{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T06:40:49Z","timestamp":1771828849407,"version":"3.50.1"},"reference-count":18,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T00:00:00Z","timestamp":1731024000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["23K16360"],"award-info":[{"award-number":["23K16360"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["24rea522104s0103"],"award-info":[{"award-number":["24rea522104s0103"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Japan Agency for Medical Research and Development","award":["23K16360"],"award-info":[{"award-number":["23K16360"]}]},{"name":"Japan Agency for Medical Research and Development","award":["24rea522104s0103"],"award-info":[{"award-number":["24rea522104s0103"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medical Sciences"],"abstract":"<jats:p>Background: The reddening of the face and neck following alcohol consumption is known as Asian flush. Although genetic factors related to Asian flush have been reported to be inversely associated with duration of sleep, no study has reported an association between Asian flush and sleep satisfaction. Methods: A cross-sectional study of 3823 Japanese people, aged 20 to 64 years was conducted. The target population comprised general public resident monitors of Osaka Prefecture who were registered with an internet research company. Results: A significant inverse association was observed between Asian flush and satisfaction of sleep. The potential confounder-adjusted odds ratio (OR) and 95% confidence interval (CI) of satisfied sleep was 0.81 (0.69\u20130.96). The alcohol consumption status-specific analysis revealed essentially the same associations between consumers and non-consumers of alcohol. The adjusted ORs (95% CIs) were 0.81 (0.65\u20130.997) for non-consumers and 0.80 (0.61\u20131.05) for consumers of alcohol. Conclusion: The genetic characteristics of physical reactions to alcohol exposure may influence sleep quality. One\u2019s alcohol consumption status may not influence the effects of having a lower tolerance to alcohol on sleep quality.<\/jats:p>","DOI":"10.3390\/medsci12040062","type":"journal-article","created":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T03:53:14Z","timestamp":1731383594000},"page":"62","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Association Between Asian Flush and Satisfaction of Sleep via Alcohol Consumption Status in a Sample of Japanese Participants"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3381-9288","authenticated-orcid":false,"given":"Yuji","family":"Shimizu","sequence":"first","affiliation":[{"name":"Epidemiology Section, Division of Public Health, Osaka Institute of Public Health, Osaka 537-0025, Japan"},{"name":"Department of General Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8501, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomokatsu","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Epidemiology Section, Division of Public Health, Osaka Institute of Public Health, Osaka 537-0025, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiko","family":"Ito","sequence":"additional","affiliation":[{"name":"Epidemiology Section, Division of Public Health, Osaka Institute of Public Health, Osaka 537-0025, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kumiko","family":"Terada","sequence":"additional","affiliation":[{"name":"Epidemiology Section, Division of Public Health, Osaka Institute of Public Health, Osaka 537-0025, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nagisa","family":"Sasaki","sequence":"additional","affiliation":[{"name":"Epidemiology Section, Division of Public Health, Osaka Institute of Public Health, Osaka 537-0025, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eiko","family":"Honda","sequence":"additional","affiliation":[{"name":"Epidemiology Section, Division of Public Health, Osaka Institute of Public Health, Osaka 537-0025, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazushi","family":"Motomura","sequence":"additional","affiliation":[{"name":"Epidemiology Section, Division of Public Health, Osaka Institute of Public Health, Osaka 537-0025, Japan"},{"name":"Department of Public Health, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,11,8]]},"reference":[{"key":"ref_1","first-page":"22","article-title":"ALDH2, ADH1B, and ADH1C genotypes in Asians: A literature review","volume":"30","author":"Eng","year":"2007","journal-title":"Alcohol. 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