{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T17:46:55Z","timestamp":1791049615302,"version":"4.1.0"},"reference-count":162,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2022,8,31]],"date-time":"2022-08-31T00:00:00Z","timestamp":1661904000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Metabolites"],"abstract":"<jats:p>The ability of microorganisms to detoxify xenobiotic compounds allows them to thrive in a toxic environment using carbon, phosphorus, sulfur, and nitrogen from the available sources. Biotransformation is the most effective and useful metabolic process to degrade xenobiotic compounds. Microorganisms have an exceptional ability due to particular genes, enzymes, and degradative mechanisms. Microorganisms such as bacteria and fungi have unique properties that enable them to partially or completely metabolize the xenobiotic substances in various ecosystems.There are many cutting-edge approaches available to understand the molecular mechanism of degradative processes and pathways to decontaminate or change the core structure of xenobiotics in nature. These methods examine microorganisms, their metabolic machinery, novel proteins, and catabolic genes. This article addresses recent advances and current trends to characterize the catabolic genes, enzymes and the techniques involved in combating the threat of xenobiotic compounds using an eco-friendly approach.<\/jats:p>","DOI":"10.3390\/metabo12090818","type":"journal-article","created":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T01:50:51Z","timestamp":1661997051000},"page":"818","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":202,"title":["Degradation of Xenobiotic Pollutants: An Environmentally Sustainable Approach"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9889-3067","authenticated-orcid":false,"given":"Rashi","family":"Miglani","sequence":"first","affiliation":[{"name":"Department of Zoology, D.S.B Campus, Kumaun University, Nainital 263002, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5428-0664","authenticated-orcid":false,"given":"Nagma","family":"Parveen","sequence":"additional","affiliation":[{"name":"Department of Zoology, D.S.B Campus, Kumaun University, Nainital 263002, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ankit","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, Sir J. C Bose Technical Campus, Bhimtal, Nainital 263136, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohd. Arif","family":"Ansari","sequence":"additional","affiliation":[{"name":"Department of Forestry and Environmental Science, D.S.B Campus, Kumaun University, Nainital 263002, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soumya","family":"Khanna","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Banaras Hindu University, Varanasi 221005, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3752-3174","authenticated-orcid":false,"given":"Gaurav","family":"Rawat","sequence":"additional","affiliation":[{"name":"Department of Zoology, D.S.B Campus, Kumaun University, Nainital 263002, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amrita Kumari","family":"Panda","sequence":"additional","affiliation":[{"name":"Department of Biotechnology, Sant Gahira Guru University, Ambikapur 497001, Chhattisgarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5886-6638","authenticated-orcid":false,"given":"Satpal Singh","family":"Bisht","sequence":"additional","affiliation":[{"name":"Department of Zoology, D.S.B Campus, Kumaun University, Nainital 263002, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jyoti","family":"Upadhyay","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, School of Health Sciences and Technology, University of Petroleum and Energy Studies, Energy Acre Campus Bidholi, Dehradun 248007, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8580-3002","authenticated-orcid":false,"given":"Mohd Nazam","family":"Ansari","sequence":"additional","affiliation":[{"name":"Department of Pharmacology and Toxicology, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,8,31]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.3389\/fmicb.2018.01132","article-title":"Understanding and designing the strategies for the microbe-mediated remediation of environmental contaminants using omics approaches","volume":"9","author":"Malla","year":"2018","journal-title":"Front. 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