{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:37:21Z","timestamp":1792805841229,"version":"4.5.0"},"reference-count":30,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2018,6,12]],"date-time":"2018-06-12T00:00:00Z","timestamp":1528761600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"International Foundation for Sciences","award":["AF\/20286"],"award-info":[{"award-number":["AF\/20286"]}],"id":[{"id":"https:\/\/ror.org\/03pwwck46","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicines"],"abstract":"<jats:p>Background: According to recent studies, reactive oxygen is the leader of human metabolic disease development. The use of natural antioxidants is the best way to stop or prevent this problem. Therefore, the aim of this study was to evaluate the antioxidant and anti-inflammatory activities and to determine the polyphenolic contents of the Bidens engleri and Boerhavia erecta fractions. Methods: Plant fractions were obtained using Soxhlet procedures with hexane, dichloromethane, acetonitrile, ethyl acetate, methanol, and butanol solvent, successively. The different fractions were compared according to their antioxidant, anti-inflammatory activities, total phenolic, and total flavonoid contents. The phenolic contribution to the biological activity was evaluated. Result: The Bidens engleri and Boerhavia erecta fractions showed the highest antioxidant abilities, notably the polar fractions, which inhibited significantly the radical 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2-O-azinobis(3-ethylbenzoline-6-sulphonate) (ABTS). The butanol fraction from Bidens engleri and methanol fraction from Boerhavia erecta have presented the best iron (III) reduction power with 211.68 and 198.55 mgAAE\/g, respectively. Butanol and acetonitrile were the best solvents for extracting phenolic compounds from Bidens engleri and Boerhavia erecta, respectively. In contrast, dichloromethane was the best solvent for extracting a flavonoid from two plants with anti-COX-2 and anti-LOX-15 active compounds. The phenolic compound contributed significantly to antioxidant activity (r &gt; 0.80). Conclusion: The Bidens engleri and Boerhavia erecta fractions possessed a potential antioxidant for fighting oxidative stress and helping to prevent diabetes, hypertension, and cardiovascular diseases. The uses of this plant could be promoted in Burkina Faso.<\/jats:p>","DOI":"10.3390\/medicines5020053","type":"journal-article","created":{"date-parts":[[2018,6,12]],"date-time":"2018-06-12T10:58:32Z","timestamp":1528801112000},"page":"53","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Antioxidant and Anti-Inflammatory Activities of Fractions from Bidens engleri O.E. Schulz (Asteraceae) and Boerhavia erecta L. (Nyctaginaceae)"],"prefix":"10.3390","volume":"5","author":[{"given":"Moussa","family":"COMPAORE","sequence":"first","affiliation":[{"name":"Laboratory of Applied Biochemistry and Chemistry, University Ouaga I JKZ, Ouagadougou 03 BP 7021, Burkina Faso"},{"name":"Culture Platform of Cell and Tissue (PCCT) U.F.R\/S.V.T., University Ouaga I JKZ, Ouagadougou 09 BP 1001, Burkina Faso"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sahabi","family":"BAKASSO","sequence":"additional","affiliation":[{"name":"Laboratory of Natural Products and Organic Synthesis, Department of Chemistry, Faculty of Science and Technology Abdou Moumouni University of Niamey, Niamey BP 10662, Niger"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roland","family":"MEDA","sequence":"additional","affiliation":[{"name":"Laboratory for Research and Education in Animal Health and Biotechnology, University Nazi Boni of Bobo-Dioulasso, Bobo-Dioulasso 01 BP 1091, Burkina Faso"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Odile","family":"NACOULMA","sequence":"additional","affiliation":[{"name":"Laboratory of Applied Biochemistry and Chemistry, University Ouaga I JKZ, Ouagadougou 03 BP 7021, Burkina Faso"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2018,6,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.cca.2014.06.004","article-title":"Antioxidants and human diseases","volume":"436","author":"Rajendran","year":"2014","journal-title":"Clin. 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