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In this study, a topology-driven design framework was established for fused deposition modeling (FDM)-printed thermoplastic polyurethane (TPU) tubular lattices. Five auxetic topologies were designed by regulating curvature polarity and structural symmetry, while planar porosity and wall thickness were selected as geometric control parameters. Numerical simulations combined with experimental validation were employed to systematically evaluate axial bending stiffness, radial support force, Poisson\u2019s ratio, and stress distribution. The results demonstrate that geometric curvature promotes radial load transfer through an arch-like mechanism and contributes to stress redistribution, whereas structural symmetry strongly influences axial compliance and auxetic deformation. Planar porosity acts as the dominant macroscopic tuning parameter for overall mechanical performance, while wall thickness provides a secondary fine-tuning mechanism with greater sensitivity to local stress variation. Based on these findings, a hierarchical design strategy integrating topology, planar porosity, and wall thickness is proposed, providing a generalizable approach for tailoring the mechanical performance of FDM-printed elastomeric tubular lattices.<\/jats:p>","DOI":"10.3390\/mi17091092","type":"journal-article","created":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T08:03:17Z","timestamp":1789632197000},"page":"1092","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Topology-Driven Mechanical Tuning of FDM-Printed TPU Tubular Lattices with Auxetic Architectures"],"prefix":"10.3390","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5531-585X","authenticated-orcid":false,"given":"Yun","family":"Zhai","sequence":"first","affiliation":[{"name":"School of Mechanical Engineering, Dalian Jiaotong University, Dalian 116028, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"},{"role":"project-administration","vocabulary":"credit"},{"role":"supervision","vocabulary":"credit"},{"role":"resources","vocabulary":"credit"},{"role":"writing-original-draft","vocabulary":"credit"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"},{"role":"funding-acquisition","vocabulary":"credit"}]},{"given":"Shenhui","family":"Sang","sequence":"additional","affiliation":[{"name":"School of Mechanical Engineering, Dalian Jiaotong University, Dalian 116028, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"software","vocabulary":"credit"},{"role":"writing-original-draft","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"validation","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1844-9303","authenticated-orcid":false,"given":"Yu","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Mechanical Engineering, Dalian Jiaotong University, Dalian 116028, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"resources","vocabulary":"credit"},{"role":"supervision","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"}]},{"given":"David","family":"Hui","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering, University of New Orleans, New Orleans, LA 70148, USA"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"conceptualization","vocabulary":"credit"}]},{"given":"Depeng","family":"Shang","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"funding-acquisition","vocabulary":"credit"},{"role":"project-administration","vocabulary":"credit"},{"role":"writing-review-editing","vocabulary":"credit"}]}],"member":"1968","published-online":{"date-parts":[[2026,9,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Sun, J., Qiao, Y., Zhao, M., Magnussen, C.G., and Xi, B. 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