{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T23:53:55Z","timestamp":1774655635261,"version":"3.50.1"},"reference-count":37,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: The integration of digital planning and point-of-care (POC) manufacturing has expanded rapidly in oral and maxillofacial surgery (OMFS); however, evidence focusing on regulated, platform-based workflows and their clinical impact remains limited. This study aimed to evaluate the clinical and organizational impact of implementing a unified digital ecosystem centered on the B-Onic platform in routine OMFS practice. Materials and Methods: A retrospective observational study was conducted comparing OMFS procedures planned and executed using the B-Onic platform with a historical control cohort managed with conventional workflows. Surgical cases were categorized into four pathology-based subgroups: facial trauma, oncologic resection and reconstruction, orthognathic surgery, and craniofacial or skull base surgery. Outcomes included preoperative planning time, validation time for guides and implants, surgical duration, intraoperative plan modifications, postoperative complications, 30-day rehospitalization rates, length of hospital stay, and estimated intraoperative blood loss. Results: A total of 110 cases managed using the B-Onic platform were compared with 72 historical control cases. Implementation of the platform was associated with significant reductions in preoperative planning time, validation time, and surgical duration. Clinically relevant improvements were observed in postoperative outcomes, including lower complication rates, reduced 30-day rehospitalization, shorter hospital stays, fewer intraoperative plan modifications, and decreased estimated blood loss. The magnitude of benefit was greatest in high-complexity procedures\u2014particularly oncologic resection and reconstruction and craniofacial or skull base surgery\u2014while more modest effects were observed in orthognathic surgery, reflecting optimized baseline outcomes. Conclusions: The adoption of a regulated, platform-based POC digital ecosystem in oral and maxillofacial surgery is associated with meaningful improvements in workflow efficiency, surgical reproducibility, and postoperative outcomes, especially in complex procedures. These findings support the integration of unified digital platforms as a core component of contemporary OMFS practice and provide OMFS-specific evidence of their clinical and organizational value.<\/jats:p>","DOI":"10.3390\/medicina62020319","type":"journal-article","created":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T09:02:01Z","timestamp":1770195721000},"page":"319","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["B-Onic Platform for Point-of-Care 3D Printing in Oral and Maxillofacial Surgery: Clinical Implementation and Surgical Impact"],"prefix":"10.3390","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6253-9800","authenticated-orcid":false,"given":"Jos\u00e9 Luis","family":"Cebri\u00e1n-Carretero","sequence":"first","affiliation":[{"name":"Maxillofacial Surgery Department, La Paz University Hospital, 3D FabLab, IdiPAZ, 28046 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Pamp\u00edn-Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Maxillofacial Surgery Department, La Paz University Hospital, 3D FabLab, IdiPAZ, 28046 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Tadeo Borjas","family":"G\u00f3mez","sequence":"additional","affiliation":[{"name":"FabLab, La Paz University Hospital, IdiPAZ, 28046 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-5619-7721","authenticated-orcid":false,"given":"Celia","family":"del Peso Ley","sequence":"additional","affiliation":[{"name":"FabLab, La Paz University Hospital, IdiPAZ, 28046 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rub\u00e9n","family":"Rubio Bolivar","sequence":"additional","affiliation":[{"name":"FabLab, La Paz University Hospital, IdiPAZ, 28046 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-9607-9178","authenticated-orcid":false,"given":"Celia","family":"Mat\u00edn Cubillo","sequence":"additional","affiliation":[{"name":"FabLab, La Paz University Hospital, IdiPAZ, 28046 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7757-8885","authenticated-orcid":false,"given":"B\u00e1rbara","family":"Mart\u00ednez de Miguel","sequence":"additional","affiliation":[{"name":"FabLab, La Paz University Hospital, IdiPAZ, 28046 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Montserrat","family":"Bret Zurita","sequence":"additional","affiliation":[{"name":"FabLab, La Paz University Hospital, IdiPAZ, 28046 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federico","family":"Guti\u00e9rrez Larraya","sequence":"additional","affiliation":[{"name":"Chidren\u2019s Cardiology Department, La Paz University Hospital, 3D FabLab, IdiPAZ, 28046 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"Cobas Gamallo","sequence":"additional","affiliation":[{"name":"La Paz University Hospital, 28046 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9869-9240","authenticated-orcid":false,"given":"Carlos","family":"Navarro-Cu\u00e9llar","sequence":"additional","affiliation":[{"name":"Maxillofacial Surgery Department, Gregorio Mara\u00f1\u00f3n University Hospital, Universidad Complutense de Madrid, 28007 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-2660-370X","authenticated-orcid":false,"given":"Jorge","family":"Maga\u00f1a","sequence":"additional","affiliation":[{"name":"Rayo Seco Systems, ISP-XR Systems, C\/Jos\u00e9 de Echegaray, 28232 Las Rozas de Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,2,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1016\/j.surg.2015.12.017","article-title":"Advantages and disadvantages of 3-dimensional printing in surgery: A systematic review","volume":"159","author":"Martelli","year":"2016","journal-title":"Surgery"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1186\/s12938-016-0236-4","article-title":"3D-printing techniques in a medical setting: A systematic literature review","volume":"15","author":"Tack","year":"2016","journal-title":"Biomed. 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