverse outcomes in community-dwelling older people an International Academy on Nutrition and Aging (IANA) Task Force","volume":"13","author":"Rolland","year":"2009","journal-title":"J. Nutr. Health Aging"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1093\/gerona\/60.10.1304","article-title":"Gait velocity as a single predictor of adverse events in healthy seniors aged 75 years and older","volume":"60","author":"Schapira","year":"2005","journal-title":"J. Gerontol. A Biol. Sci. Med. Sci."},{"key":"ref_39","first-page":"1610","article-title":"Physical activity and sarcopenia in community-dwelling older adults with long-term care insurance","volume":"11","author":"Kitamura","year":"2021","journal-title":"Eur. J. Investig. Health Psychol. Educ."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"3806","DOI":"10.1038\/s41598-018-21917-6","article-title":"Multimorbidity patterns in relation to polypharmacy and dosage frequency: A nationwide, cross-sectional study in a Japanese population","volume":"8","author":"Aoki","year":"2018","journal-title":"Sci. Rep."},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Trabassi, D., Castiglia, S.F., Bini, F., Marinozzi, F., Ajoudani, A., Lorenzini, M., Chini, G., Varrecchia, T., Ranavolo, A., and De Icco, R. (2024). Optimizing rare disease gait classification through data balancing and generative AI: Insights from hereditary cerebellar ataxia. Sensors, 24.","DOI":"10.3390\/s24113613"},{"key":"ref_42","doi-asserted-by":"crossref","unstructured":"Scataglini, S., Abts, E., Van Bocxlaer, C., Van den Bussche, M., Meletani, S., and Truijen, S. (2024). Accuracy, validity, and reliability of markerless camera-based 3D motion capture systems versus marker-based 3D motion capture systems in gait analysis: A systematic review and meta-analysis. Sensors, 24.","DOI":"10.3390\/s24113686"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1097\/MLR.0000000000001359","article-title":"Claims-based frailty indices: A systematic review","volume":"58","author":"Shashikumar","year":"2020","journal-title":"Med. Care"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1159\/000521288","article-title":"Charlson Comorbidity Index: A critical review of clinimetric properties","volume":"91","author":"Charlson","year":"2022","journal-title":"Psychother. Psychosom."},{"key":"ref_45","first-page":"640","article-title":"Assessment of activities and participation of people by rehabilitation-focused clinical registries: A systematic scoping review","volume":"59","author":"Oliveros","year":"2023","journal-title":"Eur. J. Phys. Rehabil. Med."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1055\/a-1990-0201","article-title":"Sarcopenia-definition, radiological diagnosis, clinical significance","volume":"195","author":"Vogele","year":"2023","journal-title":"Rofo"},{"key":"ref_47","doi-asserted-by":"crossref","unstructured":"Papadopoulou, S.K., Voulgaridou, G., Kondyli, F.S., Drakaki, M., Sianidou, K., Andrianopoulou, R., Rodopaios, N., and Pritsa, A. (2022). Nutritional and nutrition-related biomarkers as prognostic factors of sarcopenia, and their role in disease progression. Diseases, 10.","DOI":"10.3390\/diseases10030042"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"291","DOI":"10.3233\/IES-201148","article-title":"Isokinetic testing of muscle strength of older individuals with sarcopenia or frailty: A systematic review","volume":"28","author":"Steffl","year":"2020","journal-title":"Isokinet. Exerc. Sci."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1002\/jcsm.13161","article-title":"Predictive validity of current sarcopenia definitions (EWGSOP2, SDOC, and AWGS2) for clinical outcomes: A scoping review","volume":"1","author":"Stuck","year":"2023","journal-title":"J. Cachexia Sarcopenia Muscle"}],"container-title":["Medicina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1648-9144\/62\/2\/263\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T05:10:33Z","timestamp":1769836233000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1648-9144\/62\/2\/263"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,26]]},"references-count":49,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2026,2]]}},"alternative-id":["medicina62020263"],"URL":"https:\/\/doi.org\/10.3390\/medicina62020263","relation":{},"ISSN":["1648-9144"],"issn-type":[{"value":"1648-9144","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,26]]}}}