{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T22:47:43Z","timestamp":1793832463385,"version":"4.6.1"},"reference-count":72,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T00:00:00Z","timestamp":1769990400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Phacoemulsification is performed within a highly dynamic intraocular environment, in which fluid exchange, pressure regulation, and tissue biomechanics interact continuously. Although modern cataract surgery is considered safe and efficient, disruption of this delicate intraoperative microenvironment remains a major source of complications. Among fluidics-related events, post-occlusion break surge represents one of the most critical destabilizing factors of the anterior chamber. A surge occurs when the sudden release of an occluded aspiration port generates an abrupt pressure\u2013volume imbalance that cannot be immediately compensated by infusion, leading to a transient collapse of the intraocular environment. This narrative review integrates current experimental and clinical evidence on the pathophysiology, quantification, and technological control of surge, framing it as a model of environmentally driven intraoperative stress. The evolution of phacoemulsification fluidics, from gravity-based systems to active, adaptive, and predictive platforms, is analyzed in relation to their ability to preserve a stable and physiologic intraocular environment. Comparative data from contemporary devices are reviewed, highlighting differences in surge volume, recovery time, and pressure restitution. Special emphasis is placed on the impact of surge on the microenvironments of both the anterior and posterior segments, including endothelial stress, capsular instability, vitreoretinal traction, and macular perfusion. Emerging strategies such as handpiece-integrated pressure sensors, predictive fluidics algorithms, intraoperative imaging, and artificial intelligence are reshaping environmental control during surgery. Despite substantial technological progress, the complete elimination of surge remains an unmet need. Continued innovation, standardized biomechanical models, and robust clinical validation will be essential to further protect the intraoperative intraocular environment and improve long-term visual outcomes.<\/jats:p>","DOI":"10.3390\/medicina62020298","type":"journal-article","created":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T12:49:44Z","timestamp":1770036584000},"page":"298","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Occlusion Break Surge and Anterior Chamber Stability in the Intraocular Environment of Modern Phacoemulsification: A Narrative Review"],"prefix":"10.3390","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-6407-2342","authenticated-orcid":false,"given":"Hugo","family":"Scarfone","sequence":"first","affiliation":[{"name":"Cl\u00ednica de Ojos Tandil, Tandil B7000, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilia Carolina","family":"Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Cl\u00ednica de Ojos Tandil, Tandil B7000, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7751-5350","authenticated-orcid":false,"given":"Javier","family":"Diez","sequence":"additional","affiliation":[{"name":"Instituto de F\u00edsica Arroyo Seco, Universidad Nacional del Centro de la Provincia de Buenos Aires, CIFICEN-CONICET-CICPBA, Tandil B7000, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Scarfone","sequence":"additional","affiliation":[{"name":"Cl\u00ednica de Ojos Tandil, Tandil B7000, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franco","family":"Scarfone","sequence":"additional","affiliation":[{"name":"Clinica Charles, Buenos Aires C1116, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,2,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/s10384-014-0318-4","article-title":"Preserve the (intraocular) environment: The importance of maintaining normal oxygen gradients in the eye","volume":"58","author":"Beebe","year":"2014","journal-title":"Jpn. 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