{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T02:35:02Z","timestamp":1789785302791,"version":"4.0.1"},"reference-count":181,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2023,9,30]],"date-time":"2023-09-30T00:00:00Z","timestamp":1696032000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Instituto Tecnol\u00f3gico de Estudios Superiores de Monterrey"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Micromachines"],"abstract":"<jats:p>Copper nanoparticles (CuNPs) can be synthesized by green methods using plant extracts. These methods are more environmentally friendly and offer improved properties of the synthesized NPs in terms of biocompatibility and functional capabilities. Traditional medicine has a rich history of utilization of herbs for millennia, offering a viable alternative or complementary option to conventional pharmacological medications. Plants of traditional herbal use or those with medicinal properties are candidates to be used to obtain NPs due to their high and complex content of biocompounds with different redox capacities that provide a dynamic reaction environment for NP synthesis. Other synthesis conditions, such as salt precursor concentration, temperature, time synthesis, and pH, have a significant effect on the characteristics of the NPs. This paper will review the properties of some compounds from medicinal plants, plant extract obtention methods alternatives, characteristics of plant extracts, and how they relate to the NP synthesis process. Additionally, the document includes diverse applications associated with CuNPs, starting from antibacterial properties to potential applications in metabolic disease treatment, vegetable tissue culture, therapy, and cardioprotective effect, among others.<\/jats:p>","DOI":"10.3390\/mi14101882","type":"journal-article","created":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T16:58:09Z","timestamp":1696179489000},"page":"1882","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":113,"title":["Biosynthesis of Copper Nanoparticles with Medicinal Plants Extracts: From Extraction Methods to Applications"],"prefix":"10.3390","volume":"14","author":[{"given":"Aurora","family":"Antonio-P\u00e9rez","sequence":"first","affiliation":[{"name":"Departamento de Bioingenier\u00eda, Escuela de Ingenier\u00eda y Ciencias, Tecnologico de Monterrey, Campus Estado de M\u00e9xico, Av. Lago de Guadalupe KM 3.5, Margarita Maza de Ju\u00e1rez, Atizap\u00e1n de Zaragoza, Ciudad L\u00f3pez Mateos 52926, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6884-8372","authenticated-orcid":false,"given":"Luis Fernando","family":"Dur\u00e1n-Armenta","sequence":"additional","affiliation":[{"name":"VIB-VUB Center for Structural Biology, Vlaams Instituut voor Biotechnologie, Pleinlaan 2, 1050 Brussels, Belgium"},{"name":"Structural Biology Brussels, Vrije Universiteit Brussel, 1050 Brussels, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Guadalupe","family":"P\u00e9rez-Loredo","sequence":"additional","affiliation":[{"name":"Departamento de Bioingenier\u00eda, Escuela de Ingenier\u00eda y Ciencias, Tecnologico de Monterrey, Campus Estado de M\u00e9xico, Av. Lago de Guadalupe KM 3.5, Margarita Maza de Ju\u00e1rez, Atizap\u00e1n de Zaragoza, Ciudad L\u00f3pez Mateos 52926, Mexico"},{"name":"Divisi\u00f3n Acad\u00e9mica de Tecnolog\u00eda Ambiental, Universidad Tecnol\u00f3gica Fidel Vel\u00e1zquez, Av. Emiliano Zapata S\/N, El Tr\u00e1fico, Nicol\u00e1s Romero C.P.54400, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4645-5102","authenticated-orcid":false,"given":"Ana Laura","family":"Torres-Huerta","sequence":"additional","affiliation":[{"name":"Departamento de Bioingenier\u00eda, Escuela de Ingenier\u00eda y Ciencias, Tecnologico de Monterrey, Campus Estado de M\u00e9xico, Av. 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