{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T20:06:48Z","timestamp":1789157208324,"version":"build-2803163510"},"reference-count":49,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2022,8,12]],"date-time":"2022-08-12T00:00:00Z","timestamp":1660262400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microorganisms"],"abstract":"<jats:p>Recently, numerous cases of monkeypox were reported from several non-endemic countries in Europe, North America, and Oceania, suggesting an unusual and alarming public health issue, particularly considering that the disease is not directly related to human or animal travels. Attention is currently being drawn to this phenomenon since more than 70% of the global population is no longer vaccinated against smallpox. Indeed, the smallpox vaccination also confers some indirect degree of protection against other poxviruses, including monkeypox. We performed a narrative review to describe the existing literature with regard to monkeypox using the MEDLINE, EMBASE, and Scopus databases. This review aims to provide updated evidence of findings on the epidemiology, clinical features, diagnosis, management, and prevention of monkeypox, also considering the concurrent zoonotic pandemic caused by the COVID-19 coronavirus, SARS-CoV-2.<\/jats:p>","DOI":"10.3390\/microorganisms10081633","type":"journal-article","created":{"date-parts":[[2022,8,15]],"date-time":"2022-08-15T03:33:20Z","timestamp":1660534400000},"page":"1633","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":68,"title":["Human Monkeypox: A Comprehensive Narrative Review and Analysis of the Public Health Implications"],"prefix":"10.3390","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3453-5647","authenticated-orcid":false,"given":"Francesco","family":"Di Gennaro","sequence":"first","affiliation":[{"name":"Clinic of Infectious Diseases, University of Bari, University Hospital Policlinico, 70121 Bari, 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Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0652-0520","authenticated-orcid":false,"given":"Andrea","family":"Silenzi","sequence":"additional","affiliation":[{"name":"General Directorate of Health Prevention, Ministry of Health, 00144 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Antunes","sequence":"additional","affiliation":[{"name":"Department of Surgery, Catholic University of Mozambique, Beira 13016, Mozambique"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annalisa","family":"Saracino","sequence":"additional","affiliation":[{"name":"Clinic of Infectious Diseases, University of Bari, University Hospital Policlinico, 70121 Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4833-7118","authenticated-orcid":false,"given":"Davide Fiore","family":"Bavaro","sequence":"additional","affiliation":[{"name":"Clinic of Infectious Diseases, University of Bari, University Hospital Policlinico, 70121 Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pinar","family":"Soysal","sequence":"additional","affiliation":[{"name":"Department of Geriatric Medicine, Faculty of Medicine, Bezmialem Vakif University, Istanbul 34093, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5276-2603","authenticated-orcid":false,"given":"Francesco Vladimiro","family":"Segala","sequence":"additional","affiliation":[{"name":"Clinic of Infectious Diseases, University of Bari, University Hospital Policlinico, 70121 Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurie","family":"Butler","sequence":"additional","affiliation":[{"name":"Faculty of Science and Engineering, Anglia Ruskin University, Cambridge CB1 1PT, 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University, Cambridge CB1 1PT, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emanuele","family":"Nicastri","sequence":"additional","affiliation":[{"name":"National Institute for Infectious Diseases, Lazzaro Spallanzani, IRCCS, Via Portuense, 292, 00149 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4122-0774","authenticated-orcid":false,"given":"Damiano","family":"Pizzol","sequence":"additional","affiliation":[{"name":"Italian Agency for Development Cooperation, 00135 Khartoum, Sudan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lee","family":"Smith","sequence":"additional","affiliation":[{"name":"Centre for Health Performance and Wellbeing, Anglia Ruskin University, Cambridge CB1 1PT, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,8,12]]},"reference":[{"key":"ref_1","first-page":"1027","article-title":"Human 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