{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T14:51:56Z","timestamp":1770821516859,"version":"3.50.1"},"reference-count":115,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T00:00:00Z","timestamp":1745884800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"the Colegio de Postgraduados, Campus San Luis Potos\u00ed. The first author received scholarship from the Secretariat of Science, Humanities, Technology and Innovation (SECIHTI)","award":["1261494"],"award-info":[{"award-number":["1261494"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microorganisms"],"abstract":"<jats:p>Jatropha dioica Sess\u00e9 (JD) is a plant from arid and semiarid zones of Mexico related to local therapeutic uses and possible use in food and agriculture as a control agent of pest organisms that helps to reduce impacts on the environment, human health and resistance by phytopathogens. In vitro bactericidal activity was evaluated with the well diffusion method in doses of 1000, 2500, 5000, 7500, 10,000 and 20,000 \u00b5g mL\u22121, and fungistatic activity was evaluated with the agar dilution method (500, 1000, 1500, 2000 and 4000 \u00b5g mL\u22121) in Pseudomonas syringae, Botrytis cinerea and Fusarium oxysporum using hydroalcoholic extracts of J. dioica root in a completely randomized design with five replications. Total phenol and flavonoid contents were recorded by the Folin\u2013Ciocalteu and aluminum chloride methods. Ethanol and methanol extracts showed fungistatic activity on B. cinerea, inhibiting from 42.27 \u00b1 1.09 to 46.68 \u00b1 0.98 mg mL\u22121, with an IC50 of 5.04 mg mL\u22121, with no differences by solvent type. In F. oxysporum, inhibition ranged from 14.77 \u00b1 1.08 to 29.19 \u00b1 0.89 mg mL\u22121, and the methanol extract was more efficient, generating a stress response to the ethanol extract. The bactericidal activity on P. syringae recorded inhibition zones of 17.66 \u00b1 0.33 and 16.66 \u00b1 0.33 mg mL\u22121, with ethanol being more efficient. The phenol content ranged from 8.92 \u00b1 0.25 to 12.10 \u00b1 0.34 mg EAG g\u22121 and flavonoid content ranged from 20.49 \u00b1 0.33 to 28.21 \u00b1 0.73 mg QE g\u22121 of sample dry weight. The results highlight the biological activity of J. dioica as an alternative to biopesticides that minimize agrochemical applications and generate pathogen resistance. These advances contribute to the revaluation and conservation of the species.<\/jats:p>","DOI":"10.3390\/microorganisms13051027","type":"journal-article","created":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T07:49:36Z","timestamp":1745912976000},"page":"1027","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Fungistatic and Bactericidal Activity of Hydroalcoholic Extracts of Root of Jatropha dioica Sess\u00e9"],"prefix":"10.3390","volume":"13","author":[{"given":"Lizeth","family":"Aguilar-Galaviz","sequence":"first","affiliation":[{"name":"Colegio de Postgraduados, Innovaci\u00f3n en Manejo de Recursos Naturales, Campus San Luis Potos\u00ed, Iturbide 73, Salinas de Hidalgo 78600, SLP, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6427-0646","authenticated-orcid":false,"given":"Jorge","family":"Cadena-I\u00f1iguez","sequence":"additional","affiliation":[{"name":"Colegio de Postgraduados, Innovaci\u00f3n en Manejo de Recursos Naturales, Campus San Luis Potos\u00ed, Iturbide 73, Salinas de Hidalgo 78600, SLP, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4360-1685","authenticated-orcid":false,"given":"Dalia Abigail","family":"Garc\u00eda-Flores","sequence":"additional","affiliation":[{"name":"Colegio de Postgraduados, Innovaci\u00f3n en Manejo de Recursos Naturales, Campus San Luis Potos\u00ed, Iturbide 73, Salinas de Hidalgo 78600, SLP, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5339-3819","authenticated-orcid":false,"given":"Gerardo","family":"Loera-Alvarado","sequence":"additional","affiliation":[{"name":"Colegio de Postgraduados, Innovaci\u00f3n en Manejo de Recursos Naturales, Campus San Luis Potos\u00ed, Iturbide 73, Salinas de Hidalgo 78600, SLP, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego","family":"Rivera-Escare\u00f1o","sequence":"additional","affiliation":[{"name":"Colegio de Postgraduados, Innovaci\u00f3n en Manejo de Recursos Naturales, Campus San Luis Potos\u00ed, Iturbide 73, Salinas de Hidalgo 78600, SLP, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Azucena","family":"Ortega-Amaro","sequence":"additional","affiliation":[{"name":"Coordinaci\u00f3n Acad\u00e9mica Regi\u00f3n Altiplano Oeste, Universidad Aut\u00f3noma de San Luis Potos\u00ed, Carretera Salinas-Santo Domingo 200, Salinas de Hidalgo 78600, SLP, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,4,29]]},"reference":[{"key":"ref_1","first-page":"267","article-title":"Mapeo del \u00edndice de aridez y su distribuci\u00f3n poblacional en M\u00e9xico","volume":"17","year":"2011","journal-title":"Rev. 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