{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:36:44Z","timestamp":1792805804568,"version":"4.5.0"},"reference-count":49,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2024,11,15]],"date-time":"2024-11-15T00:00:00Z","timestamp":1731628800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"\u201cFondo Semilla\u201d from Universidad Aut\u00f3noma de Guadalajara","id":[{"id":"https:\/\/ror.org\/05ppk0267","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microorganisms"],"abstract":"<jats:p>Community-acquired urinary tract infections account for 15% of all outpatient use of antibiotics, and women are primarily affected; the major causative microorganism is uropathogenic Escherichia coli (E. coli). Treatment is indicated for cystitis and pyelonephritis and includes B-lactams (amoxicillin-clavulanic acid or third-generation cephalosporins), fluoroquinolones (ciprofloxacin or levofloxacin), nitrofurantoin, fosfomycin, and trimethoprim\u2013sulfamethoxazole. Resistance to antibiotic treatment is of concern; several mechanisms have been associated with the acquisition of genes that confer antimicrobial resistance to fluoroquinolones, which are often associated with other patterns of resistance, especially in extended-spectrum beta-lactamase (ESBL) producers. Several studies have addressed the prevalence of uropathogens producing ESBLs, but only a few have focused on fluoroquinolone resistance, and, to our knowledge, none have addressed the prevalence of phylotypes or genes responsible for antimicrobial resistance to fluoroquinolones. The focus of the present review was to analyze recently published papers that described the E. coli phylotype causing community-acquired UTIs in association with fluoroquinolone resistance.<\/jats:p>","DOI":"10.3390\/microorganisms12112320","type":"journal-article","created":{"date-parts":[[2024,11,15]],"date-time":"2024-11-15T04:47:17Z","timestamp":1731646037000},"page":"2320","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Fluoroquinolone Resistance in Escherichia coli Causing Community-Acquired Urinary Tract Infections: A Systematic Review"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-7848-4455","authenticated-orcid":false,"given":"Ana P.","family":"Ruiz-Lievano","sequence":"first","affiliation":[{"name":"Facultad de Medicina Humana, Universidad Aut\u00f3noma de Chiapas, Tuxtla Guti\u00e9rrez 29050, Chiapas, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Cervantes-Flores","sequence":"additional","affiliation":[{"name":"Facultad de Medicina, Benem\u00e9rita Universidad Aut\u00f3noma de Puebla, Puebla 72410, Puebla, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Nava-Torres","sequence":"additional","affiliation":[{"name":"Unidad Acad\u00e9mica Ciencias de la Salud, Universidad Aut\u00f3noma de Guadalajara, Zapopan 45129, Jalisco, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo J.","family":"Carbajal-Morales","sequence":"additional","affiliation":[{"name":"Unidad Acad\u00e9mica Ciencias de la Salud, Universidad Aut\u00f3noma de Guadalajara, Zapopan 45129, Jalisco, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luisa F.","family":"Villase\u00f1or-Garcia","sequence":"additional","affiliation":[{"name":"Unidad Acad\u00e9mica Ciencias de la Salud, Universidad Aut\u00f3noma de Guadalajara, Zapopan 45129, Jalisco, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6508-9657","authenticated-orcid":false,"given":"Maria G.","family":"Zavala-Cerna","sequence":"additional","affiliation":[{"name":"Unidad Acad\u00e9mica Ciencias de la Salud, Universidad Aut\u00f3noma de Guadalajara, Zapopan 45129, Jalisco, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,11,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.idc.2013.10.003","article-title":"Diagnosis and management of urinary tract infection in the emergency department and outpatient settings","volume":"28","author":"Takhar","year":"2014","journal-title":"Infect. 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