{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:33:36Z","timestamp":1760150016512,"version":"build-2065373602"},"reference-count":16,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2023,9,30]],"date-time":"2023-09-30T00:00:00Z","timestamp":1696032000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Micromachines"],"abstract":"<jats:p>Since contact lenses directly contact the cornea, the surface roughness of the lens may cause various side effects. In addition, gold nanoparticles can realize a variety of colors and characteristics depending on their shape and size. In this study, the surface roughness of tinted lenses containing gold nanoparticles of various sizes was analyzed using atomic force microscopy (AFM) at aspect ratio(surface to volume ratio) ranging from 1:1 to 1:10. The characteristics of the lenses were then confirmed. As a result, tinted lenses with different colors depending on the size of the gold nanoparticles were manufactured. The surface roughness of the lens decreased with increasing size of the gold nanoparticles. However, at aspect ratio of 1:10, increase in surface roughness was observed. In addition, it was confirmed that the wettability and antibacterial properties of the lens had the same effect according to the average surface roughness value. Therefore, it was confirmed that the addition of gold nanoparticles reduced the surface roughness of the lens, which had a great effect on properties such as wettability and antimicrobial properties of the lens. The produced copolymer controls the surface roughness of the lens, and thus it is judged that it can be used as a material for various ophthalmology applications.<\/jats:p>","DOI":"10.3390\/mi14101883","type":"journal-article","created":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T16:58:09Z","timestamp":1696179489000},"page":"1883","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Correlation Analysis of Surface and Physical Properties of Ophthalmic Lenses Containing Nanoparticles"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4981-2566","authenticated-orcid":false,"given":"Su-Mi","family":"Shin","sequence":"first","affiliation":[{"name":"Department of Optometry & Vision Science, Daegu Catholic University, Gyeongsan 38430, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hye-In","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Optometry & Vision Science, Daegu Catholic University, Gyeongsan 38430, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A-Young","family":"Sung","sequence":"additional","affiliation":[{"name":"Department of Optometry & Vision Science, Daegu Catholic University, Gyeongsan 38430, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,9,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"173","DOI":"10.3807\/JOSK.2007.11.4.173","article-title":"The Change of Blink Rate by Wearing Soft Contact Lens","volume":"11","author":"Lee","year":"2006","journal-title":"J. Korean Ophthalmic Opt. Soc."},{"key":"ref_2","first-page":"43","article-title":"Changes in Objective and Subjective Responses in Soft Contact Lens Wearers Refitted to Daily-Wear Silicone Hydrogel Contact Lenses","volume":"12","author":"Lee","year":"2007","journal-title":"J. Korean Ophthalmic Opt. Soc."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1080\/08164622.2022.2033604","article-title":"Global contact lens prescribing 2000\u20132020","volume":"105","author":"Morgan","year":"2022","journal-title":"Clin. Exp. Optom."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1177\/0885328215581507","article-title":"Timolol maleate release from hyaluronic acid-containing model silicone hydrogel contact lens materials","volume":"30","author":"Korogiannaki","year":"2015","journal-title":"J. Biomater. Appl."},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Tran, N.P.D., and Yang, M.C. (2019). Synthesis and characterization of silicone contact lenses based on TRIS-DMA-NVP-HEMA hydrogels. Polymers, 11.","DOI":"10.3390\/polym11060944"},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Lee, M.J., Park, S.Y., and Sung, A.Y. (2022). Ophthalmic Hydrogel Contact Lens Material Containing Magnesium Oxide Nanoparticles and 3-(Trifluoromethyl) styrene for Biomedical Application. Micromachines, 13.","DOI":"10.3390\/mi13111897"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.clae.2020.03.012","article-title":"The COVID-19 pandemic: Important considerations for contact lens practitioners","volume":"43","author":"Jones","year":"2020","journal-title":"Contact Lens Anterior Eye"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"3217","DOI":"10.1016\/S0142-9612(01)00159-4","article-title":"Bacterial adhesion to surface hydrophilic and hydrophobic contact lenses","volume":"22","author":"Bruinsma","year":"2001","journal-title":"Biomaterials"},{"key":"ref_9","unstructured":"Giraldez, M.J., and Yebra-Pimentel, E. (2012). Ocular Diseases, IntechOpen."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"4870","DOI":"10.1021\/acsnano.0c09657","article-title":"Gold nanocomposite contact lenses for color blindness management","volume":"15","author":"Salih","year":"2021","journal-title":"ACS Nano"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"102538","DOI":"10.1016\/j.jddst.2021.102538","article-title":"In vitro and in vivo evaluation of ketotifen-gold nanoparticles laden contact lens for controlled drug delivery to manage conjunctivitis","volume":"64","author":"Guo","year":"2021","journal-title":"J. Drug Deliv. Sci. Technol."},{"key":"ref_12","first-page":"180","article-title":"Anti-Acanthamoeba effects of silver and gold nanoparticles and contact lenses disinfection solutions","volume":"13","author":"Niyyati","year":"2018","journal-title":"Iran. J. Parasitol."},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Shin, S.M., Park, H.I., and Sung, A.Y. (2022). Development of Functional Ophthalmic Materials Using Natural Materials and Gold Nanoparticles. Micromachines, 13.","DOI":"10.3390\/mi13091451"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/0021-9797(77)90251-X","article-title":"Effects of surface roughness on wetting (theoretical)","volume":"60","author":"Huh","year":"1977","journal-title":"J. Colloid Interface Sci."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1002\/jbm.b.32901","article-title":"Surface properties and wear performances of siloxane-hydrogel contact lenses","volume":"101","author":"Bettuelli","year":"2013","journal-title":"J. Biomed. Mater. Res. Part B Appl. Biomater."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1002\/jbm.b.30100","article-title":"Physicochemical factors influencing bacterial transfer from contact lenses to surfaces with different roughness and wettability","volume":"71","author":"Vermeltfoort","year":"2004","journal-title":"J. Biomed. Mater. Res. Part B Appl. Biomater. Off. J. Soc. Biomater. Jpn. Soc. Biomater. Aust. Soc. Biomater. Korean Soc. Biomater."}],"container-title":["Micromachines"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-666X\/14\/10\/1883\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T21:02:40Z","timestamp":1760130160000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-666X\/14\/10\/1883"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,30]]},"references-count":16,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2023,10]]}},"alternative-id":["mi14101883"],"URL":"https:\/\/doi.org\/10.3390\/mi14101883","relation":{},"ISSN":["2072-666X"],"issn-type":[{"type":"electronic","value":"2072-666X"}],"subject":[],"published":{"date-parts":[[2023,9,30]]}}}