{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:07:10Z","timestamp":1760058430427,"version":"build-2065373602"},"reference-count":48,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T00:00:00Z","timestamp":1744243200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","award":["2017\/12271-0"],"award-info":[{"award-number":["2017\/12271-0"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microorganisms"],"abstract":"<jats:p>Brazilian family farming comprises production units that represent approximately 86.40% of agricultural establishments, playing a significant national role in socio-environmental and economic sectors. The state of S\u00e3o Paulo is known for its rural and urban development, including agricultural settlements such as Pontal do Paranapanema. This sector requires attention due to the emergence of infectious diseases, such as leptospirosis, a widespread zoonotic disease that causes losses in agricultural productivity. This study aimed to analyze the prevalence of leptospirosis in dairy cattle within the settlements of Presidente Epit\u00e1cio and Mirante do Paranapanema. All animals underwent serological testing. The overall prevalence of Leptospira spp. was 58.93%. Additionally, the prevalence of antibodies against Leptospira spp. was 59.20% in multiparous cows and 58.60% in primiparous cows. A correlation was also observed between animals with retained placenta and seropositive animals for Leptospira spp. antibodies. Based on this study, we highlight that the high prevalence of leptospirosis underscores the presence of this pathology in settlements within the Pontal do Paranapanema region. Consequently, there is a need to develop public policy programs, alongside sanitary and control measures, to mitigate the impact on dairy farming in the region.<\/jats:p>","DOI":"10.3390\/microorganisms13040865","type":"journal-article","created":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T11:26:41Z","timestamp":1744284401000},"page":"865","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical and Epidemiological Study of Leptospirosis in the Settlements of Presidente Epitacio and Mirante do Paranapanema"],"prefix":"10.3390","volume":"13","author":[{"given":"Mario A. R.","family":"Aleman","sequence":"first","affiliation":[{"name":"University of Valle de Puebla, Puebla 72440, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6397-605X","authenticated-orcid":false,"given":"Natalia C.","family":"Gaeta","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine and Animal Science, University of S\u00e3o Paulo, S\u00e3o Paulo 05508-220, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9225-0573","authenticated-orcid":false,"given":"Vanessa","family":"Castro","sequence":"additional","affiliation":[{"name":"Biological Institute of the State of S\u00e3o Paulo, S\u00e3o Paulo 04016-035, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo C.","family":"Marques","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine and Animal Science, University of S\u00e3o Paulo, S\u00e3o Paulo 05508-220, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4303-0504","authenticated-orcid":false,"given":"Bruno L. M.","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, School of Veterinary Medicine, Federal University of Mato Grosso, Sinop 78550-728, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-7093-0951","authenticated-orcid":false,"given":"Zenaide S.","family":"Ol\u00edmpio","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine and Animal Science, University of S\u00e3o Paulo, S\u00e3o Paulo 05508-220, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0240-3025","authenticated-orcid":false,"given":"Lilian","family":"Gregory","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine and Animal Science, University of S\u00e3o Paulo, S\u00e3o Paulo 05508-220, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,4,10]]},"reference":[{"key":"ref_1","unstructured":"IBGE\u2013Instituto Brasileiro de Geografia e Estat\u00edstica (2024, October 21). \u00c1rea Destinada \u00e0 Colheita, Quantidade Produzida e Valor da Produ\u00e7\u00e3o da Lavoura Permanente, Available online: https:\/\/www.ibge.gov.br\/estatisticas\/economicas\/agricultura-e-pecuaria\/9117-producao-agricola-municipal-culturas-temporarias-e-permanentes.html."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"e43411226098","DOI":"10.33448\/rsd-v11i2.26098","article-title":"Uma Revis\u00e3o Sistem\u00e1tica Sobre a Contribui\u00e7\u00e3o Das Cooperativas Para a Sustentabilidade Da Agricultura Familiar","volume":"11","author":"Bertolini","year":"2022","journal-title":"Res. 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