{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T23:46:19Z","timestamp":1792799179817,"version":"4.5.0"},"reference-count":109,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T00:00:00Z","timestamp":1693612800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microorganisms"],"abstract":"<jats:p>The ongoing glomerular damage of infections is not limited to the most widely known form of post-streptococcal glomerulonephritis, which is today less common in the Western world; other forms of glomerulonephritis are associated with several bacterial, viral and parasitic pathogens. The mechanisms responsible range from the direct damage of glomerular cells to the formation and deposition of immunocomplexes to molecular mimicry to the secretion of superantigens. Similarly, in the course of glomerular disease, infections are more frequent than in the general population due to the loss of immunoglobulins in urine and the immunosuppressive agents used to treat the autoimmune disease that decrease the activity of the immune system. Recognizing this two-way link, understanding its pathogenetic mechanism, and identifying the most appropriate therapeutic choice are essential for the personalized management of patients. In this continuously developing field, this short review summarizes the current state of the art as support for physicians, who are increasingly involved in managing patients with glomerular disease and infections.<\/jats:p>","DOI":"10.3390\/microorganisms11092227","type":"journal-article","created":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T02:26:12Z","timestamp":1693794372000},"page":"2227","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Autoimmunity and Infection in Glomerular Disease"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-6348-8718","authenticated-orcid":false,"given":"Chiara","family":"Casuscelli","sequence":"first","affiliation":[{"name":"Unit of Nephrology and Dialysis, Department of Clinical and Experimental Medicine, A.O.U. \u201cG. 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Rev. Nephrol."},{"key":"ref_4","first-page":"340","article-title":"Renal Immunopathology Study Group of the Italian Society of N. Epidemiology of primary glomerulonephritis in the elderly. Report from the Italian Registry of Renal Biopsy","volume":"14","author":"Vendemia","year":"2001","journal-title":"J. Nephrol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1007\/s00467-006-0324-y","article-title":"HLA-DRB1* alleles in Egyptian children with post-streptococcal acute glomerulonephritis","volume":"22","author":"Bakr","year":"2007","journal-title":"Pediatr. Nephrol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1007\/s40620-013-0018-z","article-title":"New trends of an old disease: The acute post infectious glomerulonephritis at the beginning of the new millenium","volume":"27","author":"Stratta","year":"2014","journal-title":"J. Nephrol."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1111\/j.1651-2227.1996.tb14185.x","article-title":"HLA-DP antigens and post-streptococcal acute glomerulonephritis","volume":"85","author":"Mori","year":"1996","journal-title":"Acta Paediatr."},{"key":"ref_8","first-page":"99","article-title":"Acute Post-Streptococcal Glomerulonephritis in Adults: A Long-Term Study","volume":"48","author":"Lien","year":"1979","journal-title":"Q. J. Med."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"103073","DOI":"10.1016\/j.autrev.2022.103073","article-title":"Renal autoimmunity: The role of bacterial and viral infections, an extensive review","volume":"21","author":"Lavine","year":"2022","journal-title":"Autoimmun. Rev."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1111\/j.1523-1755.2005.00504.x","article-title":"Is the nephritogenic antigen in post-streptococcal glomerulonephritis pyrogenic exotoxin B (SPE B) or GAPDH?","volume":"68","author":"Batsford","year":"2005","journal-title":"Kidney Int."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1016\/j.humpath.2010.02.006","article-title":"Localization of nephritis-associated plasmin receptor in acute poststreptococcal glomerulonephritis","volume":"41","author":"Oda","year":"2010","journal-title":"Hum. Pathol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1046\/j.1523-1755.1998.00052.x","article-title":"Immunohistochemical and serological evidence for the role of streptococcal proteinase in acute post-streptococcal glomerulonephritis","volume":"54","author":"Cu","year":"1998","journal-title":"Kidney Int."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1080\/08830185.2020.1830083","article-title":"Acute post-streptococcal glomerulonephritis: Analysis of the pathogenesis","volume":"40","author":"Mosquera","year":"2021","journal-title":"Int. Rev. Immunol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"36455","DOI":"10.1038\/srep36455","article-title":"Presence of Streptococcus mutans strains harbouring the cnm gene correlates with dental caries status and IgA nephropathy conditions","volume":"6","author":"Misaki","year":"2016","journal-title":"Sci. Rep."},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Chen, H., Zhang, J., He, Y., Lv, Z., Liang, Z., Chen, J., Li, P., Liu, J., Yang, H., and Tao, A. (2022). Exploring the Role of Staphylococcus aureus in Inflammatory Diseases. Toxins, 14.","DOI":"10.3390\/toxins14070464"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"39","DOI":"10.2215\/CJN.05070516","article-title":"Staphylococcus Infection\u2013Associated GN\u2014Spectrum of IgA Staining and Prevalence of ANCA in a Single-Center Cohort","volume":"12","author":"Satoskar","year":"2017","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1097\/md.0b013e318161b0fc","article-title":"Acute postinfectious glomerulonephritis in the modern era: Experience with 86 adults and review of the literature","volume":"87","author":"Nasr","year":"2008","journal-title":"Medicine"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1093\/ndt\/17.7.1204","article-title":"Long-term prognosis of diffuse proliferative glomerulonephritis associated with infection in adults","volume":"17","author":"Moroni","year":"2002","journal-title":"Nephrol. Dial. Transplant."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1038\/nrmicro3161","article-title":"Adhesion, invasion and evasion: The many functions of the surface proteins of Staphylococcus aureus","volume":"12","author":"Foster","year":"2014","journal-title":"Nat. Rev. Microbiol."},{"key":"ref_20","unstructured":"Kidney Disease: Improving Global Outcomes (KDIGO) Glomerular Diseases Work Group (2021). KDIGO 2021 Clinical Practice Guideline for the Management of Glomerular Diseases. Kidney Int., 100, S1\u2013S276."},{"key":"ref_21","first-page":"40","article-title":"The presence of staphylococcal superantigens in nasal swabs and correlation with activity of granulomatosis with polyangiitis (GPA) in own material","volume":"36","author":"Wiatr","year":"2018","journal-title":"Clin. Exp. Rheumatol."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"3007","DOI":"10.1182\/blood-2012-03-416156","article-title":"Neutrophil extracellular traps mediate transfer of cytoplasmic neutrophil antigens to myeloid dendritic cells toward ANCA induction and associated autoimmunity","volume":"120","author":"Sangaletti","year":"2012","journal-title":"Blood"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1681\/ASN.V371351","article-title":"Secondary syphilis and the nephrotic syndrome","volume":"3","author":"Hunte","year":"1993","journal-title":"J. Am. Soc. Nephrol."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1111\/imj.15407","article-title":"Renal manifestations of syphilis","volume":"51","author":"Shettigar","year":"2021","journal-title":"Intern. Med. J."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1097\/DAD.0b013e3181e8b587","article-title":"The Immunopathobiology of Syphilis: The Manifestations and Course of Syphilis Are Determined by the Level of Delayed-Type Hypersensitivity","volume":"33","author":"Carlson","year":"2011","journal-title":"Am. J. Dermatopathol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/s42770-021-00675-0","article-title":"Helicobacter pylori: An up-to-date overview on the virulence and pathogenesis mechanisms","volume":"53","author":"Sharndama","year":"2022","journal-title":"Braz. J. Microbiol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1080\/0886022X.2020.1772295","article-title":"Helicobacter pylori infection is associated with elevated galactose-deficient IgA1 in IgA nephropathy","volume":"42","author":"Liu","year":"2020","journal-title":"Ren. Fail."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1016\/j.autrev.2017.10.009","article-title":"New insights in the pathogenesis of immunoglobulin A vasculitis (Henoch-Sch\u00f6nlein purpura)","volume":"16","author":"Heineke","year":"2017","journal-title":"Autoimmun. Rev."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.bj.2015.06.002","article-title":"Helicobacter pylori infection: An overview of bacterial virulence factors and pathogenesis","volume":"39","author":"Kao","year":"2016","journal-title":"Biomed. J."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1111\/j.1523-5378.2005.00346.x","article-title":"Immunity Markers in Patients with Helicobacter pylori Infection: Effect of Eradication","volume":"10","author":"Dore","year":"2005","journal-title":"Helicobacter"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1016\/j.ekir.2023.03.005","article-title":"Direct Kidney Involvement by Tropherymawhipplei","volume":"8","author":"Mignano","year":"2023","journal-title":"Kidney Int. Rep."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1016\/0016-5085(86)90398-7","article-title":"Whipple\u2019s disease with unusual clinical, bacteriologic, and immunologic findings","volume":"90","author":"Gupta","year":"1986","journal-title":"Gastroenterology"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1097\/00000441-195105000-00009","article-title":"Whipple\u2019s intestinal lipodystrophy: Its relationship to the rheumatic state","volume":"221","author":"Peterson","year":"1951","journal-title":"Am. J. Med. Sci."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1093\/cid\/ciy664","article-title":"Potential Role for Urine Polymerase Chain Reaction in the Diagnosis of Whipple\u2019s Disease","volume":"68","author":"Moter","year":"2019","journal-title":"Clin. Infect. Dis."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"1882","DOI":"10.1016\/S0140-6736(22)02039-6","article-title":"Bacterial infection possibly causing autoimmunity: Tropheryma whipplei and membranous nephropathy","volume":"400","author":"Wiech","year":"2022","journal-title":"Lancet"},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Guo, S., Pottanat, N.D., Herrmann, J.L., and Schamberger, M.S. (2022). Bartonella endocarditis and diffuse crescentic proliferative glomerulonephritis with a full-house pattern of immune complex deposition. BMC Nephrol., 23.","DOI":"10.1186\/s12882-022-02811-w"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1097\/IPC.0000000000000384","article-title":"Bartonella Endocarditis and Pauci-Immune Glomerulonephritis: A Case Report and Review of the Literature","volume":"24","author":"Raybould","year":"2016","journal-title":"Infect. Dis. Clin. Pract."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"2949","DOI":"10.1007\/s10067-022-06240-w","article-title":"Antineutrophil cytoplasmic antibodies in infective endocarditis: A case report and systematic review of the literature","volume":"41","author":"Kers","year":"2022","journal-title":"Clin. Rheumatol."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1097\/PAP.0b013e31826663d9","article-title":"Postinfectious glomerulonephritis","volume":"19","author":"Kambham","year":"2012","journal-title":"Adv. Anat. Pathol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1053\/hupa.2003.53","article-title":"Incidental healed postinfectious glomerulonephritis: A study of 1012 renal biopsy specimens examined by electron microscopy","volume":"34","author":"Haas","year":"2003","journal-title":"Hum. Pathol."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1123941","DOI":"10.3389\/fped.2023.1123941","article-title":"Clinical features of renal damage associated with Epstein-Barr virus infection in children","volume":"11","author":"Yang","year":"2023","journal-title":"Front. Pediatr."},{"key":"ref_42","doi-asserted-by":"crossref","unstructured":"Yadav, P., Tran, H., Ebegbe, R., Gottlieb, P., Wei, H., Lewis, R.H., Mumbey-Wafula, A., Kaplan, A., Kholdarova, E., and Spatz, L. (2011). Antibodies Elicited in Response to EBNA-1 May Cross-React with dsDNA. PLoS ONE, 6.","DOI":"10.1371\/journal.pone.0014488"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.molimm.2021.01.013","article-title":"Antibodies to an Epstein Barr Virus protein that cross-react with dsDNA have pathogenic potential","volume":"132","author":"Singh","year":"2021","journal-title":"Mol. Immunol."},{"key":"ref_44","first-page":"629","article-title":"IgA1-secreting cell lines from patients with IgA nephropathy produce aberrantly glycosylated IgA1","volume":"118","author":"Suzuki","year":"2008","journal-title":"J. Clin. Investig."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.2215\/CJN.09180816","article-title":"Viral-Associated GN: Hepatitis B and Other Viral Infections","volume":"12","author":"Kupin","year":"2017","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1111\/liv.13498","article-title":"Spectrum of hepatitis B and renal involvement","volume":"38","author":"Shah","year":"2018","journal-title":"Liver Int."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"18407","DOI":"10.1038\/s41598-021-98010-y","article-title":"Clinicopathological characteristics and prognosis of hepatitis B associated membranous nephropathy and idiopathic membranous nephropathy complicated with hepatitis B virus infection","volume":"11","author":"Wang","year":"2021","journal-title":"Sci. Rep."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"e600","DOI":"10.1542\/peds.2010-3137","article-title":"Universal Hepatitis B Vaccination Reduces Childhood Hepatitis B Virus\u2013Associated Membranous Nephropathy","volume":"128","author":"Liao","year":"2011","journal-title":"Pediatrics"},{"key":"ref_49","doi-asserted-by":"crossref","unstructured":"Yang, Y., Ma, Y.-P., Chen, D.-P., Zhuo, L., and Li, W.-G. (2016). A Meta-Analysis of Antiviral Therapy for Hepatitis B Virus-Associated Membranous Nephropathy. PLoS ONE, 11.","DOI":"10.1371\/journal.pone.0160437"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"12","DOI":"10.4066\/AMJ.2015.2568","article-title":"Immune mediated crescentic MPGN secondary to HBV infection: A rare presentation for a common infection","volume":"9","author":"Mareddy","year":"2016","journal-title":"Australas. Med. J."},{"key":"ref_51","first-page":"480","article-title":"Rheumatoid Factors in Hepatitis B and C Infections: Connecting Viruses, Autoimmunity, and Cancer","volume":"21","author":"Moll","year":"2019","journal-title":"Isr. Med. Assoc. J."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1159\/000348477","article-title":"Hepatitis C Virus-Associated Glomerulonephritis","volume":"181","author":"Tang","year":"2013","journal-title":"Contrib. Nephrol."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10238-018-0536-z","article-title":"Clinical practice: Hepatitis C virus infection, cryoglobulinemia and cryoglobulinemic vasculitis","volume":"19","author":"Dammacco","year":"2019","journal-title":"Clin. Exp. Med."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.jceh.2017.11.012","article-title":"Advances in HCV and Cryoglobulinemic Vasculitis in the Era of DAAs: Are We at the End of the Road?","volume":"8","author":"Bunchorntavakul","year":"2018","journal-title":"J. Clin. Exp. Hepatol."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"102923","DOI":"10.1016\/j.autrev.2021.102923","article-title":"Predictors of long-term cryoglobulinemic vasculitis outcomes after HCV eradication with direct-acting antivirals in the real-life","volume":"21","author":"Gragnani","year":"2022","journal-title":"Autoimmun. Rev."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"611317","DOI":"10.3389\/fmed.2020.611317","article-title":"Secondary Membranous Nephropathy. A Narrative Review","volume":"7","author":"Moroni","year":"2020","journal-title":"Front. Med."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"20","DOI":"10.3389\/fmed.2019.00020","article-title":"HCV-Associated Nephropathies in the Era of Direct Acting Antiviral Agents","volume":"6","author":"Angeletti","year":"2019","journal-title":"Front. Med."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1038\/nrneph.2015.216","article-title":"HIV-associated immune complex kidney disease","volume":"12","author":"Nobakht","year":"2016","journal-title":"Nat. Rev. Nephrol."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"177","DOI":"10.3389\/fmed.2018.00177","article-title":"Molecular Mechanisms of Injury in HIV-Associated Nephropathy","volume":"5","author":"Rednor","year":"2018","journal-title":"Front. Med."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"73","DOI":"10.2147\/HIV.S141978","article-title":"HIV-associated nephropathy: Links, risks and management","volume":"10","author":"Palau","year":"2018","journal-title":"HIV\/AIDS\u2014Res. Palliat. Care"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"1","DOI":"10.14740\/jocmr3235w","article-title":"HIV-Associated Nephropathy in Africa: Pathology, Clinical Presentation and Strategy for Prevention","volume":"10","author":"Husain","year":"2018","journal-title":"J. Clin. Med. Res."},{"key":"ref_62","first-page":"412","article-title":"Nephrotic syndrome due to lupus-like glomerulonephritis in an HIV-positive patient","volume":"75","author":"Wiegersma","year":"2017","journal-title":"Neth. J. Med."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1002\/ccr3.2955","article-title":"Successful treatment of HIV-associated lupus-like glomerulonephritis with mycophenolic acid","volume":"8","author":"Tiong","year":"2020","journal-title":"Clin. Case Rep."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.1093\/ndt\/gfv436","article-title":"Clinical characteristics and outcomes of HIV-associated immune complex kidney disease","volume":"31","author":"Booth","year":"2016","journal-title":"Nephrol. Dial. Transplant."},{"key":"ref_65","doi-asserted-by":"crossref","unstructured":"Charu, V., Andeen, N., Walavalkar, V., Lapasia, J., Kim, J.-Y., Lin, A., Sibley, R., Higgins, J., Troxell, M., and Kambham, N. (2020). Membranous nephropathy in patients with HIV: A report of 11 cases. BMC Nephrol., 21.","DOI":"10.1186\/s12882-020-02042-x"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1177\/039463201302600414","article-title":"Clinically-Irrelevant Positivity for Serum Proteinase 3-ANCA in HIV Disease","volume":"26","author":"Romano","year":"2013","journal-title":"Int. J. Immunopathol. Pharmacol."},{"key":"ref_67","first-page":"270","article-title":"ANCA seropositivity in HIV: A serological pitfall","volume":"63","author":"Jansen","year":"2005","journal-title":"Neth. J. Med."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"e55","DOI":"10.1053\/j.ajkd.2006.06.007","article-title":"The Uncertain Significance of Anti\u2013Glomerular Basement Membrane Antibody among HIV-Infected Persons with Kidney Disease","volume":"48","author":"Szczech","year":"2006","journal-title":"Am. J. Kidney Dis."},{"key":"ref_69","doi-asserted-by":"crossref","unstructured":"Wang, W.-J., Jia, X.-Y., Cui, Z., Chen, Y., Wang, W., Lou, J.-L., Zhao, M.-H., and Ying, S. (2020). The prevalence and immunological features of anti-glomerular basement membrane antibody in patients with HIV. BMC Nephrol., 21.","DOI":"10.1186\/s12882-020-02087-y"},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1097\/MD.0b013e31818ec711","article-title":"Acute viral infections in patients with systemic lupus erythematosus: Description of 23 cases and review of the literature","volume":"87","author":"Cuadrado","year":"2008","journal-title":"Medicine"},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"6577","DOI":"10.1021\/acs.biochem.6b00534","article-title":"DNA Binding and Cleavage by the Human Parvovirus B19 NS1 Nuclease Domain","volume":"55","author":"Sanchez","year":"2016","journal-title":"Biochemistry"},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1093\/infdis\/jiy614","article-title":"Parvovirus B19V Nonstructural Protein NS1 Induces Double-Stranded Deoxyribonucleic Acid Autoantibodies and End-Organ Damage in Nonautoimmune Mice","volume":"219","author":"Puttaraksa","year":"2019","journal-title":"J. Infect. Dis."},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"S47","DOI":"10.2215\/CJN.01060307","article-title":"Parvovirus B19 and the Kidney","volume":"2","author":"Waldman","year":"2007","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1034\/j.1600-0560.2002.291006.x","article-title":"Parvovirus B19 associated adult Henoch Sch\u00f6nlein purpura","volume":"29","author":"Cioc","year":"2002","journal-title":"J. Cutan. Pathol."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1002\/art.1780371122","article-title":"Wegener\u2019s granulomatosis and parvovirus B19 infection","volume":"37","author":"Nikkari","year":"1994","journal-title":"Arthritis Rheum."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1136\/jclinpath-2020-207023","article-title":"High burden of acute kidney injury in COVID-19 pandemic: Systematic review and meta-analysis","volume":"74","author":"Oliveira","year":"2021","journal-title":"J. Clin. Pathol."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1056\/NEJMc2011400","article-title":"Multiorgan and Renal Tropism of SARS-CoV-2","volume":"383","author":"Puelles","year":"2020","journal-title":"N. Engl. J. Med."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1080\/22221751.2020.1760144","article-title":"Isolation of infectious SARS-CoV-2 from urine of a COVID-19 patient","volume":"9","author":"Sun","year":"2020","journal-title":"Emerg. Microbes Infect."},{"key":"ref_79","doi-asserted-by":"crossref","unstructured":"P\u00e9rez, A., Torregrosa, I., D\u2019Marco, L., Juan, I., Terradez, L., Sol\u00eds, M.\u00c1., Moncho, F., Carda-Batalla, C., Forner, M.J., and Gorriz, J.L. (2021). IgA-Dominant Infection-Associated Glomerulonephritis Following SARS-CoV-2 Infection. Viruses, 13.","DOI":"10.3390\/v13040587"},{"key":"ref_80","doi-asserted-by":"crossref","unstructured":"Huang, Y., Li, X.J., Li, Y.Q., Dai, W., Shao, T., Liu, W.Y., Han, M., Xu, G., and Liu, L. (2020). Clinical and pathological findings of SARS-CoV-2 infection and concurrent IgA nephropathy: A case report. BMC Nephrol., 21.","DOI":"10.1186\/s12882-020-02163-3"},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"e239910","DOI":"10.1136\/bcr-2020-239910","article-title":"A child with Henoch-Schonlein purpura secondary to a COVID-19 infection","volume":"14","author":"AlGhoozi","year":"2021","journal-title":"BMJ Case Rep."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"2074","DOI":"10.1016\/j.ekir.2020.08.016","article-title":"IgA Vasculitis With Nephritis (Henoch\u2212Sch\u00f6nlein Purpura) in a COVID-19 Patient","volume":"5","author":"Suso","year":"2020","journal-title":"Kidney Int. Rep."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"102883","DOI":"10.1016\/j.autrev.2021.102883","article-title":"Rheumatological complications of COVID-19","volume":"20","author":"Zacharias","year":"2021","journal-title":"Autoimmun. Rev."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1016\/j.ekir.2020.08.012","article-title":"De Novo ANCA-Associated Vasculitis with Glomerulonephritis in COVID-19","volume":"5","author":"Uppal","year":"2020","journal-title":"Kidney Int. Rep."},{"key":"ref_85","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1007\/s00296-021-04914-3","article-title":"ANCA-associated vasculitis after COVID-19","volume":"41","author":"Duran","year":"2021","journal-title":"Rheumatol. Int."},{"key":"ref_86","first-page":"e15259","article-title":"A Rare Case of SARS-CoV-2-Induced Microscopic Polyangiitis","volume":"13","author":"Allena","year":"2021","journal-title":"Cureus"},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1016\/j.kint.2020.06.009","article-title":"Anti\u2013glomerular basement membrane disease during the COVID-19 pandemic","volume":"98","author":"Prendecki","year":"2020","journal-title":"Kidney Int."},{"key":"ref_88","doi-asserted-by":"crossref","unstructured":"Winkler, A., Zitt, E., Sprenger-Mahr, H., Soleiman, A., Cejna, M., and Lhotta, K. (2021). SARS-CoV-2 infection and recurrence of anti-glomerular basement disease: A case report. BMC Nephrol., 22.","DOI":"10.1186\/s12882-021-02275-4"},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"393","DOI":"10.2147\/IJNRD.S333894","article-title":"Temporal Clustering of Antiglomerular Basement Membrane Disease in COVID-19 Pandemic: A Case Series","volume":"14","author":"Sebastian","year":"2021","journal-title":"Int. J. Nephrol. Renov. Dis."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1038\/s41581-022-00558-z","article-title":"Kidney complications of parasitic diseases","volume":"18","author":"Daher","year":"2022","journal-title":"Nat. Rev. Nephrol."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"573735","DOI":"10.5402\/2013\/573735","article-title":"Incidence of Renal Involvement in Malaria in Children of Odisha","volume":"2013","author":"Padhi","year":"2013","journal-title":"ISRN Nephrol."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1007\/s00467-017-3785-2","article-title":"Infections and the kidney: A tale from the tropics","volume":"33","author":"Kamath","year":"2018","journal-title":"Pediatr. Nephrol."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3851\/IMP2975","article-title":"Hepatitis C Cure with Antiviral Therapy\u2014Benefits beyond the Liver","volume":"21","author":"Soriano","year":"2016","journal-title":"Antivir. Ther."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1038\/s41577-022-00816-y","article-title":"Glomerulonephritis: Immunopathogenesis and immunotherapy","volume":"23","author":"Anders","year":"2023","journal-title":"Nat. Rev. Immunol."},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"e157432","DOI":"10.1172\/jci.insight.157432","article-title":"JAK inhibitor blocks COVID-19 cytokine\u2013induced JAK\/STAT\/APOL1 signaling in glomerular cells and podocytopathy in human kidney organoids","volume":"7","author":"Nystrom","year":"2022","journal-title":"JCI Insight"},{"key":"ref_96","doi-asserted-by":"crossref","unstructured":"Rostaing, L., and Malvezzi, P. (2016). Steroid-Based Therapy and Risk of Infectious Complications. PLoS Med., 13.","DOI":"10.1371\/journal.pmed.1002025"},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1093\/clinids\/11.6.954","article-title":"Risk of Infectious Complications in Patients Taking Glucocorticosteroids","volume":"11","author":"Stuck","year":"1989","journal-title":"Clin. Infect. Dis."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"815","DOI":"10.2215\/CJN.12991117","article-title":"Glucocorticoids in the Treatment of Glomerular Diseases: Pitfalls and Pearls","volume":"13","author":"Ponticelli","year":"2018","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"ref_99","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1001\/jama.2022.5368","article-title":"Effect of Oral Methylprednisolone on Decline in Kidney Function or Kidney Failure in Patients with IgA Nephropathy: The TESTING Randomized Clinical Trial","volume":"327","author":"Lv","year":"2022","journal-title":"JAMA"},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.reuma.2014.09.003","article-title":"Severe Infections in Patients with Autoimmune Diseases Treated with Cyclophosphamide","volume":"11","author":"Cavallasca","year":"2015","journal-title":"Reumatol. Clin."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1007\/s11255-021-02973-w","article-title":"Cytomegalovirus infection in patients with glomerular diseases treated with cyclophosphamide: A single-center prospective study","volume":"54","author":"Eyupoglu","year":"2022","journal-title":"Int. Urol. Nephrol."},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1080\/23744235.2019.1648855","article-title":"Risk-stratified approach to anti-viral prophylaxis against cytomegalovirus disease in glomerulonephritis and renal vasculitis treated with potent immunosuppressants","volume":"51","author":"Lim","year":"2019","journal-title":"Infect. Dis."},{"key":"ref_103","first-page":"461","article-title":"Infectious complications of a rituximab-based immunosuppressive regimen in patients with glomerular disease","volume":"10","author":"Trivin","year":"2017","journal-title":"Clin. Kidney J."},{"key":"ref_104","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1681\/ASN.2012020181","article-title":"Rituximab in Idiopathic Membranous Nephropathy","volume":"23","author":"Ruggenenti","year":"2012","journal-title":"J. Am. Soc. Nephrol."},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"1664","DOI":"10.1001\/jama.2013.281115","article-title":"FDA: Increased HBV Reactivation Risk With Ofatumumab or Rituximab","volume":"310","author":"Mitka","year":"2013","journal-title":"JAMA"},{"key":"ref_106","doi-asserted-by":"crossref","unstructured":"Omair, M.A., Alahmadi, A., and Johnson, S.R. (2015). Safety and Effectiveness of Mycophenolate in Systemic Sclerosis. A Systematic Review. PLoS ONE, 10.","DOI":"10.1371\/journal.pone.0124205"},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/s40265-016-0683-z","article-title":"Efficacy and Safety of Tacrolimus versus Cyclophosphamide for Primary Membranous Nephropathy: A Meta-Analysis","volume":"77","author":"Zhu","year":"2017","journal-title":"Drugs"},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.autrev.2015.09.006","article-title":"Tacrolimus use in lupus nephritis: A systematic review and meta-analysis","volume":"15","author":"Hannah","year":"2016","journal-title":"Autoimmun. Rev."},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1097\/QCO.0000000000000279","article-title":"Infections associated with the use of eculizumab: Recommendations for prevention and prophylaxis","volume":"29","author":"Benamu","year":"2016","journal-title":"Curr. Opin. Infect. 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