{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T14:56:06Z","timestamp":1784040966624,"version":"3.55.0"},"reference-count":53,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2023,7,19]],"date-time":"2023-07-19T00:00:00Z","timestamp":1689724800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior\u2014Brasil","award":["001"],"award-info":[{"award-number":["001"]}]},{"name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior\u2014Brasil","award":["CB2017"],"award-info":[{"award-number":["CB2017"]}]},{"name":"ESR Strategic Science Initiatives Funding","award":["001"],"award-info":[{"award-number":["001"]}]},{"name":"ESR Strategic Science Initiatives Funding","award":["CB2017"],"award-info":[{"award-number":["CB2017"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microorganisms"],"abstract":"<jats:p>Antimicrobial resistance is increasing despite new treatments being employed, so novel strategies are required to ensure that bacterial infections remain treatable. Bacteriophages (phages; bacteria viruses) have the potential to be used as natural antimicrobial methods to control bacterial pathogens such as Salmonella spp. A Salmonella phage, Wara, was isolated from environmental water samples at the Suba\u00e9 River Basin, Salvador de Bahia, Brazil. The basin has environmental impacts in its main watercourses arising from the dumping of domestic and industrial effluents and agricultural and anthropological activities. The phage genome sequence was determined by Oxford Nanopore Technologies (ONT) MinION and Illumina HiSeq sequencing, and assembly was carried out by Racon (MinION) and Unicycler (Illumina, Illumina + MinION). The genome was annotated and compared to other Salmonella phages using various bioinformatics approaches. MinION DNA sequencing combined with Racon assembly gave the best complete genome sequence. Phylogenetic analysis revealed that Wara is a member of the Tequintavirus genus. A lack of lysogeny genes, antimicrobial resistance, and virulence genes indicated that Wara has therapeutic and biocontrol potential against Salmonella species in healthcare and agriculture.<\/jats:p>","DOI":"10.3390\/microorganisms11071837","type":"journal-article","created":{"date-parts":[[2023,7,19]],"date-time":"2023-07-19T21:20:14Z","timestamp":1689801614000},"page":"1837","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Molecular Characterization of Salmonella Phage Wara Isolated from River Water in Brazil"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3119-9302","authenticated-orcid":false,"given":"Danitza Xiomara","family":"Romero-Calle","sequence":"first","affiliation":[{"name":"Postgraduate Program in Biotechnology, State University of Feira de Santana (UEFS), Av. Transnordestina S\/N, Feira de Santana 44036-900, Brazil"},{"name":"Molecular and Computational Biology of Fungi Laboratory, Department of Microbiology, Instituto de Ci\u00eancias Biol\u00f3gicas, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil"},{"name":"Department of Biological Sciences, Feira de Santana State University (UEFS), Feira de Santana 44036-900, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6394-7590","authenticated-orcid":false,"given":"Francisnei","family":"Pedrosa-Silva","sequence":"additional","affiliation":[{"name":"Laboratory of Chemistry, Function of Proteins and Peptides, Center for Biosciences and Biotechnology, Darcy Ribeiro North Fluminense State University (UENF), Campos dos Goytacazes 28013-602, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1477-5558","authenticated-orcid":false,"given":"Luiz Marcelo","family":"Ribeiro Tom\u00e9","sequence":"additional","affiliation":[{"name":"Molecular and Computational Biology of Fungi Laboratory, Department of Microbiology, Instituto de Ci\u00eancias Biol\u00f3gicas, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5521-6448","authenticated-orcid":false,"given":"Vagner","family":"Fonseca","sequence":"additional","affiliation":[{"name":"General Coordination of Public Health Laboratories\/Secretariat of Health Surveillance, Ministry of Health, Bras\u00edlia 70800-400, Brazil"},{"name":"Laboratory of Cellular and Molecular Genetics, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raquel","family":"Guimar\u00e3es Benevides","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Biotechnology, State University of Feira de Santana (UEFS), Av. 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Life Sci."},{"key":"ref_3","unstructured":"Tondo, E., and Ritter, A. (2012). Salmonella: Classification, Genetics and Disease Outbreaks, Nova Science Publishers, Inc."},{"key":"ref_4","unstructured":"(2023, May 08). World Health Statistics. Available online: https:\/\/www.who.int\/data\/gho\/publications\/world-health-statistics."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"i939","DOI":"10.1136\/bmj.i939","article-title":"Global Prevalence of Antibiotic Resistance in Paediatric Urinary Tract Infections Caused by Escherichia Coli and Association with Routine Use of Antibiotics in Primary Care: Systematic Review and Meta-Analysis","volume":"352","author":"Bryce","year":"2016","journal-title":"BMJ"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"2153","DOI":"10.1007\/s11274-014-1655-7","article-title":"Natural Solution to Antibiotic Resistance: Bacteriophages \u2018The Living Drugs\u2019","volume":"30","author":"Jassim","year":"2014","journal-title":"World J. Microbiol. Biotechnol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1038\/nrmicro.2017.61","article-title":"Pseudomonas Predators: Understanding and Exploiting Phage\u2013Host Interactions","volume":"15","author":"Hendrix","year":"2017","journal-title":"Nat. Rev. Microbiol."},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Romero-Calle, D., Guimar\u00e3es Benevides, R., G\u00f3es-Neto, A., and Billington, C. (2019). Bacteriophages as Alternatives to Antibiotics in Clinical Care. Antibiotics, 8.","DOI":"10.3390\/antibiotics8030138"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1089\/phage.2021.0013","article-title":"Phage Annotation Guide: Guidelines for Assembly and High-Quality Annotation","volume":"2","author":"Turner","year":"2021","journal-title":"Phage"},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Gibb, B., Hyman, P., and Schneider, C. (2021). The Many Applications of Engineered Bacteriophages\u2014An Overview. Pharmaceuticals, 14.","DOI":"10.3390\/ph14070634"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1128\/CMR.00075-13","article-title":"Whole-Genome Sequencing in Outbreak Analysis","volume":"28","author":"Gilchrist","year":"2015","journal-title":"Clin. Microbiol. Rev."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"130","DOI":"10.4161\/bact.1.3.17629","article-title":"Phage-Based Biocontrol Strategies to Reduce Foodborne Pathogens in Foods","volume":"1","author":"Goodridge","year":"2011","journal-title":"Bacteriophage"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.ijfoodmicro.2013.05.009","article-title":"Use of a Bacteriophage Cocktail to Control Salmonella in Food and the Food Industry","volume":"165","author":"Spricigo","year":"2013","journal-title":"Int. J. Food Microbiol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1089\/fpd.2013.1600","article-title":"Isolation, Characterization, and Application of Bacteriophages for Salmonella Spp. Biocontrol in Pigs","volume":"11","author":"Albino","year":"2014","journal-title":"Foodborne Pathog. Dis."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"4836","DOI":"10.3390\/v7082847","article-title":"Bio-Control of Salmonella Enteritidis in Foods Using Bacteriophages","volume":"7","author":"Bao","year":"2015","journal-title":"Viruses"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.ijfoodmicro.2015.04.025","article-title":"Reduction of Salmonella on Chicken Meat and Chicken Skin by Combined or Sequential Application of Lytic Bacteriophage with Chemical Antimicrobials","volume":"207","author":"Sukumaran","year":"2015","journal-title":"Int. J. Food Microbiol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1080\/09583157.2015.1125447","article-title":"Application of a Virulent Bacteriophage Cocktail Leads to Reduction of Salmonella enterica Serovar Enteritidis Counts in Processed Meat Products","volume":"26","author":"Galarce","year":"2016","journal-title":"Biocontrol Sci. Technol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1038\/nrmicro3096","article-title":"Revenge of the Phages: Defeating Bacterial Defences","volume":"11","author":"Samson","year":"2013","journal-title":"Nat. Rev. Microbiol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"eaar4120","DOI":"10.1126\/science.aar4120","article-title":"Systematic Discovery of Antiphage Defense Systems in the Microbial Pangenome","volume":"359","author":"Doron","year":"2018","journal-title":"Science"},{"key":"ref_20","first-page":"137","article-title":"Caracteriza\u00e7\u00e3o de metais pesados das \u00e1guas superficiais da bacia do Rio Suba\u00e9 (Bahia)","volume":"28","year":"2015","journal-title":"Geochim. Bras."},{"key":"ref_21","unstructured":"Pirui, M., and Curso, R.R. (2022). Los Bacteri\u00f3fagos: Del Genoma al Metagenoma, FIBA Fundaci\u00f3n para Investigaciones Biol\u00f3gicas Aplicadas."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1111\/j.1574-6968.2006.00217.x","article-title":"Isolation and Characterization of Bacteriophages Infecting Salmonella spp.","volume":"258","author":"Billington","year":"2006","journal-title":"FEMS Microbiol. Lett."},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Khan Mirzaei, M., and Nilsson, A.S. (2015). Isolation of Phages for Phage Therapy: A Comparison of Spot Tests and Efficiency of Plating Analyses for Determination of Host Range and Efficacy. PLoS ONE, 10.","DOI":"10.1371\/journal.pone.0118557"},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Romero-Calle, D.X., Pedrosa-Silva, F., Tom\u00e9, L.M.R., Sousa, T.J., de Oliveira Santos, L.T.S., de Carvalho Azevedo, V.A., Brenig, B., Benevides, R.G., Venancio, T.M., and Billington, C. (2022). Hybrid Genomic Analysis of Salmonella enterica Serovar Enteritidis SE3 Isolated from Polluted Soil in Brazil. Microorganisms, 11.","DOI":"10.3390\/microorganisms11010111"},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Tom\u00e9, L.M.R., da Silva, F.F., Fonseca, P.L.C., Mendes-Pereira, T., Azevedo, V.A.d.C., Brenig, B., Badotti, F., and G\u00f3es-Neto, A. (2022). Hybrid Assembly Improves Genome Quality and Completeness of Trametes Villosa CCMB561 and Reveals a Huge Potential for Lignocellulose Breakdown. J. Fungi, 8.","DOI":"10.3390\/jof8020142"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1101\/gr.215087.116","article-title":"Canu: Scalable and Accurate Long-Read Assembly via Adaptive k-Mer Weighting and Repeat Separation","volume":"27","author":"Koren","year":"2017","journal-title":"Genome Res"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1038\/s41587-019-0072-8","article-title":"Assembly of Long, Error-Prone Reads Using Repeat Graphs","volume":"37","author":"Kolmogorov","year":"2019","journal-title":"Nat. Biotechnol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1101\/gr.214270.116","article-title":"Fast and Accurate de Novo Genome Assembly from Long Uncorrected Reads","volume":"27","author":"Vaser","year":"2017","journal-title":"Genome Res."},{"key":"ref_29","unstructured":"Li, H. (2013). Aligning Sequence Reads, Clone Sequences and Assembly Contigs with BWA-MEM. arXiv."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1089\/cmb.2012.0021","article-title":"SPAdes: A New Genome Assembly Algorithm and Its Applications to Single-Cell Sequencing","volume":"19","author":"Bankevich","year":"2012","journal-title":"J. Comput. Biol."},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Wick, R.R., Judd, L.M., Gorrie, C.L., and Holt, K.E. (2017). Unicycler: Resolving Bacterial Genome Assemblies from Short and Long Sequencing Reads. PLoS Comput. Biol., 13.","DOI":"10.1371\/journal.pcbi.1005595"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1093\/bioinformatics\/btt086","article-title":"QUAST: Quality Assessment Tool for Genome Assemblies","volume":"29","author":"Gurevich","year":"2013","journal-title":"Bioinformatics"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"2068","DOI":"10.1093\/bioinformatics\/btu153","article-title":"Prokka: Rapid Prokaryotic Genome Annotation","volume":"30","author":"Seemann","year":"2014","journal-title":"Bioinformatics"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1038\/s41587-020-00774-7","article-title":"CheckV Assesses the Quality and Completeness of Metagenome-Assembled Viral Genomes","volume":"39","author":"Nayfach","year":"2021","journal-title":"Nat. Biotechnol."},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Yukgehnaish, K., Rajandas, H., Parimannan, S., Manickam, R., Marimuthu, K., Petersen, B., Clokie, M.R.J., Millard, A., and Sicheritz-Pont\u00e9n, T. (2022). PhageLeads: Rapid Assessment of Phage Therapeutic Suitability Using an Ensemble Machine Learning Approach. Viruses, 14.","DOI":"10.3390\/v14020342"},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Alikhan, N.-F., Petty, N.K., Ben Zakour, N.L., and Beatson, S.A. (2011). BLAST Ring Image Generator (BRIG): Simple Prokaryote Genome Comparisons. BMC Genom., 12.","DOI":"10.1186\/1471-2164-12-402"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1038\/s41587-019-0100-8","article-title":"Taxonomic Assignment of Uncultivated Prokaryotic Virus Genomes Is Enabled by Gene-Sharing Networks","volume":"37","author":"Bolduc","year":"2019","journal-title":"Nat. Biotechnol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1609\/icwsm.v3i1.13937","article-title":"Gephi: An Open Source Software for Exploring and Manipulating Networks","volume":"3","author":"Bastian","year":"2009","journal-title":"Proc. Int. AAAI Conf. Web Soc. Media"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"3691","DOI":"10.1093\/bioinformatics\/btv421","article-title":"Roary: Rapid Large-Scale Prokaryote Pan Genome Analysis","volume":"31","author":"Page","year":"2015","journal-title":"Bioinformatics"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1093\/molbev\/mst010","article-title":"MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability","volume":"30","author":"Katoh","year":"2013","journal-title":"Mol. Biol. Evol."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1093\/molbev\/msu300","article-title":"IQ-TREE: A Fast and Effective Stochastic Algorithm for Estimating Maximum-Likelihood Phylogenies","volume":"32","author":"Nguyen","year":"2015","journal-title":"Mol. Biol. Evol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"W256","DOI":"10.1093\/nar\/gkz239","article-title":"Interactive Tree of Life (ITOL) v4: Recent Updates and New Developments","volume":"47","author":"Letunic","year":"2019","journal-title":"Nucleic Acids Res."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"5114","DOI":"10.1038\/s41467-018-07641-9","article-title":"High Throughput ANI Analysis of 90K Prokaryotic Genomes Reveals Clear Species Boundaries","volume":"9","author":"Jain","year":"2018","journal-title":"Nat. Commun."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"2095","DOI":"10.1111\/1462-2920.14597","article-title":"The Genera of Bacteriophages and Their Receptors Are the Major Determinants of Host Range","volume":"21","author":"Gencay","year":"2019","journal-title":"Environ. Microbiol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1128\/JVI.02262-13","article-title":"Insights into Bacteriophage T5 Structure from Analysis of Its Morphogenesis Genes and Protein Components","volume":"88","author":"Zivanovic","year":"2014","journal-title":"J. Virol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.ijfoodmicro.2017.11.009","article-title":"Isolation and Characterization of Polyvalent Bacteriophages Infecting Multi Drug Resistant Salmonella Serovars Isolated from Broilers in Egypt","volume":"266","author":"Mahmoud","year":"2018","journal-title":"Int. J. Food Microbiol."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"2536","DOI":"10.3382\/ps.2007-00250","article-title":"Salmonella Host Range of Bacteriophages That Infect Multiple Genera","volume":"86","author":"Bielke","year":"2007","journal-title":"Poult. Sci."},{"key":"ref_48","doi-asserted-by":"crossref","unstructured":"Torkashvand, N., Kamyab, H., Shahverdi, A.R., Khoshayand, M.R., and Sepehrizadeh, Z. (2023). Isolation, Characterization, and Genome Analysis of a Broad Host Range Salmonella Phage VB_SenS_TUMS_E4: A Candidate Bacteriophage for Biocontrol. Vet. Res. Commun.","DOI":"10.1007\/s11259-023-10105-1"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"111","DOI":"10.4161\/bact.1.2.14590","article-title":"Pros and Cons of Phage Therapy","volume":"1","author":"Abedon","year":"2011","journal-title":"Bacteriophage"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.3389\/fmicb.2016.01352","article-title":"More Is Better: Selecting for Broad Host Range Bacteriophages","volume":"7","author":"Ross","year":"2016","journal-title":"Front. Microbiol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"e00301-20","DOI":"10.1128\/MRA.00301-20","article-title":"Complete Genome Sequences of Five Salmonella Enterica Phages, NBSal001, NBSal002, NBSal003, NBSal004, and NBSal005","volume":"9","author":"Llanos","year":"2020","journal-title":"Microbiol. Resour. Announc."},{"key":"ref_52","doi-asserted-by":"crossref","unstructured":"Rivera, D., Moreno-Switt, A.I., Denes, T.G., Hudson, L.K., Peters, T.L., Samir, R., Aziz, R.K., Noben, J.-P., Wagemans, J., and Due\u00f1as, F. (2022). Novel Salmonella Phage, VB_Sen_STGO-35-1, Characterization and Evaluation in Chicken Meat. Microorganisms, 10.","DOI":"10.3390\/microorganisms10030606"},{"key":"ref_53","doi-asserted-by":"crossref","unstructured":"Sattar, S., Ullah, I., Khanum, S., Bailie, M., Shamsi, B., Ahmed, I., Abbas Shah, T., Javed, S., Ghafoor, A., and Pervaiz, A. (2022). Genome Analysis and Therapeutic Evaluation of a Novel Lytic Bacteriophage of Salmonella Typhimurium: Suggestive of a New Genus in the Subfamily Vequintavirinae. Viruses, 14.","DOI":"10.3390\/v14020241"}],"container-title":["Microorganisms"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-2607\/11\/7\/1837\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T20:14:53Z","timestamp":1760127293000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-2607\/11\/7\/1837"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,19]]},"references-count":53,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2023,7]]}},"alternative-id":["microorganisms11071837"],"URL":"https:\/\/doi.org\/10.3390\/microorganisms11071837","relation":{},"ISSN":["2076-2607"],"issn-type":[{"value":"2076-2607","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,19]]}}}