{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T02:40:08Z","timestamp":1775184008602,"version":"3.50.1"},"reference-count":16,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2022,12,2]],"date-time":"2022-12-02T00:00:00Z","timestamp":1669939200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicines"],"abstract":"<jats:p>Diabetic Charcot arthropathy of the ankle, due to the presence of multiplanar deformities, and associated medical comorbidities, poses a challenge for treating physicians. The situation becomes more complicated when accompanied by ulceration and osteomyelitis, leaving limited salvage options. We present a case of advanced Charcot ankle arthropathy with osteomyelitis and ulcerated hindfoot. It was managed by talectomy and antibiotic-impregnated cement beads, followed by hindfoot arthrodesis using a retrograde intramedullary nail six weeks later. This two-stage reconstruction approach resulted in an ulcer-free, stable, plantigrade foot at one-year postoperative follow-up.<\/jats:p>","DOI":"10.3390\/medicines9120061","type":"journal-article","created":{"date-parts":[[2022,12,5]],"date-time":"2022-12-05T05:31:32Z","timestamp":1670218292000},"page":"61","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Salvage of Hindfoot Charcot with Osteomyelitis and Ulceration: A Case Report"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7404-0214","authenticated-orcid":false,"given":"Khalid","family":"Hasan","sequence":"first","affiliation":[{"name":"Department of Orthopedics, Virginia Commonwealth University (VCU), Richmond, VA 23298, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sreenivasulu","family":"Metikala","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Virginia Commonwealth University (VCU), Richmond, VA 23298, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madana Mohana R.","family":"Vallem","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Virginia Commonwealth University (VCU), Richmond, VA 23298, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,12,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2123","DOI":"10.2337\/dc11-0844","article-title":"The Charcot foot in diabetes","volume":"34","author":"Rogers","year":"2011","journal-title":"Diabetes Care"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1007\/s00132-009-1504-9","article-title":"Reconstructive surgery for Charcot foot. Long-term 5-year outcome","volume":"38","author":"Illgner","year":"2009","journal-title":"Der Orthop."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"008","DOI":"10.4172\/2329-910X.S3-008","article-title":"Infections of Charcot Feet: Diagnostics and Treatment","volume":"S3","author":"Illgner","year":"2014","journal-title":"Clin. Res. Foot Ankle"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"42","DOI":"10.15557\/JoU.2018.0007","article-title":"Diabetic foot syndrome: Charcot arthropathy or osteomyelitis? Part I: Clinical picture and radiography","volume":"18","author":"Konarzewska","year":"2018","journal-title":"J. Ultrason."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.jcot.2021.02.016","article-title":"The use of circular frame external fixation in the treatment of ankle\/hindfoot Charcot Neuroarthropathy","volume":"16","author":"Martin","year":"2021","journal-title":"J. Clin. Orthop. Trauma"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"2842","DOI":"10.1016\/j.injury.2017.10.036","article-title":"The psychological impact of external fixation using the Ilizarov or Orthofix LRS method to treat tibial osteomyelitis with a bone defect","volume":"48","author":"Abulaiti","year":"2017","journal-title":"Injury"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.jcot.2020.03.025","article-title":"Charcot foot reconstruction outcomes: A systematic review","volume":"11","author":"Ha","year":"2020","journal-title":"J. Clin. Orthop. Trauma"},{"key":"ref_8","unstructured":"Kelikian, H., and Kelikian, A.S. (1985). Disorders of the Ankle, W.B. Saunders Company."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0002-9610(43)90501-X","article-title":"Comminuted fractures and fracture dislocations of the body of the astragalus: Operative treatment","volume":"59","author":"Blair","year":"1943","journal-title":"Am. J. Surg."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1700","DOI":"10.2106\/00004623-199811000-00019","article-title":"Operative treatment of neuropathic arthropathy of the foot and ankle","volume":"80","author":"Johnson","year":"1998","journal-title":"J. Bone Jt. Surg."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.3113\/FAI.2012.1069","article-title":"Treatment of osteomyelitis in charcot foot with single-stage resection of infection, correction of deformity, and maintenance with ring fixation","volume":"33","author":"Pinzur","year":"2012","journal-title":"Foot Ankle Int."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1177\/1071100712460209","article-title":"Antibiotic-coated nail for fusion of infected Charcot ankles","volume":"34","author":"Pawar","year":"2013","journal-title":"Foot Ankle Int."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1053\/j.jfas.2015.12.008","article-title":"Surgical Management of Charcot Deformity for the Foot and Ankle-Radiologic Outcome After Inter-nal\/External Fixation","volume":"55","author":"Ettinger","year":"2016","journal-title":"J. Foot Ankle Surg."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"820826","DOI":"10.3389\/fsurg.2022.820826","article-title":"Charcot Neuroarthropathy: Current Surgical Management and Update. A Systematic Review","volume":"9","author":"Bajuri","year":"2022","journal-title":"Front. Surg."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"34","DOI":"10.5005\/jp-journals-10080-1450","article-title":"Pelvic Support Hip Reconstruction with Internal Devices: An Alternative to Ilizarov Hip Reconstruction","volume":"15","author":"Metikala","year":"2020","journal-title":"Strateg. Trauma Limb Reconstr."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1053\/j.jfas.2018.08.059","article-title":"Risk Factors Associated With Major Lower Extremity Amputation After Osseous Diabetic Charcot Re-construction","volume":"58","author":"Elmarsafi","year":"2019","journal-title":"J. Foot Ankle Surg."}],"container-title":["Medicines"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2305-6320\/9\/12\/61\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:32:41Z","timestamp":1760146361000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2305-6320\/9\/12\/61"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,2]]},"references-count":16,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2022,12]]}},"alternative-id":["medicines9120061"],"URL":"https:\/\/doi.org\/10.3390\/medicines9120061","relation":{},"ISSN":["2305-6320"],"issn-type":[{"value":"2305-6320","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,2]]}}}