{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T19:31:44Z","timestamp":1783971104706,"version":"3.55.0"},"reference-count":46,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medical Sciences"],"abstract":"<jats:p>The USPSTF and ACS recommend screening for breast, cervical, colorectal, and lung cancers. Rates of cancer screening, diagnosis, and treatment decreased significantly in the US and other developed nations during the height of the COVID-19 pandemic and lockdown (April 2020) and have since recovered, although not to baseline levels in many cases. For breast cancer, the USPSTF recommends biennial screening with mammography for women aged 50\u201374, while the ACS recommends annual screening for women aged 45\u201354, who may transition to biennial after 55. Minority and rural populations have lower rates of screening and lower utilization of DBT, which offers superior sensitivity and specificity. Among 20 US health networks in April 2020, mammography rates were down 89.2% and new breast cancer diagnoses down by 50.5%. For cervical cancer, the USPSTF recommends cervical cytology every three years for women 21\u201365, or cytology+hrHPV co-testing every five years for women aged 30\u201365. Cervical cancer screening rates declined by 87% in April 2020 and recovered to a 40% decline by June 2020, with American Indians and Asians most severely affected. For colorectal cancer (CRC), the USPSTF and ACS recommend screening for ages 45\u201375, recently lowered from a starting age of 50. Most commonly-used modalities include annual FIT testing, FIT+DNA testing every three years, and colonoscopy every ten years, with shorter repeat if polyps are found. In the US, CRC screenings were down by 79\u201384.5% in April 2020 across several retrospective studies. Patient encounters for CRC were down by 39.9%, and a UK-based model predicted that 5-year-survival would decrease by 6.4%. The USPSTF recommends screening low dose CT scans (LDCTs) for ages 50\u201380 with a &gt;20 pack-year smoking history who have smoked within the past 15 years. In April 2020, screening LDCTs fell by 72\u201378% at one US institution and lung cancer diagnoses were down 39.1%.<\/jats:p>","DOI":"10.3390\/medsci10010016","type":"journal-article","created":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T21:25:14Z","timestamp":1646169914000},"page":"16","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["US Cancer Screening Recommendations: Developments and the Impact of COVID-19"],"prefix":"10.3390","volume":"10","author":[{"given":"Adam","family":"Barsouk","sequence":"first","affiliation":[{"name":"Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA 15232, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kalyan","family":"Saginala","sequence":"additional","affiliation":[{"name":"Plains Regional Medical Group Internal Medicine, Clovis, NM 88101, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John Sukumar","family":"Aluru","sequence":"additional","affiliation":[{"name":"Senior Research Associate, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02212, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4361-8498","authenticated-orcid":false,"given":"Prashanth","family":"Rawla","sequence":"additional","affiliation":[{"name":"Hospitalist, Parrish Medical Center, Titusville, FL 32796, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Barsouk","sequence":"additional","affiliation":[{"name":"Hematologist-Oncologist, Allegheny Health Network, Pittsburgh, PA 15212, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,3,1]]},"reference":[{"key":"ref_1","first-page":"29","article-title":"USPSTF Breast Cancer Screening Guidelines","volume":"112","author":"Davisson","year":"2016","journal-title":"W Va. Med. J."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.1001\/jama.2021.6238","article-title":"Screening for Colorectal Cancer: US Preventive Services Task Force Recommendation Statement","volume":"325","author":"Davidson","year":"2021","journal-title":"JAMA J. Am. Med. Assoc."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1001\/jamasurg.2021.0242","article-title":"New USPSTF Guidelines for Lung Cancer Screening","volume":"156","author":"Colson","year":"2021","journal-title":"JAMA Surg."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.prnil.2020.06.002","article-title":"Impact of the evolving United States Preventative Services Task Force policy statements on incidence and distribution of prostate cancer over 15 years in a statewide cancer registry","volume":"9","author":"Jeong","year":"2021","journal-title":"Prostate Int."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1200\/CCI.20.00068","article-title":"Effects of the COVID-19 Pandemic on Cancer-Related Patient Encounters","volume":"4","author":"London","year":"2020","journal-title":"JCO Clin. Cancer Inf."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/S1470-2045(20)30388-0","article-title":"The impact of the COVID-19 pandemic on cancer deaths due to delays in diagnosis in England, UK: A national, population-based, modelling study","volume":"21","author":"Maringe","year":"2020","journal-title":"Lancet Oncol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"e200618","DOI":"10.1001\/jamanetworkopen.2020.0618","article-title":"Association of Neighborhood Measures of Social Determinants of Health with Breast, Cervical, and Colorectal Cancer Screening Rates in the US Midwest","volume":"3","author":"Kurani","year":"2020","journal-title":"JAMA Netw. Open"},{"key":"ref_8","unstructured":"Howlander, N., Noone, A.M., Krapcho, M., Miller, D., Brest, A., Yu, M., Ruhl, J., Tatalovich, Z., Mariotto, A., and Lewis, D.R. (2019). SEER Cancer Statistics Review 1975\u20132016."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.1001\/jama.2015.12783","article-title":"Breast cancer screening for women at average risk: 2015 Guideline update from the American cancer society","volume":"314","author":"Oeffinger","year":"2015","journal-title":"JAMA J. Am. Med. Assoc."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"320","DOI":"10.2214\/AJR.10.4656","article-title":"Detection and classification of calcifications on digital breast tomosynthesis and 2D digital mammography: A comparison","volume":"192","author":"Spangler","year":"2011","journal-title":"Am. J. Roentgenol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/s43055-021-00421-4","article-title":"Comparing the diagnostic efficacy of digital breast tomosynthesis with full-field digital mammography using BI-RADS scoring","volume":"52","author":"Naeim","year":"2021","journal-title":"Egypt. J. Radiol. Nucl. Med."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1177\/0284185119863989","article-title":"Breast compression parameters among women screened with standard digital mammography and digital breast tomosynthesis in a randomized controlled trial","volume":"61","author":"Waade","year":"2020","journal-title":"Acta Radiol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1148\/radiol.2019182947","article-title":"Breast MRI: State of the art","volume":"292","author":"Mann","year":"2019","journal-title":"Radiology"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.clinimag.2018.10.017","article-title":"Abbreviated protocol breast MRI: The past, present, and future","volume":"53","author":"Greenwood","year":"2019","journal-title":"Clin. Imaging"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1016\/j.jacr.2020.12.033","article-title":"Outcomes by Race in Breast Cancer Screening with Digital Breast Tomosynthesis Versus Digital Mammography","volume":"18","author":"Alsheik","year":"2021","journal-title":"J. Am. Coll. Radiol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1002\/cncr.29221","article-title":"Impact of patient and navigator race and language concordance on care after cancer screening abnormalities","volume":"121","author":"Charlot","year":"2015","journal-title":"Cancer"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.amepre.2016.03.017","article-title":"Follow-Up of Abnormal Breast and Colorectal Cancer Screening by Race\/Ethnicity","volume":"51","author":"McCarthy","year":"2016","journal-title":"Am. J. Prev. Med."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1200\/CCI.20.00134","article-title":"Impact of COVID-19 on Cancer Care: How the Pandemic Is Delaying Cancer Diagnosis and Treatment for American Seniors","volume":"4","author":"Patt","year":"2020","journal-title":"JCO Clin. Cancer Inform."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"4466","DOI":"10.1002\/cncr.33113","article-title":"Breast imaging, breast surgery, and cancer genetics in the age of COVID-19","volume":"126","author":"Yin","year":"2020","journal-title":"Cancer"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1038\/s41416-020-01182-z","article-title":"The COVID-19 pandemic and impact on breast cancer diagnoses: What happened in England in the first half of 2020","volume":"124","author":"Gathani","year":"2021","journal-title":"Br. J. Cancer"},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Tsibulak, I., Reiser, E., Bogner, G., Petru, E., Hell-Teutsch, J., Reinthaller, A., Weirather, C., Weiss, T., Bozsa, S., and Puschacher, B. (2020). Decrease in gynecological cancer diagnoses during the COVID-19 pandemic: An Austrian perspective. Int. J. Gynecol. Cancer, 30.","DOI":"10.1136\/ijgc-2020-001975"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1136\/jclinpath-2020-206833","article-title":"Cancer diagnostic rates during the 2020 \u201clockdown\u201d, due to COVID-19 pandemic, compared with the 2018\u20132019: An audit study from cellular pathology","volume":"74","author":"Carr","year":"2021","journal-title":"J. Clin. Pathol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1093\/jnci\/djab045","article-title":"Changes in Mammography Utilization by Women\u2019s Characteristics during the First 5 Months of the COVID-19 Pandemic","volume":"113","author":"Sprague","year":"2021","journal-title":"JNCI J. Natl. Cancer Inst."},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Gomez, S., Tan, S., Keegan, T.H.M., and Clarke, C.A. (2007). Disparities in mammographic screening for Asian women in California: A cross-sectional analysis to identify meaningful groups for targeted intervention. BMC Cancer, 7.","DOI":"10.1186\/1471-2407-7-201"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1001\/jama.2018.10897","article-title":"Screening for cervical cancer us preventive services task force recommendation statement","volume":"320","author":"Curry","year":"2018","journal-title":"JAMA J. Am. Med. Assoc."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"321","DOI":"10.3322\/caac.21628","article-title":"Cervical cancer screening for individuals at average risk: 2020 guideline update from the American Cancer Society","volume":"70","author":"Fontham","year":"2020","journal-title":"CA. Cancer J. Clin."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1056\/NEJMoa1917338","article-title":"HPV Vaccination and the Risk of Invasive Cervical Cancer","volume":"383","author":"Lei","year":"2020","journal-title":"N. Engl. J. Med."},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Kind, A.B., Pavelyev, A., Kothari, S., El Mouaddin, N., Schmidt, A., Morais, E., Guggisberg, P., and Lienert, F. (2020). Assessing the epidemiological impact on cervical cancer of switching from 4-valent to 9-valent HPV vaccine within a gender-neutral vaccination programme in Switzerland. BMC Public Health, 20.","DOI":"10.1186\/s12889-020-08840-0"},{"key":"ref_29","first-page":"1183","article-title":"National, Regional, State, and Selected Local Area Vaccination Coverage Among Adolescents Aged 13\u201317 Years\u2014United States, 2020","volume":"70","author":"Pingali","year":"2021","journal-title":"MMWR Recomm. Rep."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"106559","DOI":"10.1016\/j.ypmed.2021.106559","article-title":"COVID-19 impact on screening test volume through the National Breast and Cervical Cancer early detection program, January\u2013June 2020, in the United States","volume":"151","author":"DeGroff","year":"2021","journal-title":"Prev. Med."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"109","DOI":"10.15585\/mmwr.mm7004a1","article-title":"Impact of COVID-19 on Cervical Cancer Screening Rates Among Women Aged 21\u201365 Years in a Large Integrated Health Care System\u2014Southern California, January 1\u2013September 30, 2019, and January 1\u2013September 30, 2020","volume":"70","author":"Miller","year":"2021","journal-title":"MMWR. Morb. Mortal. Wkly. Rep."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1159\/000509546","article-title":"The Impact of the COVID-19 Pandemic and the Associated Belgian Governmental Measures on Cancer Screening, Surgical Pathology and Cytopathology","volume":"88","author":"Guiot","year":"2021","journal-title":"Pathobiology"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"k4823","DOI":"10.1136\/bmj.k4823","article-title":"Detecting cervical precancer and reaching underscreened women by using HPV testing on self samples: Updated meta-analyses","volume":"363","author":"Arbyn","year":"2018","journal-title":"BMJ"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"250","DOI":"10.3322\/caac.21457","article-title":"Colorectal cancer screening for average-risk adults: 2018 guideline update from the American Cancer Society","volume":"68","author":"Wolf","year":"2018","journal-title":"CA Cancer J. Clin."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1007\/s10900-020-00867-z","article-title":"Systematic Review of Interventions to Increase Stool Blood Colorectal Cancer Screening in African Americans","volume":"46","author":"Roy","year":"2021","journal-title":"J. Community Health"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1053\/j.gastro.2020.10.030","article-title":"Cancer Screening during the Coronavirus Disease-2019 Pandemic: A Perspective from the National Cancer Institute\u2019s PROSPR Consortium","volume":"160","author":"Corley","year":"2021","journal-title":"Gastroenterology"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1177\/0969141320974711","article-title":"The impact of episodic screening interruption: COVID-19 and population-based cancer screening in Canada","volume":"28","author":"Yong","year":"2020","journal-title":"J. Med. Screen."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"e5","DOI":"10.1016\/j.clcc.2020.07.006","article-title":"Impact of COVID-19 Pandemic on Colorectal Cancer Screening Program","volume":"20","author":"Lucidi","year":"2021","journal-title":"Clin. Colorectal Cancer"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1111\/codi.15408","article-title":"Adoption of faecal immunochemical testing for 2-week-wait colorectal patients during the COVID-19 pandemic: An observational cohort study reporting a new service at a regional centre","volume":"23","author":"Maclean","year":"2021","journal-title":"Color. Dis."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1136\/gutjnl-2020-321650","article-title":"Prioritisation by FIT to mitigate the impact of delays in the 2-week wait colorectal cancer referral pathway during the COVID-19 pandemic: A UK modelling study","volume":"70","author":"Loveday","year":"2021","journal-title":"Gut"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1053\/j.gastro.2021.04.026","article-title":"Noninvasive Colorectal Cancer Screening Tests Help Close Screening Gaps during Coronavirus Disease 2019 Pandemic","volume":"161","author":"Myint","year":"2021","journal-title":"Gastroenterology"},{"key":"ref_42","first-page":"116","article-title":"Pandemic Spotlights In-home Colon Cancer Screening Tests","volume":"325","author":"Jaklevic","year":"2021","journal-title":"JAMA J. Am. Med. Assoc."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"e200107","DOI":"10.1148\/rycan.2020200107","article-title":"Lung Cancer Screening in African Americans: The Time to Act Is Now","volume":"2","author":"Prosper","year":"2020","journal-title":"Radiol. Imaging Cancer"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1001\/jamaoncol.2019.1402","article-title":"Evaluation of USPSTF Lung Cancer Screening Guidelines among African American Adult Smokers","volume":"5","author":"Aldrich","year":"2019","journal-title":"JAMA Oncol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1016\/j.chest.2020.10.045","article-title":"Operational Challenges of a Low-Dose CT Lung Cancer Screening Program during the Coronavirus Disease 2019 Pandemic","volume":"159","author":"Lang","year":"2021","journal-title":"Chest"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/j.jamcollsurg.2020.12.002","article-title":"Impact of the COVID-19 Pandemic on Lung Cancer Screening Program and Subsequent Lung Cancer","volume":"232","author":"Delman","year":"2021","journal-title":"J. Am. Coll. 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