{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T01:23:31Z","timestamp":1792027411140,"version":"4.4.0"},"reference-count":32,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2025,4,5]],"date-time":"2025-04-05T00:00:00Z","timestamp":1743811200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006769","name":"Russian Science Foundation","doi-asserted-by":"publisher","award":["23-78-01117"],"award-info":[{"award-number":["23-78-01117"]}],"id":[{"id":"10.13039\/501100006769","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medical Sciences"],"abstract":"<jats:p>Introduction: Pediatric cancer survivors are at high risk for visual\u2013motor and cognitive deficits that persist throughout life. These domains are related to academic performance. The current study examined (i) whether both visuomotor and cognitive functions and (ii) whether visuomotor functions alone mediate the relationship between age and cognitive functions. Methods: In total, there were 210 participants (7\u201317 years): 70 posterior fossa tumors (Mage = 12.1\u2009 \u00b1 \u20093.2 years, 44% female) and 70 acute lymphoblastic leukemia (Mage = 12.3\u2009 \u00b1 \u20093.4 years, 45% female) survivors and 70 (Mage = 12.2 \u00b1\u20093.3 years, 41% female) healthy controls. Visual motor integration, motor coordination and visual perception were assessed using the Beery VMI test. Working memory, attention and planning were assessed using CANTAB. Results: Impaired motor function is significantly more pronounced than cognitive impairment in both groups of cancer survivors (effect size from 25 to 30% for visual\u2013motor and from 5 to 7% for cognitive functions). A multiple regression model revealed that age and visual motor functions are significant predictors of attention (in the ALL group \u03b2 = \u22120.490, t = \u22124.88, p = 0.000) and working memory (in the PFT group \u03b2 = 0.264, t = 2.72, p = 0.008; in the ALL group \u03b2 = 0.215, t = 2.24, p = 0.028). Conclusions: In children who have experienced acute lymphoblastic leukemia and tumors of the posterior cranial fossa, visual\u2013motor dysfunction is more pronounced than cognitive impairment. In addition, there is an association between visual\u2013motor function disorders and working memory. These findings can be used to develop more specific rehabilitation protocols.<\/jats:p>","DOI":"10.3390\/medsci13020041","type":"journal-article","created":{"date-parts":[[2025,4,7]],"date-time":"2025-04-07T11:24:39Z","timestamp":1744025079000},"page":"41","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Visual\u2013Motor Functions and Associated Cognitive Outcomes in Pediatric Cancer Survivors"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7666-1089","authenticated-orcid":false,"given":"Alena","family":"Deviaterikova","sequence":"first","affiliation":[{"name":"Research Institute for Brain Development and Peak Performance, RUDN University, Mikluho-Maklaya, Str., 11, Moscow 117198, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,4,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1136\/archdischild-2019-317594","article-title":"Educational attainment in childhood cancer survivors: A meta-analysis","volume":"105","author":"Saatci","year":"2020","journal-title":"Arch. 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