{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:19:25Z","timestamp":1760145565437,"version":"build-2065373602"},"reference-count":47,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T00:00:00Z","timestamp":1722297600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microorganisms"],"abstract":"<jats:p>Pregnant women (PW) are at a higher risk of diseases and hospitalization from viral respiratory infections, particularly influenza and SARS-CoV-2, due to cardiopulmonary and immunological changes. This study assessed the impact of viral respiratory infections on PW hospitalized with severe acute respiratory infection (SARI) prior to the COVID-19 pandemic. It is a cross-sectional study with 42 PW and 85 non-pregnant women (NPW) admitted with SARI to two tertiary hospitals between January 2015 and December 2019. The rates of virus prevalence, SARI hospitalization, length of hospital stay, oxygen supplementation, intensive care unit (ICU) admission, and death were comparable between PW and NPW. A multivariate analysis showed that PW had a higher rate of viral SARI hospitalizations (OR = 2.37; 95% CI = 1.02\u20135.48) as compared to NPW, with the influenza virus being the most prevalent (aOR = 7.58; 95% CI = 1.53\u201337.66). The length of hospital stays (aOR = 0.83; 95% CI = 0.73\u20130.95) and admissions to the ICU (aOR = 0.028; 95% CI = 0.004\u20130.25) were lower in PW as compared to hospitalized NPW. The influenza virus had a greater impact on the frequency of SARI in the group of PW, and these had a better outcome than NPW due to the earlier antiviral treatment they received.<\/jats:p>","DOI":"10.3390\/microorganisms12081555","type":"journal-article","created":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T08:51:42Z","timestamp":1722329502000},"page":"1555","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A Retrospective Cross-Sectional Analysis of Viral SARI in Pregnant Women in Southern Brazil"],"prefix":"10.3390","volume":"12","author":[{"given":"Sonia Maria","family":"Lissa","sequence":"first","affiliation":[{"name":"Postgraduate Program in Tocogynecology and Women\u2019s Health, Federal University of Parana Universidade Federal do Paran\u00e1, Curitiba 80060-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6136-4527","authenticated-orcid":false,"given":"Bruna Amaral","family":"Lapinski","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Internal Medicine and Health Science, Federal University of Parana, Curitiba 80060-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Ester","family":"Graf","sequence":"additional","affiliation":[{"name":"Epidemiology Division, Hospital do Trabalhador, Curitiba 81050-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Somaia","family":"Reda","sequence":"additional","affiliation":[{"name":"Gynecology and Obstetrics Division, Hospital do Trabalhador, Curitiba 81050-000, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5888-859X","authenticated-orcid":false,"given":"Maria do Carmo","family":"Debur","sequence":"additional","affiliation":[{"name":"Public Health Laboratory, S\u00e3o Jos\u00e9 dos Pinhais 83060-500, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayra","family":"Presibella","sequence":"additional","affiliation":[{"name":"Public Health Laboratory, S\u00e3o Jos\u00e9 dos Pinhais 83060-500, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2638-3367","authenticated-orcid":false,"given":"Luciane Aparecida","family":"Pereira","sequence":"additional","affiliation":[{"name":"Virology Laboratory, Hospital de Cl\u00ednicas, Federal University of Parana, Curitiba 80060-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7561-4566","authenticated-orcid":false,"given":"Newton S\u00e9rgio","family":"de Carvalho","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Tocogynecology and Women\u2019s Health, Federal University of Parana Universidade Federal do Paran\u00e1, Curitiba 80060-900, Brazil"},{"name":"Department of Tocogynecology, Federal University of Parana, Curitiba 80060-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaqueline","family":"Carvalho de Oliveira","sequence":"additional","affiliation":[{"name":"Department of Genetics, Federal University of Parana, Curitiba 80060-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7907-7585","authenticated-orcid":false,"given":"Sonia Mara","family":"Raboni","sequence":"additional","affiliation":[{"name":"Infectious Diseases Division, Hospital de Cl\u00ednicas, Federal University of Parana, Curitiba 80060-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6221-2891","authenticated-orcid":false,"given":"Meri Bordignon","family":"Nogueira","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Tocogynecology and Women\u2019s Health, Federal University of Parana Universidade Federal do Paran\u00e1, Curitiba 80060-900, Brazil"},{"name":"Virology Laboratory, Hospital de Cl\u00ednicas, Federal University of Parana, Curitiba 80060-900, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,7,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.jcv.2017.07.019","article-title":"Systematic review of respiratory viral pathogens identified in adults with community-acquired pneumonia in Europe","volume":"95","author":"Alimi","year":"2017","journal-title":"J. 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