{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T16:23:31Z","timestamp":1791563011571,"version":"4.3.4"},"reference-count":94,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:00:00Z","timestamp":1773100800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicina"],"abstract":"<jats:p>Background and Objectives: Due to the evolution of cataract surgery into a refractive procedure in which optimizing visual quality extends beyond achieving good visual acuity, high-order aberrations have been increasingly recognized as important contributors to postoperative visual performance. This scoping review aims to map and synthesize the available evidence on higher-order aberrations in the context of cataract surgery, with a focus on the surgical techniques, intraocular lens (IOL) design, measurement factors, and their association with the visual outcomes. Materials and Methods: A scoping review was conducted in accordance with the PRISMA-ScR guidelines. A search of electronic databases was performed using a predefined Boolean strategy, complemented by a manual screening of reference lists and independent searches. Studies evaluating higher-order aberrations (HOAs) before and\/or after cataract surgery were included. Data were charted descriptively, and findings were synthesized narratively. Results: A total of 94 studies were included. The evidence shows that differences in HOA profiles are based on the surgical techniques, IOL designs (monofocal, multifocal, toric, and extended depth-of-focus), and measurement devices. Increased HOAs were frequently associated with reduced contrast sensitivity, especially under mesopic conditions. Tear-film instability and pupil size were additional factors contributing to dynamic changes in wavefront aberrations. Considerable methodological heterogeneity was observed across studies. Conclusions: The current body of evidence suggests a strong connection between corneal characteristics, IOL design, surgical techniques, patient-specific factors, and postoperative visual quality. HOAs play an important but not an exclusive role. Future research should focus on standardized measurement approaches, population-specific optical considerations, and personalized strategies to optimize visual quality after cataract surgery.<\/jats:p>","DOI":"10.3390\/medicina62030512","type":"journal-article","created":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T10:53:31Z","timestamp":1773140011000},"page":"512","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["High-Order Aberrations in Cataract Surgery: Current Status and Future Perspectives: A Scoping Review"],"prefix":"10.3390","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-4138-6854","authenticated-orcid":false,"given":"Andreea Alexandra Mihaela","family":"Musat","sequence":"first","affiliation":[{"name":"Doctoral School, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Calin Petru","family":"Tataru","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, Central Emergency University Military Hospital, 010825 Bucharest, Romania"},{"name":"Ophthalmology Department, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6731-3341","authenticated-orcid":false,"given":"Gabriela Cornelia","family":"Musat","sequence":"additional","affiliation":[{"name":"ENT Department, Saint Mary Clinical Hospital, 011172 Bucharest, Romania"},{"name":"ENT Department, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5376-7975","authenticated-orcid":false,"given":"Vanda Roxana","family":"Nimigean","sequence":"additional","affiliation":[{"name":"Department of Oral Rehabilitation, Faculty of Dentistry, Carol Davila University of Medicine and Pharmacy, 4-6 Eforie Street, 050037 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0172-5962","authenticated-orcid":false,"given":"Mihai Alexandru","family":"Preda","sequence":"additional","affiliation":[{"name":"ENT Department, Saint Mary Clinical Hospital, 011172 Bucharest, Romania"},{"name":"ENT Department, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ovidiu","family":"Musat","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, Central Emergency University Military Hospital, 010825 Bucharest, Romania"},{"name":"Ophthalmology Department, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,3,10]]},"reference":[{"key":"ref_1","first-page":"60","article-title":"Impact of Cataract Surgery on Higher Order Aberrations and Comparative Analysis using Scheimpflug imaging and ray-tracing technology","volume":"69","author":"Saxena","year":"2025","journal-title":"Rom. 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