{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:26:59Z","timestamp":1760059619875,"version":"build-2065373602"},"reference-count":25,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T00:00:00Z","timestamp":1750723200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Metabolites"],"abstract":"<jats:p>Multiple acyl-CoA dehydrogenase deficiency (MADD), also known as glutaric acidemia\/glutaric aciduria type II (GA II), is an inborn error of fatty acid, amino acid, and choline metabolism. The chronic management of MADD involves both dietary fat and protein restriction to reduce the substrates of the dehydrogenases affected, the avoidance of prolonged fasting as in any fat metabolism disorder, and monitoring for potential complications. Due to its rarity, there is little published experience on the management of MADD in pregnancy. Herein, we report the successful management of a pregnancy in a patient with late-onset or type III MADD, with considerations for preconception, antepartum, intrapartum, and postpartum care.<\/jats:p>","DOI":"10.3390\/metabo15070432","type":"journal-article","created":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T04:37:21Z","timestamp":1750739841000},"page":"432","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Management of Multiple Acyl-CoA Dehydrogenase Deficiency (MADD) in Pregnancy"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4134-5665","authenticated-orcid":false,"given":"Matthew A.","family":"Shear","sequence":"first","affiliation":[{"name":"Division of Maternal-Fetal Medicine and Reproductive Genetics, Department of Obstetrics, Gynecology, & Reproductive Sciences, University of California, 490 Illinois Street, Box 0132, San Francisco, CA 94143, USA"},{"name":"Division of Medical Genetics, Department of Pediatrics, University of California, San Francisco, CA 94143, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allie","family":"LaTray","sequence":"additional","affiliation":[{"name":"Division of Medical Genetics, Department of Pediatrics, University of California, San Francisco, CA 94143, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irene J.","family":"Chang","sequence":"additional","affiliation":[{"name":"Division of Medical Genetics, Department of Pediatrics, University of California, San Francisco, CA 94143, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9037-5496","authenticated-orcid":false,"given":"Annalisa","family":"Post","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine and Reproductive Genetics, Department of Obstetrics, Gynecology, & Reproductive Sciences, University of California, 490 Illinois Street, Box 0132, San Francisco, CA 94143, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1611-0354","authenticated-orcid":false,"given":"Renata C.","family":"Gallagher","sequence":"additional","affiliation":[{"name":"Division of Medical Genetics, Department of Pediatrics, University of California, San Francisco, CA 94143, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,6,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Ou, M., Zhu, L., Zhang, Y., Zhang, Y., Zhou, J., Zhang, Y., Chen, X., Yang, L., Li, T., and Su, X. 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