{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T17:23:29Z","timestamp":1793035409407,"version":"4.5.0"},"reference-count":79,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2023,1,30]],"date-time":"2023-01-30T00:00:00Z","timestamp":1675036800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"industry research programs of Rospotrebnadzor for the period 2021\u20132025","award":["AAAA-A21-121011990061-3"],"award-info":[{"award-number":["AAAA-A21-121011990061-3"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microorganisms"],"abstract":"<jats:p>Salmonella enterica is an important foodborne pathogen worldwide. Ciprofloxacin and extended-spectrum cephalosporins are the common first-line antimicrobial drugs for the treatment of salmonellosis, antimicrobial resistance genes for which are mostly transferred via plasmids. The goal of this work was to perform genomic analysis of plasmids from foodborne S. enterica isolates obtained in Russia based on whole-genome sequencing. In the current study, 11 multidrug-resistant samples isolated in 2021 from 8 regions of Russia were selected based on their resistance to ciprofloxacin and third-generation cephalosporins (CIP-3rd). Whole-genome short-read sequencing (WGS) was performed for all isolates; the samples belonged to five different sequence types (ST32, ST469, ST11, ST142, and ST548) which had different profiles of antimicrobial resistance (AMR) and virulence genes. We have performed additional long-read sequencing of four representative S. enterica isolates, which showed that they carried pESI-like megaplasmids of 202\u2013280 kb length harboring extended-spectrum \u03b2-lactamase genes, fluoroquinolone, tetracycline, and aminoglycosides resistance genes, as well as several virulence determinants. We believe that the WGS data obtained will greatly facilitate further studies of foodborne S. enterica isolates epidemiology in terms of their self-transmissible plasmid composition that mediated antimicrobial resistance and virulence determinants conferring selective advantages of this important bacterial pathogen.<\/jats:p>","DOI":"10.3390\/microorganisms11020347","type":"journal-article","created":{"date-parts":[[2023,1,30]],"date-time":"2023-01-30T09:18:21Z","timestamp":1675070301000},"page":"347","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Plasmid Composition, Antimicrobial Resistance and Virulence Genes Profiles of Ciprofloxacin- and Third-Generation Cephalosporin-Resistant Foodborne Salmonella enterica Isolates from Russia"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0486-1353","authenticated-orcid":false,"given":"Anna","family":"Egorova","sequence":"first","affiliation":[{"name":"Central Research Institute of Epidemiology, Novogireevskaya Str., 3a, 111123 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7409-077X","authenticated-orcid":false,"given":"Andrey","family":"Shelenkov","sequence":"additional","affiliation":[{"name":"Central Research Institute of Epidemiology, Novogireevskaya Str., 3a, 111123 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5238-7900","authenticated-orcid":false,"given":"Konstantin","family":"Kuleshov","sequence":"additional","affiliation":[{"name":"Central Research Institute of Epidemiology, Novogireevskaya Str., 3a, 111123 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Kulikova","sequence":"additional","affiliation":[{"name":"Central Research Institute of Epidemiology, Novogireevskaya Str., 3a, 111123 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7049-4195","authenticated-orcid":false,"given":"Aleksey","family":"Chernyshkov","sequence":"additional","affiliation":[{"name":"Central Research Institute of Epidemiology, Novogireevskaya Str., 3a, 111123 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igor","family":"Manzeniuk","sequence":"additional","affiliation":[{"name":"Central Research Institute of Epidemiology, Novogireevskaya Str., 3a, 111123 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5646-538X","authenticated-orcid":false,"given":"Yulia","family":"Mikhaylova","sequence":"additional","affiliation":[{"name":"Central Research Institute of Epidemiology, Novogireevskaya Str., 3a, 111123 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasiliy","family":"Akimkin","sequence":"additional","affiliation":[{"name":"Central Research Institute of Epidemiology, Novogireevskaya Str., 3a, 111123 Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"529","DOI":"10.3934\/microbiol.2017.3.529","article-title":"Foodborne pathogens","volume":"3","author":"Bintsis","year":"2017","journal-title":"AIMS Microbiol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.cofs.2021.01.006","article-title":"Burden of foodborne diseases: Think global, act local","volume":"39","author":"Pires","year":"2021","journal-title":"Curr. Opin. Food Sci."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"29819","DOI":"10.3402\/fnr.v60.29819","article-title":"Public health implications of microbial food safety and foodborne diseases in developing countries","volume":"60","author":"Odeyemi","year":"2016","journal-title":"Food Nutr. Res."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"106","DOI":"10.3390\/hygiene1030010","article-title":"Trends of Major Foodborne Outbreaks in the European Union during the Years 2015\u20132019","volume":"1","author":"Schirone","year":"2021","journal-title":"Hygiene"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"e175","DOI":"10.1017\/S0950268822001558","article-title":"Geographical distribution and space-time clustering of human illnesses with major Salmonella serotypes in Florida, USA, 2017\u20132018","volume":"150","author":"Li","year":"2022","journal-title":"Epidemiol. Infect."},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Rakitin, A.L., Yushina, Y.K., Zaiko, E.V., Bataeva, D.S., Kuznetsova, O.A., Semenova, A.A., Ermolaeva, S.A., Beletskiy, A.V., Kolganova, T.V., and Mardanov, A.V. (2021). Evaluation of Antibiotic Resistance of Salmonella Serotypes and Whole-Genome Sequencing of Multiresistant Strains Isolated from Food Products in Russia. Antibiotics, 11.","DOI":"10.3390\/antibiotics11010001"},{"key":"ref_7","first-page":"e000365","article-title":"Molecular epidemiology of Salmonella Infantis in Europe: Insights into the success of the bacterial host and its parasitic pESI-like megaplasmid","volume":"6","author":"Alba","year":"2020","journal-title":"Microb. Genom."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.4315\/0362-028X-71.8.1685","article-title":"Prevalence and characterization of Salmonella in bovine lymph nodes potentially destined for use in ground beef","volume":"71","author":"Arthur","year":"2008","journal-title":"J. Food Prot."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"108893","DOI":"10.1016\/j.ijfoodmicro.2020.108893","article-title":"Nationwide surveillance on serotype distribution and antimicrobial resistance profiles of non-typhoidal Salmonella serovars isolated from food-producing animals in South Korea","volume":"335","author":"Mechesso","year":"2020","journal-title":"Int. J. Food Microbiol."},{"key":"ref_10","unstructured":"World Health Organization (2019). Global Antimicrobial Resistance Surveillance System (GLASS): Molecular Methods for Antimicrobial Resistance (AMR) Diagnostics to Enhance the Global Antimicrobial Resistance Surveillance System, World Health Organization."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"29","DOI":"10.3201\/eid2301.160771","article-title":"Estimated Incidence of Antimicrobial Drug-Resistant Nontyphoidal Salmonella Infections, United States, 2004\u20132012","volume":"23","author":"Medalla","year":"2016","journal-title":"Emerg. Infect. Dis."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1086\/379668","article-title":"Emergence of multidrug-resistant Salmonella enterica serotype Newport infections resistant to expanded-spectrum cephalosporins in the United States","volume":"188","author":"Gupta","year":"2003","journal-title":"J. Infect. Dis."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"3359","DOI":"10.1128\/JCM.42.7.3359-3362.2004","article-title":"Extended-spectrum-beta-lactamase (TEM-52)-producing strains of Salmonella enterica of various serotypes isolated in France","volume":"42","author":"Weill","year":"2004","journal-title":"J. Clin. Microbiol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.ijantimicag.2004.03.006","article-title":"Expanded-spectrum cephalosporin resistance in non-typhoid Salmonella","volume":"23","author":"Miriagou","year":"2004","journal-title":"Int. J. Antimicrob. Agents"},{"key":"ref_15","first-page":"751","article-title":"Overview of Molecular Typing Tools for The Characterization of Salmonella enterica in Malaysia","volume":"28","author":"Ngoi","year":"2015","journal-title":"Biomed. Environ. Sci."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"e00488-17","DOI":"10.1128\/AAC.00488-17","article-title":"Comparative Analysis of Extended-Spectrum-beta-Lactamase CTX-M-65-Producing Salmonella enterica Serovar Infantis Isolates from Humans, Food Animals, and Retail Chickens in the United States","volume":"61","author":"Tate","year":"2017","journal-title":"Antimicrob. Agents Chemother."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.3389\/fmicb.2017.01322","article-title":"Salmonella enterica serovar Infantis from Food and Human Infections, Switzerland, 2010\u20132015: Poultry-Related Multidrug Resistant Clones and an Emerging ESBL Producing Clonal Lineage","volume":"8","author":"Hindermann","year":"2017","journal-title":"Front. Microbiol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"108497","DOI":"10.1016\/j.ijfoodmicro.2019.108497","article-title":"Mega-plasmid found worldwide confers multiple antimicrobial resistance in Salmonella Infantis of broiler origin in Russia","volume":"319","author":"Bogomazova","year":"2020","journal-title":"Int. J. Food Microbiol."},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Egorova, A., Mikhaylova, Y., Saenko, S., Tyumentseva, M., Tyumentsev, A., Karbyshev, K., Chernyshkov, A., Manzeniuk, I., Akimkin, V., and Shelenkov, A. (2021). Comparative Whole-Genome Analysis of Russian Foodborne Multidrug-Resistant Salmonella Infantis Isolates. Microorganisms, 10.","DOI":"10.3390\/microorganisms10010089"},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Vazquez, X., Fernandez, J., Rodriguez-Lozano, J., Calvo, J., Rodicio, R., and Rodicio, M.R. (2022). Genomic Analysis of Two MDR Isolates of Salmonella enterica Serovar Infantis from a Spanish Hospital Bearing the bla(CTX-M-65) Gene with or without fosA3 in pESI-like Plasmids. Antibiotics, 11.","DOI":"10.3390\/antibiotics11060786"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"688614","DOI":"10.3389\/fmicb.2021.688614","article-title":"Serotyping, MLST, and Core Genome MLST Analysis of Salmonella enterica From Different Sources in China During 2004\u20132019","volume":"12","author":"Yan","year":"2021","journal-title":"Front. Microbiol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1089\/cmb.2012.0021","article-title":"SPAdes: A new genome assembly algorithm and its applications to single-cell sequencing","volume":"19","author":"Bankevich","year":"2012","journal-title":"J. Comput. Biol."},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Wick, R.R., Judd, L.M., Gorrie, C.L., and Holt, K.E. (2017). Unicycler: Resolving bacterial genome assemblies from short and long sequencing reads. PLoS Comput. Biol., 13.","DOI":"10.1371\/journal.pcbi.1005595"},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Shelenkov, A., Mikhaylova, Y., Yanushevich, Y., Samoilov, A., Petrova, L., Fomina, V., Gusarov, V., Zamyatin, M., Shagin, D., and Akimkin, V. (2020). Molecular Typing, Characterization of Antimicrobial Resistance, Virulence Profiling and Analysis of Whole-Genome Sequence of Clinical Klebsiella pneumoniae Isolates. Antibiotics, 9.","DOI":"10.3390\/antibiotics9050261"},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Tyumentseva, M., Mikhaylova, Y., Prelovskaya, A., Tyumentsev, A., Petrova, L., Fomina, V., Zamyatin, M., Shelenkov, A., and Akimkin, V. (2021). Genomic and Phenotypic Analysis of Multidrug-Resistant Acinetobacter baumannii Clinical Isolates Carrying Different Types of CRISPR\/Cas Systems. Pathogens, 10.","DOI":"10.3390\/pathogens10020205"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"12728","DOI":"10.1038\/s41598-021-91456-0","article-title":"AMRFinderPlus and the Reference Gene Catalog facilitate examination of the genomic links among antimicrobial resistance, stress response, and virulence","volume":"11","author":"Feldgarden","year":"2021","journal-title":"Sci. Rep."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"3895","DOI":"10.1128\/AAC.02412-14","article-title":"In silico detection and typing of plasmids using PlasmidFinder and plasmid multilocus sequence typing","volume":"58","author":"Carattoli","year":"2014","journal-title":"Antimicrob. Agents Chemother."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"2688","DOI":"10.1093\/bioinformatics\/btl446","article-title":"RAxML-VI-HPC: Maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models","volume":"22","author":"Stamatakis","year":"2006","journal-title":"Bioinformatics"},{"key":"ref_29","first-page":"e000146","article-title":"MentaLiST\u2014A fast MLST caller for large MLST schemes","volume":"4","author":"Feijao","year":"2018","journal-title":"Microb. Genom."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1093\/bioinformatics\/btw582","article-title":"PHYLOViZ 2.0: Providing scalable data integration and visualization for multiple phylogenetic inference methods","volume":"33","author":"Nascimento","year":"2017","journal-title":"Bioinformatics"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"2964","DOI":"10.1128\/JCM.39.8.2964-2966.2001","article-title":"Evaluation of VITEK 2 rapid identification and susceptibility testing system against gram-negative clinical isolates","volume":"39","author":"Ling","year":"2001","journal-title":"J. Clin. Microbiol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1073\/pnas.1416707112","article-title":"Patterns of genome evolution that have accompanied host adaptation in Salmonella","volume":"112","author":"Langridge","year":"2015","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"899062","DOI":"10.3389\/fmicb.2022.899062","article-title":"Genetic context of bla (CTX-M-55) and qnrS1 genes in a foodborne Salmonella enterica serotype Saintpaul isolate from China","volume":"13","author":"Li","year":"2022","journal-title":"Front. Microbiol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1128\/AAC.00645-08","article-title":"Variation in Salmonella enterica serovar typhi IncHI1 plasmids during the global spread of resistant typhoid fever","volume":"53","author":"Phan","year":"2009","journal-title":"Antimicrob. Agents Chemother."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"108941","DOI":"10.1016\/j.ijfoodmicro.2020.108941","article-title":"Virulence and resistance genes profiles and clonal relationships of non-typhoidal food-borne Salmonella strains isolated in Tunisia by whole genome sequencing","volume":"337","author":"Haendiges","year":"2021","journal-title":"Int. J. Food Microbiol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"4035","DOI":"10.1128\/AAC.46.12.4035-4037.2002","article-title":"Promoters P3, Pa\/Pb, P4, and P5 upstream from bla(TEM) genes and their relationship to beta-lactam resistance","volume":"46","author":"Lartigue","year":"2002","journal-title":"Antimicrob. Agents Chemother."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.jgar.2016.06.003","article-title":"Draft genome sequence of bla(TEM-1)-mediated cephalosporin-resistant Salmonella enterica serovar Typhi from bloodstream infection","volume":"7","author":"Shankar","year":"2016","journal-title":"J. Glob. Antimicrob. Resist."},{"key":"ref_38","doi-asserted-by":"crossref","unstructured":"Foley, S.L., Kaldhone, P.R., Ricke, S.C., and Han, J. (2021). Incompatibility Group I1 (IncI1) Plasmids: Their Genetics, Biology, and Public Health Relevance. Microbiol. Mol. Biol. Rev., 85.","DOI":"10.1128\/MMBR.00031-20"},{"key":"ref_39","doi-asserted-by":"crossref","unstructured":"Bell, E. (2021). Molecular Life Sciences: An Encyclopedic Reference, Springer.","DOI":"10.1007\/978-1-4614-6436-5"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.plasmid.2017.03.002","article-title":"Ordering the mob: Insights into replicon and MOB typing schemes from analysis of a curated dataset of publicly available plasmids","volume":"91","author":"Orlek","year":"2017","journal-title":"Plasmid"},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"European Food Safety Authority, and European Centre for Disease Prevention and Control (2021). The European Union One Health 2020 Zoonoses Report. EFSA J., 19, e06971.","DOI":"10.2903\/j.efsa.2021.6971"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1128\/JCM.02225-12","article-title":"Genetic analysis of non-hydrogen sulfide-producing Salmonella enterica serovar typhimurium and S. enterica serovar infantis isolates in Japan","volume":"51","author":"Sakano","year":"2013","journal-title":"J. Clin. Microbiol."},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"Elkenany, R., Elsayed, M.M., Zakaria, A.I., El-Sayed, S.A., and Rizk, M.A. (2019). Antimicrobial resistance profiles and virulence genotyping of Salmonella enterica serovars recovered from broiler chickens and chicken carcasses in Egypt. BMC Vet. Res., 15.","DOI":"10.1186\/s12917-019-1867-z"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.ijantimicag.2017.09.006","article-title":"Imported poultry meat as a source of extended-spectrum cephalosporin-resistant CMY-2-producing Salmonella Heidelberg and Salmonella Minnesota in the European Union, 2014\u20132015","volume":"51","author":"Campos","year":"2018","journal-title":"Int. J. Antimicrob. Agents"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1089\/mdr.2019.0384","article-title":"Characterization of Multidrug-Resistant Isolates of Salmonella enterica Serovars Heidelberg and Minnesota from Fresh Poultry Meat Imported to Portugal","volume":"27","author":"Silveira","year":"2021","journal-title":"Microb. Drug Resist."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"11058","DOI":"10.1038\/s41598-019-45838-0","article-title":"Genomic Features of High-Priority Salmonella enterica Serovars Circulating in the Food Production Chain, Brazil, 2000\u20132016","volume":"9","author":"Monte","year":"2019","journal-title":"Sci. Rep."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"109835","DOI":"10.1016\/j.ijfoodmicro.2022.109835","article-title":"First report from supermarket chicken meat and genomic characterization of colistin resistance mediated by mcr-1.1 in ESBL-producing, multidrug-resistant Salmonella Minnesota","volume":"379","author":"Habib","year":"2022","journal-title":"Int. J. Food Microbiol."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"2897","DOI":"10.1128\/JCM.02549-05","article-title":"Clonal emergence of extended-spectrum beta-lactamase (CTX-M-2)-producing Salmonella enterica serovar Virchow isolates with reduced susceptibilities to ciprofloxacin among poultry and humans in Belgium and France (2000 to 2003)","volume":"44","author":"Bertrand","year":"2006","journal-title":"J. Clin. Microbiol."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"5767","DOI":"10.1128\/JCM.42.12.5767-5773.2004","article-title":"Emergence of extended-spectrum-beta-lactamase (CTX-M-9)-producing multiresistant strains of Salmonella enterica serotype Virchow in poultry and humans in France","volume":"42","author":"Weill","year":"2004","journal-title":"J. Clin. Microbiol."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1292\/jvms.11-0488","article-title":"Emergence of Salmonella enterica serovar infantis harboring IncI1 plasmid with bla(CTX-M-14) in a broiler farm in Japan","volume":"74","author":"Kameyama","year":"2012","journal-title":"J. Vet. Med. Sci."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.diagmicrobio.2019.04.003","article-title":"Emergent multidrug-resistant nontyphoidal Salmonella serovars isolated from poultry in Brazil coharboring bla(CTX-M-2) and qnrB or bla(CMY-2) in large plasmids","volume":"95","author":"Ferreira","year":"2019","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"764787","DOI":"10.3389\/fmicb.2021.764787","article-title":"Prevalence and Characteristics of Ceftriaxone-Resistant Salmonella in Children\u2019s Hospital in Hangzhou, China","volume":"12","author":"Shi","year":"2021","journal-title":"Front. Microbiol."},{"key":"ref_53","first-page":"123","article-title":"Amoxicillin\/Clavulanic Acid and Cefotaxime Resistance in Salmonella Minnesota and Salmonella Heidelberg from Broiler Chickens","volume":"5","author":"Rodrigues","year":"2017","journal-title":"Poult. Sci. J."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1128\/microbiolspec.ARBA-0014-2017","article-title":"Antimicrobial Resistance in Nontyphoidal Salmonella","volume":"6","author":"McDermott","year":"2018","journal-title":"Microbiol. Spectr."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"104989","DOI":"10.1016\/j.meegid.2021.104989","article-title":"Multidrug resistance IncC plasmid carrying bla(CMY-97) in Shiga toxin-producing Escherichia coli ST215-H54 of ovine origin","volume":"93","author":"Furlan","year":"2021","journal-title":"Infect. Genet. Evol."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1080\/19440049.2016.1176450","article-title":"Occurrence of chloramphenicol in cereal straw in north-western Europe","volume":"33","author":"Nordkvist","year":"2016","journal-title":"Food Addit. Contam. Part A Chem. Anal. Control Expo. Risk Assess."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1007\/s00216-010-3724-6","article-title":"Evidence of natural occurrence of the banned antibiotic chloramphenicol in herbs and grass","volume":"397","author":"Berendsen","year":"2010","journal-title":"Anal. Bioanal. Chem."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/S0377-1237(07)80136-5","article-title":"Reemergence of Chloramphenicol Sensitivity in Enteric Fever","volume":"63","author":"Bhatia","year":"2007","journal-title":"Med. J. Armed Forces India"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1099\/00222615-48-4-367","article-title":"Increase in incidence of resistance to ampicillin, chloramphenicol and trimethoprim in clinical isolates of Salmonella serotype Typhimurium with investigation of molecular epidemiology and mechanisms of resistance","volume":"48","author":"Gallardo","year":"1999","journal-title":"J. Med. Microbiol."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.japr.2019.12.010","article-title":"Molecular characteristics of antimicrobial resistance determinants and integrons in Salmonella isolated from chicken meat in Korea","volume":"29","author":"Sin","year":"2020","journal-title":"J. Appl. Poult. Res."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"1715","DOI":"10.1128\/AAC.34.9.1715","article-title":"Clinical isolate of a porinless Salmonella typhi resistant to high levels of chloramphenicol","volume":"34","author":"Toro","year":"1990","journal-title":"Antimicrob. Agents Chemother."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"109063","DOI":"10.1016\/j.vetmic.2021.109063","article-title":"Mechanisms of polymyxin resistance induced by Salmonella typhimurium in vitro","volume":"257","author":"Li","year":"2021","journal-title":"Vet. Microbiol."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"3217","DOI":"10.2147\/IDR.S204618","article-title":"Sensitivity Pattern of Salmonella typhi and Paratyphi A Isolates to Chloramphenicol and other Anti-Typhoid Drugs: An In Vitro Study","volume":"12","author":"Patil","year":"2019","journal-title":"Infect. Drug Resist."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1258\/td.2008.070452","article-title":"Re-emerging chloramphenicol sensitivity and emerging low level ciprofloxacin resistance among Salmonella enterica serotype typhi isolates in North India","volume":"39","author":"Gupta","year":"2009","journal-title":"Trop. Doct."},{"key":"ref_65","doi-asserted-by":"crossref","unstructured":"Lerminiaux, N.A., MacKenzie, K.D., and Cameron, A.D.S. (2020). Salmonella Pathogenicity Island 1 (SPI-1): The Evolution and Stabilization of a Core Genomic Type Three Secretion System. Microorganisms, 8.","DOI":"10.3390\/microorganisms8040576"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"108956","DOI":"10.1016\/j.ijfoodmicro.2020.108956","article-title":"Whole-genome sequence analysis of Salmonella Infantis isolated from raw chicken meat samples and insights into pESI-like megaplasmid","volume":"337","author":"Kurekci","year":"2021","journal-title":"Int. J. Food Microbiol."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.3389\/fmicb.2020.01741","article-title":"Emergence of Multidrug-Resistant Salmonella enterica Subspecies enterica Serovar Infantis of Multilocus Sequence Type 2283 in German Broiler Farms","volume":"11","author":"Tomaso","year":"2020","journal-title":"Front. Microbiol."},{"key":"ref_68","doi-asserted-by":"crossref","unstructured":"Shaidullina, E., Shelenkov, A., Yanushevich, Y., Mikhaylova, Y., Shagin, D., Alexandrova, I., Ershova, O., Akimkin, V., Kozlov, R., and Edelstein, M. (2020). Antimicrobial Resistance and Genomic Characterization of OXA-48- and CTX-M-15-Co-Producing Hypervirulent Klebsiella pneumoniae ST23 Recovered from Nosocomial Outbreak. Antibiotics, 9.","DOI":"10.3390\/antibiotics9120862"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"384","DOI":"10.5455\/javar.2019.f358","article-title":"Detection of Salmonella pathogenicity island and Salmonella plasmid virulence genes in Salmonella Enteritidis originated from layer and broiler farms in Java Island","volume":"6","author":"Andesfha","year":"2019","journal-title":"J. Adv. Vet. Anim. Res."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"500","DOI":"10.3389\/fcimb.2017.00500","article-title":"An Updated View on the Rck Invasin of Salmonella: Still Much to Discover","volume":"7","author":"Mambu","year":"2017","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.micpath.2018.11.006","article-title":"Molecular analysis of virulence genes of Salmonella Infantis isolated from chickens and turkeys","volume":"126","author":"Akan","year":"2019","journal-title":"Microb. Pathog."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"2227","DOI":"10.1128\/AAC.01707-08","article-title":"Resistance plasmid families in Enterobacteriaceae","volume":"53","author":"Carattoli","year":"2009","journal-title":"Antimicrob. Agents Chemother."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1016\/j.ijmm.2011.09.003","article-title":"Plasmids in Gram negatives: Molecular typing of resistance plasmids","volume":"301","author":"Carattoli","year":"2011","journal-title":"Int. J. Med. Microbiol."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.plasmid.2004.06.006","article-title":"The complete nucleotide sequence of the resistance plasmid R478: Defining the backbone components of incompatibility group H conjugative plasmids through comparative genomics","volume":"52","author":"Gilmour","year":"2004","journal-title":"Plasmid"},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"4257","DOI":"10.1128\/JB.00232-07","article-title":"Multidrug-resistant Salmonella enterica serovar paratyphi A harbors IncHI1 plasmids similar to those found in serovar typhi","volume":"189","author":"Holt","year":"2007","journal-title":"J. Bacteriol."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.3389\/fmicb.2016.01566","article-title":"IncHI2 Plasmids Are Predominant in Antibiotic-Resistant Salmonella Isolates","volume":"7","author":"Chen","year":"2016","journal-title":"Front. Microbiol."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"562181","DOI":"10.3389\/fmicb.2020.562181","article-title":"Transferable Plasmids of Salmonella enterica Associated with Antibiotic Resistance Genes","volume":"11","author":"McMillan","year":"2020","journal-title":"Front. Microbiol."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.plasmid.2015.04.003","article-title":"The A to Z of A\/C plasmids","volume":"80","author":"Harmer","year":"2015","journal-title":"Plasmid"},{"key":"ref_79","doi-asserted-by":"crossref","unstructured":"Han, J., Lynne, A.M., David, D.E., Tang, H., Xu, J., Nayak, R., Kaldhone, P., Logue, C.M., and Foley, S.L. (2012). DNA sequence analysis of plasmids from multidrug resistant Salmonella enterica serotype Heidelberg isolates. 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