{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T01:06:38Z","timestamp":1779325598412,"version":"3.51.4"},"reference-count":70,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T00:00:00Z","timestamp":1745971200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"VICTOR BABES UNIVERSITY OF MEDICINE AND PHARMACY TIMISOARA"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microorganisms"],"abstract":"<jats:p>Cystic echinococcosis (CE) is a serious health problem in many countries worldwide, including in Romania, because of the high infection rates in both humans and animals. We retrospectively assessed the demographic and epidemiological features of CE in children and adults hospitalized in Western Romania between 2007\u20132022. Analyzed data were collected from the hospitals\u2019 medical records. This research involved 426 subjects (3\u201390 years): 60 (14.1%) children and 366 (85.9%) adults. A decreasing trend in the number of cases was noted during the analyzed period (p = 0.004). Multiple-organ involvement was reported in 16.7% of the children and in 6.3% of the adults (p = 0.005). The liver was the most commonly affected organ. The rate of lung involvement was higher in children (25%) than in adults (13.1%) (p = 0.02). Most of the patients had one hospital presentation (74.9%). Multiple hospitalizations were reported in 40% of the children and 22.7% of the adults (p = 0.004). CE is a severe zoonotic disease that impacts individuals of all ages. Despite the decline in cases, CE remains a public-health problem in Western Romania. Health programs that target risk factors and control measures should be implemented to stop the parasite\u2019s spread and maintain the trend toward reduced numbers of CE cases.<\/jats:p>","DOI":"10.3390\/microorganisms13051035","type":"journal-article","created":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T05:05:57Z","timestamp":1745989557000},"page":"1035","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Cystic Echinococcosis in Hospitalized Children and Adults from Western Romania: 2007\u20132022"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6235-9076","authenticated-orcid":false,"given":"Ana Alexandra","family":"Ardelean","sequence":"first","affiliation":[{"name":"Discipline of Parasitology, Department of Infectious Diseases, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania"},{"name":"Center for Diagnosis and Study of Parasitic Diseases, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania"},{"name":"Patogen Preventia, 300124 Timisoara, Romania"},{"name":"Clinical Laboratory, Municipal Clinical Emergency Hospital, 300254 Timisoara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Alina","family":"Lupu","sequence":"additional","affiliation":[{"name":"Discipline of Parasitology, Department of Infectious Diseases, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania"},{"name":"Center for Diagnosis and Study of Parasitic Diseases, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania"},{"name":"Patogen Preventia, 300124 Timisoara, Romania"},{"name":"Clinical Laboratory, Institute of Cardiovascular Diseases, 300310 Timisoara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2854-7449","authenticated-orcid":false,"given":"Laurentiu Vasile","family":"Sima","sequence":"additional","affiliation":[{"name":"Discipline of Surgical Semiology I, Department IX-Surgery I, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania"},{"name":"General Surgery Clinic, Municipal Clinical Emergency Hospital, 300254 Timisoara, Romania"},{"name":"Center for Hepato-Biliary-Pancreatic Surgery (CHBP), Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriel Veniamin","family":"Cozma","sequence":"additional","affiliation":[{"name":"Discipline of Surgical Semiology I and Thoracic Surgery, Department IX-Surgery I, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania"},{"name":"Thoracic Surgery Clinic, Municipal Clinical Emergency Hospital, 300254 Timisoara, Romania"},{"name":"Thoracic Surgery Research Center, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandru","family":"Nesiu","sequence":"additional","affiliation":[{"name":"Department of Biology and Life Science, Faculty of Medicine, Vasile Goldis Western University of Arad, 310025 Arad, Romania"},{"name":"\u201cAurel Ardelean\u201d Institute of Life Sciences, Vasile Goldis Western University of Arad, 310414 Arad, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5218-9026","authenticated-orcid":false,"given":"Alin Gabriel","family":"Mihu","sequence":"additional","affiliation":[{"name":"Center for Diagnosis and Study of Parasitic Diseases, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania"},{"name":"Patogen Preventia, 300124 Timisoara, Romania"},{"name":"Department of Biology and Life Science, Faculty of Medicine, Vasile Goldis Western University of Arad, 310025 Arad, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Octavian Marius","family":"Cretu","sequence":"additional","affiliation":[{"name":"Discipline of Surgical Semiology I, Department IX-Surgery I, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania"},{"name":"General Surgery Clinic, Municipal Clinical Emergency Hospital, 300254 Timisoara, Romania"},{"name":"Center for Hepato-Biliary-Pancreatic Surgery (CHBP), Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1094-3729","authenticated-orcid":false,"given":"Tudor Rares","family":"Olariu","sequence":"additional","affiliation":[{"name":"Discipline of Parasitology, Department of Infectious Diseases, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania"},{"name":"Center for Diagnosis and Study of Parasitic Diseases, Department of Infectious Disease, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania"},{"name":"Patogen Preventia, 300124 Timisoara, Romania"},{"name":"Clinical Laboratory, Municipal Clinical Emergency Hospital, 300254 Timisoara, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,4,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1089\/fpd.2024.0034","article-title":"Pediatric Cystic Echinococcosis in Tehran, Iran: A 9-Year Retrospective Epidemiological and Clinical Survey of Hospitalized Cases","volume":"21","author":"Mahmoudi","year":"2024","journal-title":"Foodborne Pathog. 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