{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T12:35:53Z","timestamp":1791894953707,"version":"4.3.4"},"reference-count":75,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2023,7,12]],"date-time":"2023-07-12T00:00:00Z","timestamp":1689120000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microorganisms"],"abstract":"<jats:p>Since 1983, when the first report of a human Cryptosporidium spp. infection was published in Romania, and until now, many studies on cryptosporidiosis have been published in our country, but most of them are in the Romanian language and in national journals less accessible to international scientific databases. Although the infection was first recognized as a problem in children or immunocompromised people or more of a problem in low-income or underdeveloped global countries, we have shown in this review that it can also occur in people with normal immunological function and that the epidemiology of our country can provide a theoretical basis for the formulation of a Cryptosporidium spp. prevention strategy. In addition, 9.1% of healthy children and 73% of immunocompromised children were observed to have Cryptosporidium spp. infections. Higher rates have also been reported in immunocompromised adults (1.8\u201350%). Analyzing the prevalence of Cryptosporidium spp. infection in animals, we found values of 28.52% in cattle, 18% in buffalo calves, between 27.8 and 60.4% in pigs, 52.7% in dogs, and 29.4% in cats. Furthermore, in Romania, the burden of cryptosporidiosis, including acute infections and long-term sequelae, is currently unknown.<\/jats:p>","DOI":"10.3390\/microorganisms11071793","type":"journal-article","created":{"date-parts":[[2023,7,13]],"date-time":"2023-07-13T01:52:25Z","timestamp":1689213145000},"page":"1793","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Epidemiology of Cryptosporidium Infection in Romania: A Review"],"prefix":"10.3390","volume":"11","author":[{"given":"Gheorghe","family":"D\u0103r\u0103bu\u0219","sequence":"first","affiliation":[{"name":"Discipline of Parasitology, Faculty of Veterinary Medicine, University of Life Sciences King Michael I, 300645 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Alina","family":"Lupu","sequence":"additional","affiliation":[{"name":"Discipline of Parasitology, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300645 Timisoara, Romania"},{"name":"Center for Diagnosis and Study of Parasitic Diseases, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narcisa","family":"Mederle","sequence":"additional","affiliation":[{"name":"Discipline of Parasitology, Faculty of Veterinary Medicine, University of Life Sciences King Michael I, 300645 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodica Georgiana","family":"D\u0103r\u0103bu\u0219","sequence":"additional","affiliation":[{"name":"Discipline of Parasitology, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300645 Timisoara, Romania"},{"name":"Center for Diagnosis and Study of Parasitic Diseases, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6057-882X","authenticated-orcid":false,"given":"Kalman","family":"Imre","sequence":"additional","affiliation":[{"name":"Discipline of Parasitology, Faculty of Veterinary Medicine, University of Life Sciences King Michael I, 300645 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2242-7764","authenticated-orcid":false,"given":"Ovidiu","family":"Mederle","sequence":"additional","affiliation":[{"name":"Discipline of Parasitology, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300645 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3004-463X","authenticated-orcid":false,"given":"Mirela","family":"Imre","sequence":"additional","affiliation":[{"name":"Discipline of Parasitology, Faculty of Veterinary Medicine, University of Life Sciences King Michael I, 300645 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6235-9076","authenticated-orcid":false,"given":"Ana Alexandra","family":"Paduraru","sequence":"additional","affiliation":[{"name":"Discipline of Parasitology, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300645 Timisoara, Romania"},{"name":"Center for Diagnosis and Study of Parasitic Diseases, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sorin","family":"Morariu","sequence":"additional","affiliation":[{"name":"Discipline of Parasitology, Faculty of Veterinary Medicine, University of Life Sciences King Michael I, 300645 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1094-3729","authenticated-orcid":false,"given":"Tudor Rares","family":"Olariu","sequence":"additional","affiliation":[{"name":"Discipline of Parasitology, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300645 Timisoara, Romania"},{"name":"Center for Diagnosis and Study of Parasitic Diseases, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,7,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1128\/mr.47.1.84-96.1983","article-title":"Cryptosporidiosis in animals and humans","volume":"47","author":"Tzipori","year":"1983","journal-title":"Microbiol. 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