{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T00:22:04Z","timestamp":1787962924081,"version":"build-2784847793"},"reference-count":45,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2024,3,15]],"date-time":"2024-03-15T00:00:00Z","timestamp":1710460800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Universidad de Buenos Aires, UBACyT","award":["UBACYT 20020150100223BA"],"award-info":[{"award-number":["UBACYT 20020150100223BA"]}]},{"name":"Universidad de Buenos Aires, UBACyT","award":["UBACYT 20020190100357BA"],"award-info":[{"award-number":["UBACYT 20020190100357BA"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microorganisms"],"abstract":"<jats:p>Since the Lymphogranuloma venereum (LGV) outbreak was first described in Buenos Aires in 2017, the detected strains presented peculiar characteristics. Our goal was to increase the understanding of the strains involved in the LGV outbreak in Argentina. We characterized the ompA gene sequences, using Sanger sequencing, of 88 LGV strains from 239 symptomatic patients in Buenos Aires enrolled between 2017 and 2019, and selected 20 C. trachomatis strains for further characterization using Multilocus Sequence Typing (MLST). Following the ompA gene analysis of the 88 LGV strains, we detected 43% L2b, 31% L1-like, and 26% L2. Among the 38 L2b samples analyzed, there were 7 distinct sequences, 3 of them not previously reported (L2bv12, L2bv13, and L2bv14). Additionally, we detected a strain with a new mutation (AM884176.1:g.59122A&gt;T) found in the position defining L2 or L2b, proposed as L2i. Using MLST, five different sequence types (STs) were detected, including the ST2 (corresponding to the L1-like strains) and a new one (ST60). ST58 was associated with the concomitant presence of another STI and HIV. A high genetic diversity in C. trachomatis LGV strains in Argentina was observed in a short period of time, with a relatively low number of samples from a limited geographical area.<\/jats:p>","DOI":"10.3390\/microorganisms12030587","type":"journal-article","created":{"date-parts":[[2024,3,15]],"date-time":"2024-03-15T12:02:39Z","timestamp":1710504159000},"page":"587","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["ompA Sequencing and Multilocus Sequence Typing of Lymphogranuloma Venereum Cases in Buenos Aires Reveal New Chlamydia trachomatis Genotypes"],"prefix":"10.3390","volume":"12","author":[{"given":"Karina Andrea","family":"B\u00fcttner","sequence":"first","affiliation":[{"name":"Universidad de Buenos Aires, Facultad de Farmacia y Bioqu\u00edmica, Microbiolog\u00eda Cl\u00ednica, Buenos Aires C1113AAD, Argentina"},{"name":"Universidad de Buenos Aires, Instituto de Investigaci\u00f3n en Fisiopatolog\u00eda y Bioqu\u00edmica Cl\u00ednica (INFIBIOC), Buenos Aires C1113AAD, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea Carolina","family":"Entrocassi","sequence":"additional","affiliation":[{"name":"Universidad de Buenos Aires, Facultad de Farmacia y Bioqu\u00edmica, Microbiolog\u00eda Cl\u00ednica, Buenos Aires C1113AAD, Argentina"},{"name":"Universidad de Buenos Aires, Instituto de Investigaci\u00f3n en Fisiopatolog\u00eda y Bioqu\u00edmica Cl\u00ednica (INFIBIOC), Buenos Aires C1113AAD, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Luc\u00eda","family":"Gallo Vaulet","sequence":"additional","affiliation":[{"name":"Universidad de Buenos Aires, Facultad de Farmacia y Bioqu\u00edmica, Microbiolog\u00eda Cl\u00ednica, Buenos Aires C1113AAD, Argentina"},{"name":"Universidad de Buenos Aires, Instituto de Investigaci\u00f3n en Fisiopatolog\u00eda y Bioqu\u00edmica Cl\u00ednica (INFIBIOC), Buenos Aires C1113AAD, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deysi","family":"L\u00f3pez Aquino","sequence":"additional","affiliation":[{"name":"Divisi\u00f3n Cirug\u00eda, Hospital Fern\u00e1ndez, Buenos Aires C1425AGP, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dolores","family":"Caffarena","sequence":"additional","affiliation":[{"name":"Centro Privado de Cirug\u00eda y Coloproctolog\u00eda, Buenos Aires C1060ABB, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7659-7956","authenticated-orcid":false,"given":"Luciana","family":"La Rosa","sequence":"additional","affiliation":[{"name":"Centro Privado de Cirug\u00eda y Coloproctolog\u00eda, Buenos Aires C1060ABB, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5898-6667","authenticated-orcid":false,"given":"Laura","family":"Svidler L\u00f3pez","sequence":"additional","affiliation":[{"name":"Divisi\u00f3n Cirug\u00eda, Hospital Fern\u00e1ndez, Buenos Aires C1425AGP, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osvaldo","family":"Degregorio","sequence":"additional","affiliation":[{"name":"Universidad de Buenos Aires, Ciencias Veterinarias, Salud P\u00fablica, Buenos Aires C1427CWO, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8729-2306","authenticated-orcid":false,"given":"Bj\u00f6rn","family":"Herrmann","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology, Uppsala University Hospital, 751 85 Uppsala, Sweden"},{"name":"Section of Clinical Microbiology, Department of Medical Sciences, Uppsala University, 751 85 Uppsala, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2543-4262","authenticated-orcid":false,"given":"Marcelo","family":"Rodr\u00edguez Fermepin","sequence":"additional","affiliation":[{"name":"Universidad de Buenos Aires, Facultad de Farmacia y Bioqu\u00edmica, Microbiolog\u00eda Cl\u00ednica, Buenos Aires C1113AAD, Argentina"},{"name":"Universidad de Buenos Aires, Instituto de Investigaci\u00f3n en Fisiopatolog\u00eda y Bioqu\u00edmica Cl\u00ednica (INFIBIOC), Buenos Aires C1113AAD, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,3,15]]},"reference":[{"key":"ref_1","unstructured":"World Health Organization (2021). 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