{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T22:14:11Z","timestamp":1767046451700,"version":"build-2065373602"},"reference-count":166,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2024,3,7]],"date-time":"2024-03-07T00:00:00Z","timestamp":1709769600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microorganisms"],"abstract":"<jats:p>Acute respiratory viruses (ARVs) are the leading cause of diseases in humans worldwide. High-risk individuals, including children and the elderly, could potentially develop severe illnesses that could result in hospitalization or death in the worst case. The most common ARVs are the Human respiratory syncytial virus, Human Metapneumovirus, Human Parainfluenza Virus, rhinovirus, coronaviruses (including SARS and MERS CoV), adenoviruses, Human Bocavirus, enterovirus (-D68 and 71), and influenza viruses. The olfactory deficits due to ARV infection are a common symptom among patients. This review provides an overview of the role of SARS-CoV-2 and other common ARVs in the development of human olfactory pathophysiology. We highlight the critical need to understand the signaling underlying the olfactory dysfunction and the development of therapeutics for this wide-ranging category of AVRs to restore the altered or loss of smell in affected patients.<\/jats:p>","DOI":"10.3390\/microorganisms12030540","type":"journal-article","created":{"date-parts":[[2024,3,7]],"date-time":"2024-03-07T11:33:06Z","timestamp":1709811186000},"page":"540","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["SARS-CoV-2 and Other Respiratory Viruses in Human Olfactory Pathophysiology"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8307-0220","authenticated-orcid":false,"given":"Serigne Fallou","family":"Wade","sequence":"first","affiliation":[{"name":"\u00c9cole Sup\u00e9rieure des Sciences Agricoles et de l\u2019Alimentation, Universit\u00e9 Amadou Makhtar MBOW, Rue 21x20, 2\u00e8me Arrondissement, P\u00f4le Urbain de Diamniadio, Dakar P.O. Box 45927, Senegal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3658-6245","authenticated-orcid":false,"given":"Abou Abdallah Malick","family":"Diouara","sequence":"additional","affiliation":[{"name":"Groupe de Recherche Biotechnologies Appliqu\u00e9es & Bioproc\u00e9d\u00e9s environnementaux (GRBA-BE), \u00c9cole Sup\u00e9rieure Polytechnique, Universit\u00e9 Cheikh Anta Diop, Dakar P.O. Box 5085, Senegal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Babacar","family":"Ngom","sequence":"additional","affiliation":[{"name":"\u00c9cole Sup\u00e9rieure des Sciences Agricoles et de l\u2019Alimentation, Universit\u00e9 Amadou Makhtar MBOW, Rue 21x20, 2\u00e8me Arrondissement, P\u00f4le Urbain de Diamniadio, Dakar P.O. Box 45927, Senegal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8247-4426","authenticated-orcid":false,"given":"Fatou","family":"Thiam","sequence":"additional","affiliation":[{"name":"Groupe de Recherche Biotechnologies Appliqu\u00e9es & Bioproc\u00e9d\u00e9s environnementaux (GRBA-BE), \u00c9cole Sup\u00e9rieure Polytechnique, Universit\u00e9 Cheikh Anta Diop, Dakar P.O. Box 5085, Senegal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ndongo","family":"Dia","sequence":"additional","affiliation":[{"name":"Virology Departement, Institut Pasteur de Dakar, 36, Avenue Pasteur, Dakar P.O. 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