{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T13:52:32Z","timestamp":1775137952124,"version":"3.50.1"},"reference-count":31,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2024,12,13]],"date-time":"2024-12-13T00:00:00Z","timestamp":1734048000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microorganisms"],"abstract":"<jats:p>Monkeypox (Mpox) is an infectious disease caused by the Mpox virus belonging to the Orthopoxvirus genus in the Poxviridae family and has been declared by the WHO as a global health emergency owing to its rapid spread during 2022 and 2023. All patients diagnosed with Mpox who were confirmed by PCR between July 2022 and April 2023 were included in this study. In total, 405 patients in whom clade 2 was identified were included. Notably, 99% of included patients were men, with 82% of them aged 20\u201339 years. Furthermore, 71% were men who had sex with men, and 34% were HIV carriers. Regarding the morphology of the lesions, approximately 63% presented with papulonecrotic rash, which sometimes alternated with pustules depending on the stage they were in. All patients presented with systemic symptoms. Five patients required hospital admission, one of whom died, and presented with HIV and severe immunosuppression. Clinical findings suggest that contact during sexual intercourse is the most likely transmission mechanism and genital involvement is the most frequent clinical form. HIV was the primary comorbidity. Genital lesions were common, especially in vulnerable populations such as those who engage in high-risk sexual behaviors.<\/jats:p>","DOI":"10.3390\/microorganisms12122576","type":"journal-article","created":{"date-parts":[[2024,12,13]],"date-time":"2024-12-13T03:51:08Z","timestamp":1734061868000},"page":"2576","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Understanding the Epidemiology of Monkeypox Virus to Prevent Future Outbreaks"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7937-4459","authenticated-orcid":false,"given":"Jimmy Steven","family":"Vel\u00e1squez","sequence":"first","affiliation":[{"name":"Dermatology Department, Hospital Regional de Occidente San Juan de Dios, Quetzaltenango 09001, Guatemala"},{"name":"Fundaci\u00f3n Vithas, Grupo Hospitalario Vithas, 28043 Madrid, Spain"},{"name":"Ibero-Latin American College of Dermatology (CILAD), Buenos Aires C1091, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabiola Beatriz","family":"Herrera-Echeverr\u00eda","sequence":"additional","affiliation":[{"name":"Dermatology Department, Hospital General San Juan de Dios, Guatemala 01001, Guatemala"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00e9ctor Salvador","family":"Porres-Paredes","sequence":"additional","affiliation":[{"name":"Dermatology Department, Hospital Regional de Occidente San Juan de Dios, Quetzaltenango 09001, Guatemala"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9939-0771","authenticated-orcid":false,"given":"Carmen","family":"Rodr\u00edguez-Cerdeira","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3n Vithas, Grupo Hospitalario Vithas, 28043 Madrid, Spain"},{"name":"Ibero-Latin American College of Dermatology (CILAD), Buenos Aires C1091, Argentina"},{"name":"Dermatology Department, Grupo Hospitalario (CMQ Concheiro), Manuel Olivi\u00e9 11, 36203 Vigo, Spain"},{"name":"Department of Health Sciences, University of Vigo, Campus of Vigo, As Lagoas, 36310 Vigo, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,12,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/5584_2022_740","article-title":"Monkeypox and sexually transmitted diseases","volume":"1410","author":"Mungmunpuntipantip","year":"2022","journal-title":"Adv. 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