{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T15:53:58Z","timestamp":1791734038267,"version":"4.3.4"},"reference-count":71,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2022,6,25]],"date-time":"2022-06-25T00:00:00Z","timestamp":1656115200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Universidad Aut\u00f3noma De Aguascalientes","award":["PIBB20-12C"],"award-info":[{"award-number":["PIBB20-12C"]}]},{"name":"Universidad Aut\u00f3noma De Aguascalientes","award":["MP-20-056"],"award-info":[{"award-number":["MP-20-056"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microorganisms"],"abstract":"<jats:p>Cerebral palsy (CP) in children constitutes a set of movement and body posture disorders caused by brain injury, which in turn is associated with a series of intestinal, respiratory, and malnutrition conditions. Twenty-four children were selected and included for the present study and subdivided into two groups: (1) children who included modern kefir (containing 12 probiotic species) in their diet; and (2) control group (not including kefir in their diet). The group supplemented with modern kefir received a beverage with multi probiotic species and the control group received commercial yogurt (which included the 2 typical lactic acid bacteria) for 7 weeks. Anthropometric variables, resting energy expenditure, presence, and diagnosis of functional digestive disorders (FDD), frequency of respiratory problems, presence of elevated C-reactive protein, differential count of leukocytes were evaluated. A significant increase in weight and height was found in the kefir group at the final time point. In addition, kefir intake promoted a significant reduction in functional constipation and stool hardness and increased the absolute value of blood lymphocytes. Since the fermented milk beverage modern kefir improves constipation, which is the most important FDD in children with CP and the nutritional and immune status, it could be considered an important strategy to improve health in these children.<\/jats:p>","DOI":"10.3390\/microorganisms10071291","type":"journal-article","created":{"date-parts":[[2022,6,26]],"date-time":"2022-06-26T21:01:41Z","timestamp":1656277301000},"page":"1291","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Effects of a Modern Kefir on Conditions Associated with Moderate Severe Spastic Quadriparesis Cerebral Palsy"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0134-9688","authenticated-orcid":false,"given":"Ad\u00e1n Israel","family":"Rodr\u00edguez-Hern\u00e1ndez","sequence":"first","affiliation":[{"name":"Departamento de Nutrici\u00f3n, Universidad Aut\u00f3noma de Aguascalientes, Av, Universiades 940, Aguascalientes C.P. 20100, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3570-7255","authenticated-orcid":false,"given":"Eva","family":"Salinas","sequence":"additional","affiliation":[{"name":"Laboratorio de Inmunolog\u00eda, Departamento de Microbiolog\u00eda, Universidad Aut\u00f3noma de Aguascalientes, Av, Universidad 940, Aguascalientes C.P. 20100, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deli Nazm\u00edn","family":"Tirado Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Departamento de Ingenier\u00edas, Tecnol\u00f3gico Nacional de M\u00e9xico (TecNM), Instituto Tecnol\u00f3gico El Llano Aguascalientes, Carr. Aguascalientes-S.L.P km 18.5, El Llano, Aguascalientes C.P. 20330, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4062-5326","authenticated-orcid":false,"given":"Carlos","family":"Velasco Benitez","sequence":"additional","affiliation":[{"name":"Departamento de Pediatr\u00eda Cali-Colombia, Universidad del Valle, Cali C.P. 76001, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1141-4271","authenticated-orcid":false,"given":"Mariela","family":"Jim\u00e9nez","sequence":"additional","affiliation":[{"name":"Laboratorio de Inmunolog\u00eda, Departamento de Microbiolog\u00eda, Universidad Aut\u00f3noma de Aguascalientes, Av, Universidad 940, Aguascalientes C.P. 20100, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura E","family":"C\u00f3rdova-D\u00e1valos","sequence":"additional","affiliation":[{"name":"Laboratorio de Inmunolog\u00eda, Departamento de Microbiolog\u00eda, Universidad Aut\u00f3noma de Aguascalientes, Av, Universidad 940, Aguascalientes C.P. 20100, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9711-8042","authenticated-orcid":false,"given":"Daniel","family":"Cervantes-Garc\u00eda","sequence":"additional","affiliation":[{"name":"Laboratorio de Inmunolog\u00eda, Departamento de Microbiolog\u00eda, Universidad Aut\u00f3noma de Aguascalientes, Av, Universidad 940, Aguascalientes C.P. 20100, Mexico"},{"name":"Consejo Nacional de Ciencia y Tecnologia, Av. Insurgentes Sur 1582, Ciudad de M\u00e9xico C.P. 03940, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor Federico","family":"Rodr\u00edguez Nava","sequence":"additional","affiliation":[{"name":"Departamento de Enfermer\u00eda, Universidad Aut\u00f3noma de Aguascalientes, Av, Universidad 940, Aguascalientes C.P. 20100, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7525-3131","authenticated-orcid":false,"given":"Luis G.","family":"Berm\u00fadez-Humar\u00e1n","sequence":"additional","affiliation":[{"name":"Micalis Institute, Universit\u00e9 Paris-Saclay, INRAE, AgroParisTech, 78350 Jouy-en-Josas, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,6,25]]},"reference":[{"key":"ref_1","unstructured":"National Center on Birth Defects and Developmental Disabilities C for DC and P (2020, December 30). 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