{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:34:58Z","timestamp":1760150098434,"version":"build-2065373602"},"reference-count":16,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T00:00:00Z","timestamp":1695859200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"University of the Ryukyus Foundation"},{"name":"United Graduate School of Agricultural Sciences, Kagoshima University"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microorganisms"],"abstract":"<jats:p>Paracoccidioidomycosis ceti (PCM-C) is a chronic granulomatous keloidal dermatitis in cetaceans that has been reported worldwide and is caused by Paracoccidioides ceti. Serological cross-reactions among highly pathogenic fungal infections and related diseases have been reported. However, the true cross-reaction of antibodies against P. ceti has remained unknown due to the use of positive control sera from infected dolphins. This study aimed to re-evaluate antibodies from mechanically dislodged fungal cells in the infected tissue of a PCM-C case and demonstrate the actual cross-reaction. The results revealed a limited cross-reaction between PCM-C and paracoccidioidomycosis, while the antibodies did not react with other pathogens such as Coccidioides posadasii, Histoplasama capsulatum, and Arthrographis kalrae. Thus, the method for evaluation of the antibody against PCM-C is reliable, and there is potential for epidemiological study.<\/jats:p>","DOI":"10.3390\/microorganisms11102428","type":"journal-article","created":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T05:55:54Z","timestamp":1695880554000},"page":"2428","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Re-Evaluation of the Cross-Reactions of the Antibody against the Causative Agent for Paracoccidioidomycosis Ceti; Paracoccidioides ceti and the Related Fungal Species"],"prefix":"10.3390","volume":"11","author":[{"given":"Hikaru","family":"Kanegae","sequence":"first","affiliation":[{"name":"The United Graduate School of Agricultural Sciences, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7160-319X","authenticated-orcid":false,"given":"Igor Massahiro","family":"de Souza Suguiura","sequence":"additional","affiliation":[{"name":"Department of Pathological Sciences, State University of Londrina, P.O. Box 10011, Londrina 86057-970, PR, Brazil"},{"name":"Paran\u00e1 State Secretariat of Health, Department of Health Surveillance, 17th Health Region, Alameda Miguel Blasi, 76-Centro, Londrina 86010-070, PR, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rentaro","family":"Tashiro","sequence":"additional","affiliation":[{"name":"Graduate School of Agriculture, University of the Ryukyus, Sembaru 1, Nishihara-Cho, Nakagami-Gun 903-0213, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshihiro","family":"Konno","sequence":"additional","affiliation":[{"name":"The United Graduate School of Agricultural Sciences, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan"},{"name":"Graduate School of Agriculture, University of the Ryukyus, Sembaru 1, Nishihara-Cho, Nakagami-Gun 903-0213, Japan"},{"name":"Faculty of Agriculture, University of the Ryukyus, Sembaru 1, Nishihara-Cho, Nakagami-Gun 903-0213, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"De-Xing","family":"Hou","sequence":"additional","affiliation":[{"name":"The United Graduate School of Agricultural Sciences, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan"},{"name":"Faculty of Agriculture, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5240-4750","authenticated-orcid":false,"given":"Ayako","family":"Sano","sequence":"additional","affiliation":[{"name":"The United Graduate School of Agricultural Sciences, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan"},{"name":"Graduate School of Agriculture, University of the Ryukyus, Sembaru 1, Nishihara-Cho, Nakagami-Gun 903-0213, Japan"},{"name":"Faculty of Agriculture, University of the Ryukyus, Sembaru 1, Nishihara-Cho, Nakagami-Gun 903-0213, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Eto","sequence":"additional","affiliation":[{"name":"Faculty of Agriculture, University of the Ryukyus, Sembaru 1, Nishihara-Cho, Nakagami-Gun 903-0213, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiichi","family":"Ueda","sequence":"additional","affiliation":[{"name":"Okinawa Churashima Foundation, Aza Ishikawa 888, Motobu-Cho, Kunigami-Gun 905-0206, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Md. Amzad","family":"Hossain","sequence":"additional","affiliation":[{"name":"The United Graduate School of Agricultural Sciences, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan"},{"name":"Graduate School of Agriculture, University of the Ryukyus, Sembaru 1, Nishihara-Cho, Nakagami-Gun 903-0213, Japan"},{"name":"Faculty of Agriculture, University of the Ryukyus, Sembaru 1, Nishihara-Cho, Nakagami-Gun 903-0213, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,9,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Seyedmousavi, S., de Hoog, G.S., Guillot, J., and Verweij, P.E. (2018). 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