{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T17:18:44Z","timestamp":1793207924550,"version":"4.5.0"},"reference-count":31,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:00Z","timestamp":1787702400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22302128"],"award-info":[{"award-number":["22302128"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"award":["22302128"],"award-info":[{"award-number":["22302128"]}],"id":[{"id":"https:\/\/ror.org\/01h0zpd94","id-type":"ROR","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Guangdong Basic and Applied Basic Research Foundation","doi-asserted-by":"crossref","award":["2024A1515010990"],"award-info":[{"award-number":["2024A1515010990"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Guangdong Provincial Medical Science and Technology Research Foundation Project","award":["B2025631"],"award-info":[{"award-number":["B2025631"]}]},{"name":"Shenzhen Science and Technology Program","award":["RCBS20231211090713027"],"award-info":[{"award-number":["RCBS20231211090713027"]}]},{"name":"Development and Reform Commission of Shenzhen Municipality Support Plan for Strategic Emerging Industries","award":["XMHT20240115002"],"award-info":[{"award-number":["XMHT20240115002"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Micromachines"],"abstract":"<jats:p>We present both theoretical and experimental studies on the deformation of aqueous droplets in an alternating-current (AC) electric field. Droplets are first generated using a microfluidic T-junction and are then deformed downstream using a set of coplanar microelectrodes. We investigated how the electric field strength, AC frequencies, conductivities of the aqueous fluids and interfacial tension affect the deformation of droplets in a microchannel. The experimental results are well explained by the electrohydrodynamic (EHD) theory for almost all system parameters explored in this study. Only at very high electric field strengths do the experimental results deviate slightly from the EHD theory. The observed experimental trends can be explained by a series of scaling analyses that provide insights into the interaction of the different physical properties with the electric field. We expect that the present work will provide a better understanding of electrically mediated deformation of droplets in a microchannel.<\/jats:p>","DOI":"10.3390\/mi17091008","type":"journal-article","created":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T11:53:42Z","timestamp":1787745222000},"page":"1008","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Theoretical and Experimental Studies on AC Electric Field Induced Droplet Deformation in a Microchannel"],"prefix":"10.3390","volume":"17","author":[{"given":"Zuxuan","family":"Shen","sequence":"first","affiliation":[{"name":"School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen 518060, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingwen","family":"Yang","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen 518060, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zifeng","family":"Tan","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen 518060, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiapeng","family":"Zhao","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen 518060, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caichan","family":"Li","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen 518060, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1580-8200","authenticated-orcid":false,"given":"Yage","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen 518060, China"},{"name":"Guangdong Key Laboratory of Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen 518060, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyu","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen 518060, China"},{"name":"Guangdong Key Laboratory of Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen University, Shenzhen 518060, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,8,26]]},"reference":[{"key":"ref_1","first-page":"159","article-title":"Studies in electrohydrodynamics. I. The circulation produced in a drop by electric field","volume":"291","author":"Taylor","year":"1966","journal-title":"Proc. R. Soc. A"},{"key":"ref_2","first-page":"295","article-title":"Electrohydrodynamic deformation and bursts of liquid drops","volume":"269","author":"Torza","year":"1971","journal-title":"Philos. Trans. R. Soc. London. Ser. A Math. Phys. Sci."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1017\/S0022112092004294","article-title":"The electrohydrodynamic deformation of drops suspended in liquids in steady and oscillatory electric fields","volume":"239","author":"Vizika","year":"1992","journal-title":"J. Fluid Mech."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1017\/S0022112099007223","article-title":"Deformation and breakup of Newtonian and non-Newtonian conducting drops in an electric field","volume":"405","author":"Ha","year":"2000","journal-title":"J. Fluid Mech."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"054101","DOI":"10.1063\/1.4817008","article-title":"Droplet deformation and manipulation in an electrified microfluidic channel","volume":"103","author":"Wehking","year":"2013","journal-title":"Appl. Phys. Lett."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1039\/C4LC00934G","article-title":"Droplet actuation in an electrified microfluidic network","volume":"15","author":"Wehking","year":"2015","journal-title":"Lab Chip"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1039\/C6LC01435F","article-title":"Active droplet sorting in microfluidics: A review","volume":"17","author":"Xi","year":"2017","journal-title":"Lab Chip"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1039\/C5LC01012H","article-title":"Active droplet generation in microfluidics","volume":"16","author":"Chong","year":"2016","journal-title":"Lab Chip"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"121301","DOI":"10.1063\/5.0241194","article-title":"Generation, migration, and coalescence of droplets: A state-of-the-art review from the perspectives of wettability, inertia, and electric field","volume":"36","author":"Boruah","year":"2024","journal-title":"Phys. Fluids"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"349","DOI":"10.3109\/07388559609147426","article-title":"Electroporation of cell membranes: A review","volume":"16","author":"Ho","year":"1996","journal-title":"Crit. Rev. Biotechnol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1039\/c3lc51143j","article-title":"Microfluidic flow-focusing in ac electric fields","volume":"14","author":"Tan","year":"2014","journal-title":"Lab Chip"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"4787","DOI":"10.1038\/srep04787","article-title":"The Microfluidic Jukebox","volume":"4","author":"Tan","year":"2014","journal-title":"Sci. Rep."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1007\/s10404-015-1603-3","article-title":"Breakup length of AC electrified jets in a microfluidic flow-focusing junction","volume":"19","author":"Tan","year":"2015","journal-title":"Microfluid. Nanofluid."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"043504","DOI":"10.1063\/1.4954194","article-title":"AC electrified jets in a flow-focusing device: Jet length scaling","volume":"10","author":"Tan","year":"2016","journal-title":"Biomicrofluidics"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"2982","DOI":"10.1039\/C6LC00448B","article-title":"AC electric field induced droplet deformation in a microfluidic T-junction","volume":"16","author":"Xi","year":"2016","journal-title":"Lab Chip"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"067001","DOI":"10.1088\/0960-1317\/23\/6\/067001","article-title":"Dielectric breakdown of PDMS thin films","volume":"23","author":"Gerratt","year":"2013","journal-title":"J. Micromech. Microeng."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"072105","DOI":"10.1063\/1.4813236","article-title":"Drop motion, deformation, and cyclic motion in a non-uniform electric field in the viscous limit","volume":"25","author":"Mhatre","year":"2013","journal-title":"Phys. Fluids"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1002\/elps.200600549","article-title":"Transport and deformation of droplets in a microdevice using dielectrophoresis","volume":"28","author":"Singh","year":"2007","journal-title":"Electrophoresis"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1021\/acs.langmuir.2c02235","article-title":"Controlled transport of individual microparticles using dielectrophoresis","volume":"39","author":"Zaman","year":"2023","journal-title":"Langmuir"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"034501","DOI":"10.1103\/PhysRevLett.119.034501","article-title":"Streaming from the equator of a drop in an external electric field","volume":"119","author":"Brosseau","year":"2017","journal-title":"Phys. Rev. Lett."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"12879","DOI":"10.1021\/la4011696","article-title":"Periodic deformation of microsize droplets in a microchannel induced by a transverse alternating electric field","volume":"29","author":"Mochizuki","year":"2013","journal-title":"Langmuir"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"9984","DOI":"10.1021\/acs.langmuir.6c00048","article-title":"Transient deformation and charge evolution during alternating current-electrohydrodynamic oscillations of confined droplets","volume":"42","author":"Gupta","year":"2026","journal-title":"Langmuir"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"033620","DOI":"10.1063\/5.0261782","article-title":"Electrohydrodynamic deformation of a confined droplet in an alternating current electric field: An analytical study","volume":"37","author":"Mohanty","year":"2025","journal-title":"Phys. Fluids"},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Ma, Z., Teo, A.J.T., Tan, S.H., Ai, Y., and Nguyen, N.-T. (2016). Self-aligned interdigitated transducers for acoustofluidics. Micromachines, 7.","DOI":"10.20944\/preprints201611.0086.v2"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"012611","DOI":"10.1103\/PhysRevE.94.012611","article-title":"Dependence of the dielectric constant of electrolyte solutions on ionic concentration: A microfield approach","volume":"94","author":"Gavish","year":"2016","journal-title":"Phys. Rev. E"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1007\/s10404-016-1722-5","article-title":"Automated droplet measurement (ADM): An enhanced video processing software for rapid droplet measurements","volume":"20","author":"Chong","year":"2016","journal-title":"Microfluid. Nanofluid."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1002\/andp.19003060312","article-title":"Zur elektronentheorie der metalle","volume":"306","author":"Drude","year":"1900","journal-title":"Ann. Phys."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1063\/1.38956","article-title":"The circulation produced in a drop by an electric field: A high field strength electrokinetic model","volume":"197","author":"Baygents","year":"1990","journal-title":"AIP Conf. Proc."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"2245","DOI":"10.1098\/rspa.1999.0402","article-title":"Electrohydrodynamic behaviour of a drop subjected to a steady uniform electric field at finite electric Reynolds number","volume":"455","author":"Feng","year":"1999","journal-title":"Proc. R. Soc. A"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"013007","DOI":"10.1103\/PhysRevE.92.013007","article-title":"Electrolytic drops in an electric field: A numerical study of drop deformation and breakup","volume":"92","author":"Pillai","year":"2015","journal-title":"Phys. Rev. E"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"3310","DOI":"10.1039\/C6SM00047A","article-title":"Electrokinetics of isolated electrified drops","volume":"12","author":"Pillai","year":"2016","journal-title":"Soft Matter"}],"container-title":["Micromachines"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2072-666X\/17\/9\/1008\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T04:29:13Z","timestamp":1787891353000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2072-666X\/17\/9\/1008"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,26]]},"references-count":31,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2026,9]]}},"alternative-id":["mi17091008"],"URL":"https:\/\/doi.org\/10.3390\/mi17091008","relation":{},"ISSN":["2072-666X"],"issn-type":[{"value":"2072-666X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,26]]}}}