{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:01:29Z","timestamp":1787313689201,"version":"build-2736575974"},"reference-count":40,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T00:00:00Z","timestamp":1745971200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microorganisms"],"abstract":"<jats:p>Urinary actinomycosis is a rare condition, often mimicking a urinary tract tumor. Due to its low prevalence, it can be challenging to diagnose and may be mistaken for malignancies. A 33-year-old female patient with a history of type 2 Diabetes Mellitus and recurrent urinary tract infections presented to the emergency room with right renal fossa pain radiating to the right hypochondrium, fever with chills, nausea, and vomiting. Physical examination revealed a positive Giordano sign and tenderness at the ipsilateral middle and upper ureteral points. A contrast-enhanced CT scan showed a mass infiltrating the distal third of the right ureter, causing retrograde dilatation and hydronephrosis. Additionally, a liver injury with both liquid and solid components was observed. Therefore, given the suspicion of a urothelial tumor, a diagnostic cystoscopy and ureteroscopy were performed. Using interventional radiology, an abscessed liver lesion was drained, yielding purulent fluid. The histopathological examination revealed no evidence of malignancy. However, due to the strong suspicion of upper urinary tract urothelial carcinoma, a right radical nephroureterectomy with bladder cuff excision and retroperitoneal lymphadenectomy was performed. Histopathological examination ultimately confirmed urinary actinomycosis. Consequently, antibiotic therapy with oral amoxicillin 2 g every 12 h was initiated, leading to a good clinical response. Despite its low incidence, urinary actinomycosis should be considered as a differential diagnosis in cases suspected of urothelial tumors in the upper urinary tract. Increased awareness of this rare condition may help prevent unnecessary surgical interventions.<\/jats:p>","DOI":"10.3390\/microorganisms13051033","type":"journal-article","created":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T05:05:57Z","timestamp":1745989557000},"page":"1033","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Uncommon Urinary Actinomycosis Mimicking Upper Urinary Tract Urothelial Tumor: Case Report and Literature Review"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3931-3114","authenticated-orcid":false,"given":"Patricia A.","family":"Meza-Meneses","sequence":"first","affiliation":[{"name":"Infectology Service, Hospital Regional de Alta Especialidad de Ixtapaluca, Servicios de Salud del Instituto Mexicano de Seguro Social Para el Bienestar (IMSS-BIENESTAR), Carretera Federal Mexico-Puebla Km 34.5, Ixtapaluca 56530, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-4118-386X","authenticated-orcid":false,"given":"Rodrigo P\u00e9rez","family":"Becerra","sequence":"additional","affiliation":[{"name":"Urology Service, Hospital Regional de Alta Especialidad de Ixtapaluca, Servicios de Salud del Instituto Mexicano de Seguro Social Para el Bienestar (IMSS-BIENESTAR), Carretera Federal Mexico-Puebla Km 34.5, Ixtapaluca 56530, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerardo Garza","family":"Sainz","sequence":"additional","affiliation":[{"name":"Urology Service, Hospital Regional de Alta Especialidad de Ixtapaluca, Servicios de Salud del Instituto Mexicano de Seguro Social Para el Bienestar (IMSS-BIENESTAR), Carretera Federal Mexico-Puebla Km 34.5, Ixtapaluca 56530, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis Trujillo","family":"Ortiz","sequence":"additional","affiliation":[{"name":"Urology Service, Hospital Regional de Alta Especialidad de Ixtapaluca, Servicios de Salud del Instituto Mexicano de Seguro Social Para el Bienestar (IMSS-BIENESTAR), Carretera Federal Mexico-Puebla Km 34.5, Ixtapaluca 56530, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4287-0077","authenticated-orcid":false,"given":"Adri\u00e1n Martinez","family":"Correa","sequence":"additional","affiliation":[{"name":"Urology Service, Hospital Regional de Alta Especialidad de Ixtapaluca, Servicios de Salud del Instituto Mexicano de Seguro Social Para el Bienestar (IMSS-BIENESTAR), Carretera Federal Mexico-Puebla Km 34.5, Ixtapaluca 56530, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan Rodrigo P\u00e9rez","family":"Soriano","sequence":"additional","affiliation":[{"name":"Urology Service, Hospital Regional de Alta Especialidad de Ixtapaluca, Servicios de Salud del Instituto Mexicano de Seguro Social Para el Bienestar (IMSS-BIENESTAR), Carretera Federal Mexico-Puebla Km 34.5, Ixtapaluca 56530, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruben Miguel Angel","family":"Santiago Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Urology Service, Hospital Regional de Alta Especialidad de Ixtapaluca, Servicios de Salud del Instituto Mexicano de Seguro Social Para el Bienestar (IMSS-BIENESTAR), Carretera Federal Mexico-Puebla Km 34.5, Ixtapaluca 56530, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aar\u00f3n Delgado","family":"Corral","sequence":"additional","affiliation":[{"name":"Urology Service, Hospital Regional de Alta Especialidad de Ixtapaluca, Servicios de Salud del Instituto Mexicano de Seguro Social Para el Bienestar (IMSS-BIENESTAR), Carretera Federal Mexico-Puebla Km 34.5, Ixtapaluca 56530, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar Vieyra","family":"Valdez","sequence":"additional","affiliation":[{"name":"Urology Service, Hospital Regional de Alta Especialidad de Ixtapaluca, Servicios de Salud del Instituto Mexicano de Seguro Social Para el Bienestar (IMSS-BIENESTAR), Carretera Federal Mexico-Puebla Km 34.5, Ixtapaluca 56530, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Genaro Arg\u00fcelles","family":"Morales","sequence":"additional","affiliation":[{"name":"Urology Service, Hospital Regional de Alta Especialidad de Ixtapaluca, Servicios de Salud del Instituto Mexicano de Seguro Social Para el Bienestar (IMSS-BIENESTAR), Carretera Federal Mexico-Puebla Km 34.5, Ixtapaluca 56530, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario Alberto Toledo","family":"D\u00edaz","sequence":"additional","affiliation":[{"name":"Urology Service, Hospital Regional de Alta Especialidad de Ixtapaluca, Servicios de Salud del Instituto Mexicano de Seguro Social Para el Bienestar (IMSS-BIENESTAR), Carretera Federal Mexico-Puebla Km 34.5, Ixtapaluca 56530, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto Saldivar","family":"Luna","sequence":"additional","affiliation":[{"name":"Urology Service, Hospital Regional de Alta Especialidad de Ixtapaluca, Servicios de Salud del Instituto Mexicano de Seguro Social Para el Bienestar (IMSS-BIENESTAR), Carretera Federal Mexico-Puebla Km 34.5, Ixtapaluca 56530, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1277-7170","authenticated-orcid":false,"given":"Carlos Alberto","family":"Castro-Fuentes","sequence":"additional","affiliation":[{"name":"Research Unit, Hospital Regional de Alta Especialidad de Ixtapaluca, Servicios de Salud del Instituto Mexicano de Seguro Social Para el Bienestar (IMSS-BIENESTAR), Carretera Federal Mexico-Puebla Km 34.5, Ixtapaluca 56530, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-1302-1939","authenticated-orcid":false,"given":"Victor","family":"Osornio S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Urology Service, Hospital Regional de Alta Especialidad de Ixtapaluca, Servicios de Salud del Instituto Mexicano de Seguro Social Para el Bienestar (IMSS-BIENESTAR), Carretera Federal Mexico-Puebla Km 34.5, Ixtapaluca 56530, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,4,30]]},"reference":[{"key":"ref_1","first-page":"183","article-title":"Actinomycosis: Etiology, Clinical Features, Diagnosis, Treatment, and Management","volume":"7","author":"Valour","year":"2014","journal-title":"Infect. 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