{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:54:55Z","timestamp":1790744095689,"version":"4.1.0"},"reference-count":68,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microorganisms"],"abstract":"<jats:p>Recent interest in the diverse ecosystem of bacteria, fungi, parasites, and viruses that make up the skin microbiome has led to several studies investigating the microbiome in healthy skin and in a variety of dermatological conditions. An imbalance of the normal skin flora can cause some skin diseases, and current culture techniques are often unable to detect a microorganism to further our understanding of the clinical\u2013microbiological correlates of disease and dysbiosis. Atopic dermatitis and rosacea are presentations that GPs often manage that may have an infective or microbiological component and can be challenging to treat. We aim to discuss the implications of the skin microbiome including the impact of dysbiosis on conditions such as these. We will also discuss some clinical pearls for initial and future directions of the management of conditions such as atopic dermatitis, rosacea, and hidradenitis suppurativa. Further research using culture-independent techniques is needed for conditions involving microbial dysbiosis to advance our knowledge of skin disease pathophysiology and guide future management.<\/jats:p>","DOI":"10.3390\/microorganisms13010054","type":"journal-article","created":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T11:24:19Z","timestamp":1735730659000},"page":"54","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["An Overview of the Skin Microbiome, the Potential for Pathogen Shift, and Dysbiosis in Common Skin Pathologies"],"prefix":"10.3390","volume":"13","author":[{"given":"Anita","family":"Smith","sequence":"first","affiliation":[{"name":"Healthy Skin Team, Wesfarmers Centre of Vaccines and Infectious Diseases, The Kids Research Institute Australia, Perth, WA 6009, Australia"},{"name":"Perth Children\u2019s Hospital, Perth, WA 6009, Australia"},{"name":"School of Medicine, University of Notre Dame, Fremantle, WA 6160, Australia"},{"name":"Sir Charles Gairdner Hospital, Perth, WA 6009, Australia"},{"name":"Department of Dermatology, Fiona Stanley Hospital, Perth, WA 6150, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta","family":"Dumbrava","sequence":"additional","affiliation":[{"name":"Sir Charles Gairdner Hospital, Perth, WA 6009, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noor-Ul-Huda","family":"Ghori","sequence":"additional","affiliation":[{"name":"Healthy Skin Team, Wesfarmers Centre of Vaccines and Infectious Diseases, The Kids Research Institute Australia, Perth, WA 6009, Australia"},{"name":"Division of Infection and Immunity, School of Biomedical Sciences, University of Western Australia, Perth, WA 6009, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachael","family":"Foster","sequence":"additional","affiliation":[{"name":"Healthy Skin Team, Wesfarmers Centre of Vaccines and Infectious Diseases, The Kids Research Institute Australia, Perth, WA 6009, Australia"},{"name":"Perth Children\u2019s Hospital, Perth, WA 6009, Australia"},{"name":"Sir Charles Gairdner Hospital, Perth, WA 6009, Australia"},{"name":"Department of Dermatology, Fiona Stanley Hospital, Perth, WA 6150, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Campbell","sequence":"additional","affiliation":[{"name":"Central Perth Skin Clinic, Perth, WA 6000, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Duthie","sequence":"additional","affiliation":[{"name":"Central Perth Skin Clinic, Perth, WA 6000, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7370-9139","authenticated-orcid":false,"given":"Gerard","family":"Hoyne","sequence":"additional","affiliation":[{"name":"Institute of Respiratory Health, QEII Medical Centre, Perth, WA 6009, Australia"},{"name":"School of Health Sciences, University of Notre Dame, Fremantle, WA 6160, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3393-6748","authenticated-orcid":false,"given":"Marius","family":"Rademaker","sequence":"additional","affiliation":[{"name":"Clinical Trials New Zealand, Hamilton 3204, New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asha C.","family":"Bowen","sequence":"additional","affiliation":[{"name":"Healthy Skin Team, Wesfarmers Centre of Vaccines and Infectious Diseases, The Kids Research Institute Australia, Perth, WA 6009, Australia"},{"name":"Perth Children\u2019s Hospital, Perth, WA 6009, Australia"},{"name":"School of Medicine, University of Notre Dame, Fremantle, WA 6160, Australia"},{"name":"Division of Paediatrics, School of Medicine, University of Western Australia, Perth, WA 6009, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,1,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Chen, Y., Knight, R., and Gallo, R.L. 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