{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T17:33:43Z","timestamp":1786469623573,"version":"build-2736575974"},"reference-count":218,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T00:00:00Z","timestamp":1786406400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Research Foundation for Youth Scholars of Beijing Technology and Business University","award":["RFYS2025"],"award-info":[{"award-number":["RFYS2025"]}]},{"award":["RFYS2025"],"award-info":[{"award-number":["RFYS2025"]}],"id":[{"id":"https:\/\/ror.org\/013e0zm98","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Membranes"],"abstract":"<jats:p>Hollow fiber loose nanofiltration (HF-LNF) has attracted increasing attention as a pressure-driven membrane platform that combines loose nanofiltration (LNF) selectivity with the high packing density and self-supporting geometry of hollow fibers. This review critically evaluates recent advances in HF-LNF membranes, including controllable fabrication strategies, surface functionalization techniques, and practical engineering applications, with a discussion of life cycle assessment (LCA) for evaluating the environmental and economic sustainability of HF membrane systems. Phase inversion, interfacial polymerization (IP), coating, and grafting are compared in terms of structural controllability, process complexity, selective-layer stability, modification uniformity, reproducibility, and scale-up feasibility. Phase inversion is relatively compatible with continuous hollow-fiber spinning, but independent regulation of the support and selective layer remains difficult. IP provides greater control over selective-layer chemistry and effective pore size, whereas coating and grafting offer flexible surface functionalization but may be limited by additional transport resistance, layer durability, and non-uniform modification of curved surfaces. Direct HF-LNF application remains concentrated on dye\/salt separation. Based on the evidence from HF-NF or flat LNF systems, the potential of HF-LNF in water softening, heavy metal removal and emerging pollutant control is analyzed. Critical challenges restricting industrial translation are discussed, including poor long-term antifouling capacity and difficulties in large-scale, low-cost manufacturing. On this basis, LCA is further introduced as a decision-support framework for identifying potential environmental hotspots in membrane manufacturing and operation, while the limited availability and comparability of HF-LNF-specific life-cycle data are explicitly recognized. Ultimately, it is proposed to focus on novel functional materials, eco-friendly preparation processes, and scaled membrane engineering, aiming to offer theoretical support for the rational design and real-world industrial deployment of next-generation HF-LNF membranes.<\/jats:p>","DOI":"10.3390\/membranes16080266","type":"journal-article","created":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T16:30:32Z","timestamp":1786465832000},"page":"266","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Review of Tunable Hollow Fiber Loose Nanofiltration Membranes: Fabrication, Surface Functionalization and Sustainable Water Treatment with Life Cycle Assessment"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-2120-4718","authenticated-orcid":false,"given":"Jiajie","family":"Liu","sequence":"first","affiliation":[{"name":"School of Light Industry Science and Engineering, Beijing Technology and Business University, Beijing 100048, China"},{"name":"Key Laboratory of Cleaner Production and Integrated Resource Utilization of China National Light Industry, Beijing Technology and Business University, Beijing 100048, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuoqing","family":"Shi","sequence":"additional","affiliation":[{"name":"School of Light Industry Science and Engineering, Beijing Technology and Business University, Beijing 100048, China"},{"name":"Key Laboratory of Cleaner Production and Integrated Resource Utilization of China National Light Industry, Beijing Technology and Business University, Beijing 100048, China"},{"name":"Institute of Nuclear and New Energy Technology, Tsinghua University, Beijing 100084, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Light Industry Science and Engineering, Beijing Technology and Business University, Beijing 100048, China"},{"name":"Key Laboratory of Cleaner Production and Integrated Resource Utilization of China National Light Industry, Beijing Technology and Business University, Beijing 100048, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suping","family":"Yu","sequence":"additional","affiliation":[{"name":"School of Light Industry Science and Engineering, Beijing Technology and Business University, Beijing 100048, China"},{"name":"Key Laboratory of Cleaner Production and Integrated Resource Utilization of China National Light Industry, Beijing Technology and Business University, Beijing 100048, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2922-1045","authenticated-orcid":false,"given":"Liming","family":"Dong","sequence":"additional","affiliation":[{"name":"School of Light Industry Science and Engineering, Beijing Technology and Business University, Beijing 100048, China"},{"name":"Key Laboratory of Cleaner Production and Integrated Resource Utilization of China National Light Industry, Beijing Technology and Business University, Beijing 100048, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,8,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"118461","DOI":"10.1016\/j.desal.2024.118461","article-title":"A comprehensive study of recent advances, challenges and factors of nanofiltration membrane in various industrial applications","volume":"599","author":"Usha","year":"2025","journal-title":"Desalination"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1039\/D0CS01599G","article-title":"Tailored design of nanofiltration membranes for water treatment based on synthesis\u2013property\u2013performance relationships","volume":"51","author":"Wang","year":"2022","journal-title":"Chem. 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