{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T05:14:26Z","timestamp":1792214066099,"version":"4.4.0"},"reference-count":208,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T00:00:00Z","timestamp":1749513600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012190","name":"Ministry of Science and Higher Education of the Russian Federation","doi-asserted-by":"publisher","award":["124020500028-4"],"award-info":[{"award-number":["124020500028-4"]}],"id":[{"id":"10.13039\/501100012190","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microorganisms"],"abstract":"<jats:p>Researchers have identified mercury as one of the most toxic environmental pollutants, with deleterious effects on human health and biota. Microorganisms play a key role in the accumulation, degradation, and neutralisation of mercury. Numerous bacteria, fungi, and microalgae possess the mer operon and its homologues, which contain genes responsible for the transport and detoxification of mercury compounds. Mercury-tolerant Microorganisms efficiently convert mercury into less toxic forms. Their tolerance characteristics position them as promising agents for the remediation of ecosystems altered by human activity. This review explores the mechanisms by which microorganisms resist mercury and their potential for biotechnological applications, including eco-friendly and cost-effective bioremediation of mercury-contaminated environments.<\/jats:p>","DOI":"10.3390\/microorganisms13061350","type":"journal-article","created":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T12:53:16Z","timestamp":1749559996000},"page":"1350","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Diversity of Mercury-Tolerant Microorganisms"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4036-9817","authenticated-orcid":false,"given":"Anastasia A.","family":"Golysheva","sequence":"first","affiliation":[{"name":"Institute of Ecology and Genetics of Microorganisms, Perm Federal Research Center of the Ural Branch of the Russian Academy of Sciences, 13 Golev Str., Perm 614081, Russia"},{"name":"Department of Microbiology and Immunology, Perm State National Research University, 15 Bukirev Street, Perm 614068, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lyudmila V.","family":"Litvinenko","sequence":"additional","affiliation":[{"name":"Institute of Ecology and Genetics of Microorganisms, Perm Federal Research Center of the Ural Branch of the Russian Academy of Sciences, 13 Golev Str., Perm 614081, Russia"},{"name":"Department of Microbiology and Immunology, Perm State National Research University, 15 Bukirev Street, Perm 614068, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2558-4789","authenticated-orcid":false,"given":"Irina B.","family":"Ivshina","sequence":"additional","affiliation":[{"name":"Institute of Ecology and Genetics of Microorganisms, Perm Federal Research Center of the Ural Branch of the Russian Academy of Sciences, 13 Golev Str., Perm 614081, Russia"},{"name":"Department of Microbiology and Immunology, Perm State National Research University, 15 Bukirev Street, Perm 614068, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,6,10]]},"reference":[{"key":"ref_1","first-page":"133","article-title":"Heavy metals toxicity and the environment","volume":"101","author":"Tchounwou","year":"2012","journal-title":"Exp. Suppl."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/j.jhazmat.2009.07.118","article-title":"Remediation of soils contaminated with polycyclic aromatic hydrocarbons (PAHs)","volume":"172","author":"Gan","year":"2009","journal-title":"J. Hazard. Mater."},{"key":"ref_3","first-page":"12","article-title":"Methods of removing heavy metals from industrial wastewater","volume":"1","author":"Gunatilake","year":"2015","journal-title":"J. Multidiscip. Eng. Sci. Stud. (JMESS)"},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Morin-Crini, N., and Crini, G. (2017). Eaux Industrielles Contamin\u00e9es, Presses universitaires de Franche-Comt\u00e9. Chapitre I.","DOI":"10.4000\/books.pufc.10857"},{"key":"ref_5","first-page":"34","article-title":"Resistance to and accumulation of heavy metals by actinobacteria isolated from abandoned mining areas","volume":"1","author":"Baz","year":"2015","journal-title":"Sci. World J."},{"key":"ref_6","first-page":"100283","article-title":"Recent developments in environmental mercury bioremediation and its toxicity: A review","volume":"13","author":"Kumari","year":"2020","journal-title":"Environ. Nanotechnol. Monit. Manag."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"130654","DOI":"10.1016\/j.chemosphere.2021.130654","article-title":"Bioremediation: An effective approach of mercury removal from the aqueous solutions","volume":"280","author":"Rani","year":"2021","journal-title":"Chemosphere"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.chemosphere.2016.09.070","article-title":"Actinobacteria: Current research and perspectives for bioremediation of pesticides and heavy metals","volume":"166","author":"Alvarez","year":"2017","journal-title":"Chemosphere"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"8439","DOI":"10.1021\/es070908q","article-title":"Phytoremediation of mercury and organomercurials in chloroplast transgenic plants: Enhanced root uptake, translocation to shoots, and volatilization","volume":"41","author":"Hussein","year":"2007","journal-title":"Environ. Sci. Technol."},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Azevedo, B.F., Furieri, L.B., Pe\u00e7anha, F.M., Wiggers, G.A., Vassallo, P.F., Sim\u00f5es, M.R., Fiorim, J., de Batista, P.R., Fioresi, M., and Rossoni, L. (2012). Toxic effects of mercury on the cardiovascular and central nervous systems. J. Biomed. Biotechnol., 2012.","DOI":"10.1155\/2012\/949048"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.watres.2013.10.024","article-title":"Extremely elevated methyl mercury levels in water, sediment and organisms in a Romanian reservoir affected by release of mercury from a chloralkali plant","volume":"49","author":"Bravo","year":"2014","journal-title":"Water Res."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1007\/s13280-017-1004-9","article-title":"A review of global environmental mercury processes in response to human and natural perturbations: Changes of emissions, climate, and land use","volume":"47","author":"Obrist","year":"2018","journal-title":"Ambio."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1002\/jcb.26234","article-title":"Prevalence of exposure of heavy metals and their impact on health consequences","volume":"119","author":"Rehman","year":"2018","journal-title":"J. Cell. Biochem."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"e42696","DOI":"10.1016\/j.heliyon.2025.e42696","article-title":"Recent advances in the clinical management of intoxication by five heavy metals: Mercury, lead, chromium, cadmium and arsenic","volume":"11","author":"Etemad","year":"2025","journal-title":"Heliyon"},{"key":"ref_15","first-page":"11466","article-title":"Updated Global and Oceanic Mercury Budgets for the United Nations Global Mercury Assessment 2018","volume":"52","author":"Outridge","year":"2018","journal-title":"Environ. Sci. Technol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.etap.2005.03.007","article-title":"Low dose mercury toxicity and human health","volume":"20","author":"Zahir","year":"2005","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.marpolbul.2017.01.033","article-title":"Bioaccumulation and biomagnification of mercury and methylmercury in four sympatric coastal sharks in a protected subtropical lagoon","volume":"116","author":"Matulik","year":"2017","journal-title":"Mar. Pollut. Bull."},{"key":"ref_18","unstructured":"(1989). Basel Convention on the Control of Transboundary Movements of Hazardous Wastes and Their Disposal, United Nations Environment Programme. Available online: https:\/\/www.basel.int\/Portals\/4\/Basel%20Convention\/docs\/text\/BaselConventionText-r.pdf."},{"key":"ref_19","unstructured":"(2013). Minamata Convention on Mercury, United Nations Environment Programme. Available online: https:\/\/minamataconvention.org\/en\/resources\/minamata-convention-mercury-text-and-annexes."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"125022","DOI":"10.1016\/j.cej.2020.125022","article-title":"Development of selenized magnetite (Fe3O4\u2212xSey) as an efficient and recyclable trap for elemental mercury sequestration from coal combustion flue gas","volume":"394","author":"Yang","year":"2020","journal-title":"Chem. Eng. J."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1002\/gbc.20040","article-title":"Legacy impacts of all-time anthropogenic emissions on the global mercury cycle","volume":"27","author":"Amos","year":"2013","journal-title":"Glob. Biogeochem. Cycles"},{"key":"ref_22","unstructured":"AMAP\/UN Environment (2019). Technical Background Report to the Global Mercury Assessment 2018, Arctic Monitoring and Assessment Programme."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1021\/am200023w","article-title":"A universal sensor for mercury (Hg, Hg(I), Hg(II)) based on silver nanoparticle-embedded polymer thin film","volume":"3","author":"Ramesh","year":"2011","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"74","DOI":"10.3961\/jpmph.2014.47.2.74","article-title":"Environmental mercury and its toxic effects","volume":"47","author":"Rice","year":"2014","journal-title":"J. Prev. Med. Public Health"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.neuro.2012.04.005","article-title":"The relationship between the fish consumption and blood total\/methyl-mercury concentration of costal area in Korea","volume":"33","author":"You","year":"2012","journal-title":"Neurotoxicology"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1080\/15275922.2010.547549","article-title":"Mercury in natural waters: A mini-review","volume":"12","author":"Mousavi","year":"2011","journal-title":"Environ. Forensics"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.envint.2014.09.007","article-title":"Sources and remediation techniques for mercury contaminated soil","volume":"74","author":"Xu","year":"2015","journal-title":"Environ. Int."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/s11769-019-1026-2","article-title":"Measurement and scaling of mercury on soil and air in a historical artisanal gold mining area in northeastern China","volume":"29","author":"Wang","year":"2019","journal-title":"Chin. Geogr. Sci."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"126985","DOI":"10.1016\/j.jhazmat.2021.126985","article-title":"Cellular and genetic mechanism of bacterial mercury resistance and their role in biogeochemistry and bioremediation","volume":"423","author":"Priyadarshanee","year":"2022","journal-title":"J. Hazard. Mater."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1021\/es202793c","article-title":"Investigation of local mercury deposition from a coal-fired power plant using mercury isotopes","volume":"46","author":"Sherman","year":"2012","journal-title":"Environ. Sci. Technol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1186\/s12302-020-00401-x","article-title":"Mercury in the terrestrial environment: A review","volume":"32","author":"Gworek","year":"2020","journal-title":"Environ. Sci. Eur."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"105559","DOI":"10.1016\/j.resourpol.2025.105559","article-title":"Assessing the dual impact of gold mining on local communities: Socio-economic benefits and environmental challenges","volume":"103","author":"Haroon","year":"2025","journal-title":"Resour. Policy"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.envpol.2017.04.101","article-title":"Elemental mercury: Its unique properties affect its behavior and fate in the environment","volume":"229","author":"Liu","year":"2017","journal-title":"Environ. Pollut."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1146\/annurev.ecolsys.29.1.543","article-title":"The chemical cycle and bioaccumulation of mercury","volume":"29","author":"Morel","year":"1998","journal-title":"Annu. Rev. Ecol. Syst."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/s40726-022-00226-7","article-title":"The causes and effects of mercury and methylmercury contamination in the marine environment: A review","volume":"8","author":"Soubra","year":"2022","journal-title":"Curr. Pollut. Rep."},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"De, J., Dash, H.R., and Das, S. (2014). Mercury pollution and bioremediation\u2014A case study on biosorption by a mercury-resistant marine bacterium. Microb. Biodegrad. Bioremediation, 137\u2013166.","DOI":"10.1016\/B978-0-12-800021-2.00006-6"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"2664","DOI":"10.1021\/es034702a","article-title":"Effect of dissolved organic carbon on the photoproduction of dissolved gaseous mercury in lakes: Potential impacts of forestry","volume":"38","author":"Lean","year":"2004","journal-title":"Environ. Sci. Technol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.marchem.2007.04.002","article-title":"Factors influencing the oxidation, reduction, methylation and demethylation of mercury species in coastal waters","volume":"107","author":"Whalin","year":"2007","journal-title":"Mar. Chem."},{"key":"ref_39","doi-asserted-by":"crossref","unstructured":"Sharma, S.K., and Sanghi, R. (2012). Green practices to save our precious \u201cWater Resource\u201d. Advances in Water Treatment and Pollution Prevention, Springer.","DOI":"10.1007\/978-94-007-4204-8"},{"key":"ref_40","unstructured":"Mortula, M., and Ahmad, A. (2013). Leaching of antimony from bottle water. ACSEE, 85\u201388."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1134\/S0026261719020061","article-title":"Ability of the Dietzia, Gordonia and Rhodococcus actinobacteria to accumulate nickel ions","volume":"88","author":"Litvinenko","year":"2019","journal-title":"Microbiology"},{"key":"ref_42","first-page":"473","article-title":"Microbial bioremediation of heavy metal approaches and advancement","volume":"12","author":"Yadav","year":"2025","journal-title":"Adv. Chem. Pollut. Environ. Manag. Prot."},{"key":"ref_43","first-page":"615","article-title":"Biotechnological remedies for the estuarine environment polluted with heavy metals and persistent organic pollutions","volume":"119","author":"Oyetibo","year":"2016","journal-title":"Int. Biodeterior. Biodegrad."},{"key":"ref_44","doi-asserted-by":"crossref","unstructured":"P\u00e1tek, M., Grulich, M., and Ne\u0161vera, J. (2021). Stress response in Rhodococcus strains. Biotechnol. Adv., 53.","DOI":"10.1016\/j.biotechadv.2021.107698"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1167\/14.8.7","article-title":"Experience moderates overlap between object and face recognition, suggesting a common ability","volume":"14","author":"Gauthier","year":"2014","journal-title":"J. Vis."},{"key":"ref_46","doi-asserted-by":"crossref","unstructured":"Ivshina, I.B., Kuyukina, M.S., Litvinenko, L.V., Golysheva, A.A., Kostrikina, N.A., Sorokin, V.V., and Mulyukin, A.L. (2024). Bioaccumulation of molybdate ions by alkanotrophic Rhodococcus leads to significant alterations in cellular ultrastructure and physiology. Ecotoxicol. Environ. Saf., 274.","DOI":"10.1016\/j.ecoenv.2024.116190"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1021\/ac60057a019","article-title":"Phenyl Mercuric or Ethyl Mercuric Compounds","volume":"23","author":"Miller","year":"1951","journal-title":"Anal. Chem."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1038\/217644b0","article-title":"Stimulative vaporization of phenylmercuric acetate by mercury-resistant bacteria","volume":"217","author":"Tonomura","year":"1968","journal-title":"Nature"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.cbi.2015.06.013","article-title":"Elucidation of the defence mechanism in microalgae Chlorella sorokiniana under mercury exposure. Identification of Hg\u2013phytochelatins","volume":"238","year":"2015","journal-title":"Chem.-Biol. Interact."},{"key":"ref_50","first-page":"45","article-title":"Removal and recovery of mercury in vitro using immobilized live biomass of Chlorella sp.","volume":"11","year":"2018","journal-title":"Indian J. Sci. Technol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/j.biortech.2017.06.165","article-title":"Coupling process study of lipid production and mercury bioremediation by biomimetic mineralized microalgae","volume":"243","author":"Peng","year":"2017","journal-title":"Bioresour. Technol."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1007\/s11270-020-04543-9","article-title":"Tolerance capacity of Chlamydomonas VHLR mutants for the toxicity of mercury","volume":"231","author":"Samadani","year":"2020","journal-title":"Water Air Soil Pollut."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"121679","DOI":"10.1016\/j.envpol.2023.121679","article-title":"Phase partitioning of mercury, arsenic, selenium, and cadmium in Chlamydomonas reinhardtii and Arthrospira maxima microcosms","volume":"329","author":"Lown","year":"2023","journal-title":"Environ. Pollut."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1128\/AEM.72.1.361-367.2006","article-title":"Mercury analysis of acid- and alkaline-reduced biological samples: Identification of meta-cinnabar as the major biotransformed compound in algae","volume":"72","author":"Kelly","year":"2006","journal-title":"Appl. Environ. Microbiol."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"139391","DOI":"10.1016\/j.chemosphere.2023.139391","article-title":"Characterization of cellular toxicity induced by sub-lethal inorganic mercury in the marine microalgae Chlorococcum dorsiventrale isolated from a metal-polluted coastal site","volume":"338","author":"Thabet","year":"2023","journal-title":"Chemosphere"},{"key":"ref_56","first-page":"917","article-title":"Efficient bioremediation from metallurgical effluents through the use of microalgae isolated from the amazonic and highlands of Ecuador","volume":"35","year":"2019","journal-title":"Rev. Int. Contam. Ambient."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"112966","DOI":"10.1016\/j.envpol.2019.112966","article-title":"Immobilization of mercury using high-phosphate culture-modified microalgae","volume":"254","author":"Huang","year":"2019","journal-title":"Environ. Pollut."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1128\/aem.57.1.245-247.1991","article-title":"Transformations of inorganic mercury by Candida albicans and Saccharomyces cerevisiae","volume":"57","author":"Yannai","year":"1991","journal-title":"Appl. Environ. Microbiol."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1002\/mbo3.368","article-title":"A new mercury-accumulating Mucor hiemalis strain EH8 from cold sulfidic spring water biofilms","volume":"5","author":"Hoque","year":"2016","journal-title":"Microbiologyopen"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"122638","DOI":"10.1016\/j.jhazmat.2020.122638","article-title":"The bioremediation potentials and mercury(II)-resistant mechanisms of a novel fungus Penicillium spp. DC-F11 isolated from contaminated soil","volume":"396","author":"Chang","year":"2020","journal-title":"J. Hazard. Mater."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"2775","DOI":"10.1007\/s00253-022-11860-y","article-title":"Highly mercury-resistant strains from different Colombian Amazon ecosystems affected by artisanal gold mining activities","volume":"106","author":"Cardona","year":"2022","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"4980","DOI":"10.1016\/j.jece.2018.07.034","article-title":"Assessment of Mercury biosorption by Saccharomyces cerevisiae: Response surface methodology for optimization of low Hg (II) concentrations","volume":"6","author":"Hadiani","year":"2018","journal-title":"J. Environ. Chem. Eng."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1186\/s13568-016-0271-3","article-title":"Mercury removal during growth of mercury tolerant and self-aggregating Yarrowia spp. AMB Express 2016, 6, 99","volume":"6","author":"Oyetibo","year":"2016","journal-title":"AMB Express"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ibiod.2011.12.014","article-title":"Studies on mercury bioremediation by alginate immobilized mercury tolerant Bacillus cereus cells","volume":"71","author":"Sinha","year":"2012","journal-title":"Int. Biodeterior. Biodegrad."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"112549","DOI":"10.1016\/j.marpolbul.2021.112549","article-title":"Deep-sea mercury resistant bacteria from the Central Indian Ocean: A potential candidate for mercury bioremediation","volume":"169","author":"Joshia","year":"2021","journal-title":"Mar. Pollut. Bull."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"5414","DOI":"10.1128\/AEM.69.9.5414-5422.2003","article-title":"Mercury methylation independent of the acetyl-coenzyme a pathway in sulfate-reducing bacteria","volume":"69","author":"Ekstrom","year":"2003","journal-title":"Appl. Environ. Microbiol."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"5746","DOI":"10.1021\/es400414a","article-title":"Effect of dissolved organic matter source and character on microbial Hg methylation in Hg-S-DOM solutions","volume":"47","author":"Graham","year":"2013","journal-title":"Environ. Sci. Technol."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.apsoil.2012.06.004","article-title":"Metal tolerance of rhizobial strains isolated from nodules of herbaceous legumes (Medicago spp. and Trifolium spp.) growing in mercury-contaminated soils","volume":"61","author":"Nonnoi","year":"2012","journal-title":"Appl. Soil Ecol."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"115085","DOI":"10.1016\/j.marpolbul.2023.115085","article-title":"Assessment and characterization of heavy metals resistance bacteria isolated in Southwestern Mediterranean coastal waters (Bou-Ismail Bay): Impacts of anthropogenic activities","volume":"192","author":"Touahir","year":"2023","journal-title":"Mar. Pollut. Bull."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"110818","DOI":"10.1016\/j.ecoenv.2020.110818","article-title":"Endophytic bacteria stimulate mercury phytoremediation by modulating its bioaccumulation and volatilization","volume":"202","author":"Mello","year":"2020","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1128\/AEM.01794-06","article-title":"Biotransformation of Hg (II) by Cyanobacteria","volume":"73","author":"Lefebvre","year":"2007","journal-title":"Appl. Environ. Microbiol."},{"key":"ref_72","doi-asserted-by":"crossref","unstructured":"Mathew, D.C., Ho, Y.-N., Gicana, R.G., Mathew, G.M., Chien, M.-C., and Huang, C.-C. (2015). A rhizosphere-associated symbiont, Photobacterium spp. strain MELD1, and its targeted synergistic activity for phytoprotection against mercury. PLoS ONE, 10.","DOI":"10.1371\/journal.pone.0121178"},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.jes.2016.06.032","article-title":"Mercury remediation potential of a mercury resistant strain Sphingopyxis sp. SE2 isolated from contaminated soil","volume":"51","author":"Mahbub","year":"2017","journal-title":"J. Environ. Sci."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.jenvman.2019.04.017","article-title":"Characterization of mercury-reducing potential bacteria isolated from Keputih non-active sanitary landfill leachate, Surabaya, Indonesia under different saline conditions","volume":"241","author":"Imron","year":"2019","journal-title":"J. Environ. Manag."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1007\/s10532-012-9588-z","article-title":"Isolation and characterization of bacteria from mercury contaminated sites in Rio Grande do Sul, Brazil, and assessment of methylmercury removal capability of a Pseudomonas putida V1 strain","volume":"24","author":"Cabral","year":"2013","journal-title":"Biodegradation"},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1128\/aem.60.3.853-860.1994","article-title":"Identification and characterization of a transmissible linear plasmid from Rhodococcus erythropolis BD2 that encodes isopropylbenzene and trichloroethene catabolism","volume":"60","author":"Dabrock","year":"1994","journal-title":"Appl. Environ. Microbiol."},{"key":"ref_77","doi-asserted-by":"crossref","unstructured":"Kuhl, T., Chowdhury, S.P., Uhl, J., and Rothballer, M. (2021). Genome-based characterization of plant-associated Rhodococcus qingshengii RL1 reveals stress tolerance and plant-microbe interaction traits. Front. Microbiol., 12.","DOI":"10.3389\/fmicb.2021.708605"},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"7834","DOI":"10.1128\/AEM.01982-15","article-title":"Mercury reduction and methyl mercury degradation by the soil bacterium Xanthobacter autotrophicus Py2","volume":"81","author":"Petrus","year":"2015","journal-title":"Appl. Environ. Microbiol."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1021\/bp060075s","article-title":"Co2+, Cu2+ and Zn2+ accumulation by cyanobacterium Spirullina platensis","volume":"22","author":"Vanella","year":"2006","journal-title":"Biotechnol. Prog."},{"key":"ref_80","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/s41514-017-0013-z","article-title":"How does hormesis impact biology, toxicology, and medicine?","volume":"3","author":"Calabrese","year":"2017","journal-title":"Aging. Mech. Disease"},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/j.matpr.2020.02.165","article-title":"Role of microalgae in treatment of acid mine drainage and recovery of valuable metals","volume":"30","author":"Samal","year":"2020","journal-title":"Mater. Today Proc."},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/j.biortech.2016.09.061","article-title":"Augmentation of arsenic enhances lipid yield and defense responses in alga Nannochloropsis sp.","volume":"221","author":"Upadhyay","year":"2016","journal-title":"Bioresour. Technol."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"e07609","DOI":"10.1016\/j.heliyon.2021.e07609","article-title":"Phycoremediation mechanisms of heavy metals using living green microalgae: Physicochemical and molecular approaches for enhancing selectivity and removal capacity","volume":"7","author":"Danouche","year":"2021","journal-title":"Heliyon"},{"key":"ref_84","doi-asserted-by":"crossref","unstructured":"Nateras-Ram\u00edrez, O., Mart\u00ednez-Macias, M.R., S\u00e1nchez-Machado, D.I., L\u00f3pez-Cervantes, J., and Aguilar-Ruiz, R.J. (2022). An overview of microalgae for Cd2+ and Pb2+ biosorption from wastewater. Bioresour. Technol. Rep., 17.","DOI":"10.1016\/j.biteb.2021.100932"},{"key":"ref_85","doi-asserted-by":"crossref","unstructured":"Leong, Y.K., and Chang, J.-S. (2020). Bioremediation of heavy metals using microalgae: Recent advances and mechanisms. Bioresour. Technol., 303.","DOI":"10.1016\/j.biortech.2020.122886"},{"key":"ref_86","doi-asserted-by":"crossref","unstructured":"Shi, K., Gao, Z., Shi, T.-Q., Song, P., Ren, L.-J., Huang, H., and Ji, X.-J. (2017). Reactive oxygen species-mediated cellular stress response and lipid accumulation in oleaginous microorganisms: The state of the art and future perspectives. Front. Microbiol., 8.","DOI":"10.3389\/fmicb.2017.00793"},{"key":"ref_87","doi-asserted-by":"crossref","unstructured":"Balzano, S., Sardo, A., Blasio, M., Chahine, T.B., dell\u2019Anno, F., and Sansone, C. (2020). Microalgal metallothioneins and phytochelatins and their potential use in bioremediation. Front. Microbiol., 11.","DOI":"10.3389\/fmicb.2020.00517"},{"key":"ref_88","first-page":"1","article-title":"Bioremediation of textile dye using white-rot fungi: A review","volume":"5","author":"Jebapriya","year":"2013","journal-title":"Int. J. Curr. Res. Rev."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"21","DOI":"10.21608\/mb.2020.32802.1016","article-title":"Beneficial fungal communities from different habitats and their roles in plant growth promotion and soil health","volume":"5","author":"Devi","year":"2020","journal-title":"Microbial. Biosyst."},{"key":"ref_90","doi-asserted-by":"crossref","unstructured":"Panpatte, D.G., and Jhala, Y.K. (2021). Fungal-mediated bioremediation of heavy metal\u2013polluted environment. Microbial Rejuvenation of Polluted Environment, Springer.","DOI":"10.1007\/978-981-15-7455-9"},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1111\/j.1574-6968.2005.00044.x","article-title":"Extracellular and cellular mechanisms sustaining metal tolerance in ectomycorrhizal fungi","volume":"254","author":"Bellion","year":"2006","journal-title":"FEMS Microbiol. Lett."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"384","DOI":"10.4172\/1948-5948.1000243","article-title":"Heavy metal contaminants removal from wastewater using the potential filamentous fungi biomass: A review","volume":"7","author":"Siddiquee","year":"2015","journal-title":"J. Microb. Biochem Technol."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"2315","DOI":"10.1128\/AEM.69.4.2313-2320.2003","article-title":"Heavy metal resistance of biofilm and planktonic Pseudomonas aeruginosa","volume":"69","author":"Teitzel","year":"2003","journal-title":"Appl. Environ. Microbiol."},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"419","DOI":"10.3390\/ma9060418","article-title":"Roles of extracellular polysaccharides and biofilm formation in heavy metal resistance of Rhizobia","volume":"9","author":"Nocelli","year":"2016","journal-title":"Materials"},{"key":"ref_95","first-page":"1371","article-title":"Effects of extracellular polymeric substances on the bioaccumulation of mercury and its toxicity toward the cyanobacterium Microcystis aeruginosa","volume":"49","author":"Chen","year":"2014","journal-title":"J. Environ. Sci. Health Tox. Hazard. Subst. Environ. Eng."},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"627","DOI":"10.2175\/106143014X13975035525465","article-title":"Methylmercury accumulation and toxicity to cyanobacteria: Implications of extracellural polymeric substances and growth properties","volume":"86","author":"Chen","year":"2014","journal-title":"Water Environ. Res."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"100197","DOI":"10.1016\/j.envc.2021.100197","article-title":"Molecular mechanisms underlying heavy metal uptake, translocation and tolerance in hyperaccumulators-an analysis: Heavy metal tolerance in hyperaccumulators","volume":"4","author":"Pasricha","year":"2021","journal-title":"Environ. Chall."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.ecoenv.2016.11.002","article-title":"Phytochelatin synthesis in Dunaliella salina induced by arsenite and arsenate under various phosphate regimes","volume":"136","author":"Wang","year":"2017","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"ref_99","doi-asserted-by":"crossref","unstructured":"Barra, L., and Greco, S. (2023). The Potential of microalgae in phycoremediation submitted. Microalgae\u2014Current and Potential Applications, IntechOpen.","DOI":"10.5772\/intechopen.1003212"},{"key":"ref_100","doi-asserted-by":"crossref","unstructured":"Shivaji, S., and Dronamaraju, S.V.L. (2019). Scenedesnus rotundus isolated from the petroleum effluent employs alternate mechanisms of tolerance to elevated levels of Cadmium and Zinc. Sci. Rep., 9.","DOI":"10.1038\/s41598-019-44374-1"},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"104460","DOI":"10.1016\/j.jece.2020.104460","article-title":"Heavy metals phycoremediation using tolerant green microalgae: Enzymatic and non-enzymatic antioxidant systems for the management of oxidative stress","volume":"8","author":"Danouche","year":"2020","journal-title":"J. Environ. Chem. Eng."},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"15826","DOI":"10.3390\/ijms131215826","article-title":"MicroRNAs in metal stress: Specific roles or secondary responses?","volume":"13","author":"Gielen","year":"2012","journal-title":"In. J. Mol. Sci."},{"key":"ref_103","doi-asserted-by":"crossref","unstructured":"Beauvais-Fl\u00fcck, R., Slaveykova, V.I., and Cosio, C. (2017). Cellular toxicity pathways of inorganic and methyl mercury in the green microalga Chlamydomonas reinhardtii. Sci. Rep., 7.","DOI":"10.1038\/s41598-017-08515-8"},{"key":"ref_104","doi-asserted-by":"crossref","unstructured":"Chakravorty, M., Nanda, M., Bisht, B., Sharma, R., Kumar, S., Mishra, A., Vlaskin, M.S., Chauhan, P.K., and Kumar, V. (2023). Heavy metal tolerance in microalgae: Detoxification mechanisms and applications. Aquat. Toxicol., 260.","DOI":"10.1016\/j.aquatox.2023.106555"},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"2770","DOI":"10.1016\/j.biortech.2009.01.002","article-title":"Chromium removal from a real tanning effluent by autochthonous and allochthonous fungi","volume":"100","author":"Prigione","year":"2009","journal-title":"Bioresour. Technol."},{"key":"ref_106","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1111\/j.1574-6968.2001.tb10903.x","article-title":"Nutritional influence on fungal colony growth and biomass distribution in response to toxic metals","volume":"204","author":"Gadd","year":"2001","journal-title":"FEMS Microbiol. Lett."},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1039\/c2mt20041d","article-title":"Proteomic analysis of proteins secreted by Botrytis cinerea in response to heavy metal toxicity","volume":"4","author":"Cherrad","year":"2012","journal-title":"Metallomics"},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1039\/c9mt00081j","article-title":"Role of the Fusarium oxysporum metallothionein Mt1 in resistance to metal toxicity and virulence","volume":"11","author":"Guarro","year":"2019","journal-title":"Metallomics"},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/s40201-015-0176-0","article-title":"Highly cadmium tolerant fungi: Their tolerance and removal potential","volume":"13","author":"Soleimani","year":"2015","journal-title":"J. Environ. Health Sci. Eng."},{"key":"ref_110","doi-asserted-by":"crossref","unstructured":"Gajewska, J., Azzahra, N.A., Bing\u00f6l, \u00d6.A., Izbia\u0144ska-Jankowska, K., Jelonek, T., Deckert, J., Floryszak-Wieczorek, J., and Arasimowicz-Jelonek, M. (2020). Cadmium stress reprograms ROS\/RNS homeostasis in Phytophthora infestans (Mont.) de Bary. Int. J. Mol. Sci., 21.","DOI":"10.3390\/ijms21218375"},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1007\/s12010-014-1298-z","article-title":"The effect of heavy metal-induced oxidative stress on the enzymes in white rot fungus Phanerochaete chrysosporium","volume":"175","author":"Zhang","year":"2015","journal-title":"Biotechnol. Appl. Biochem."},{"key":"ref_112","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1007\/s00284-014-0751-0","article-title":"Organic acids induce tolerance to zinc- and copper-exposed fungi under various growth conditions","volume":"70","author":"Sazanova","year":"2015","journal-title":"Curr. Microbiol."},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/j.soilbio.2004.10.013","article-title":"Solubilization of toxic metal minerals and metal tolerance of mycorrhizal fungi","volume":"37","author":"Fomina","year":"2005","journal-title":"Soil. Biol. Biochem."},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1111\/1751-7915.12117","article-title":"Siderophores in environmental research: Roles and applications","volume":"7","author":"Ahmed","year":"2014","journal-title":"Microb. Biotechnol."},{"key":"ref_115","first-page":"2030","article-title":"Pyrene degradation and copper and zinc uptake by Fusarium solani and Hypocrea lixii isolated from petrol station soil","volume":"108","author":"Hong","year":"2010","journal-title":"J. Appl. Microbiol."},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.ecoenv.2017.08.058","article-title":"Adsorption characteristics of Copper (II), Zinc (II) and Mercury (II) by four kinds of immobilized fungi residues","volume":"147","author":"Li","year":"2018","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"ref_117","doi-asserted-by":"crossref","unstructured":"Kovalchuk, A., and Driessen, A.J.M. (2010). Phylogenetic analysis of fungal ABC transporters. BMC Genom., 11.","DOI":"10.1186\/1471-2164-11-177"},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1002\/iub.1618","article-title":"Copper metallothioneins","volume":"69","author":"Calvo","year":"2017","journal-title":"IUBMB Life"},{"key":"ref_119","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1099\/mic.0.080218-0","article-title":"Differential expression of metallothioneins in response to heavy metals and their involvement in metal tolerance in the symbiotic basidiomycete Laccaria bicolor","volume":"160","author":"Reddy","year":"2014","journal-title":"Microbiology"},{"key":"ref_120","doi-asserted-by":"crossref","first-page":"100369","DOI":"10.1016\/j.eti.2019.100369","article-title":"Bioremediation of heavy metals by microbial process","volume":"14","author":"Verma","year":"2019","journal-title":"Environ. Technol. Innov."},{"key":"ref_121","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/s12275-018-7475-y","article-title":"Vacuolar zinc transporter Zrc1 is required for detoxification of excess intracellular zinc in the human fungal pathogen Cryptococcus neoformans","volume":"56","author":"Cho","year":"2018","journal-title":"J. Microbiol."},{"key":"ref_122","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/j.carres.2006.01.010","article-title":"Structural analysis of an extracellular polysaccharide produced by a benzene tolerant bacterium Rhodococcus sp. 33","volume":"341","author":"Urai","year":"2006","journal-title":"Carbohydr. Res."},{"key":"ref_123","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1071\/MA18041","article-title":"Hydrocarbon and metal-polluted soil bioremediation: Progress and challenges","volume":"39","author":"Kuyukina","year":"2018","journal-title":"Microbiol. Aust."},{"key":"ref_124","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1007\/s10529-004-3184-1","article-title":"Comparative study of Cr (VI) uptake and reduction in industrial effluent by Ochrobacterium intermedium and Brevibacterium sp.","volume":"26","author":"Faisal","year":"2004","journal-title":"Biotechnol. Lett."},{"key":"ref_125","doi-asserted-by":"crossref","first-page":"1556","DOI":"10.1186\/s13068-018-1337-z","article-title":"Lipid metabolism of phenol-tolerant Rhodococcus opacus strains for lignin bioconversion","volume":"11","author":"Henson","year":"2018","journal-title":"Biotechnol. Biofuels."},{"key":"ref_126","doi-asserted-by":"crossref","first-page":"7019","DOI":"10.1128\/AEM.69.12.7019-7027.2003","article-title":"Carbon source-induced modifications in the mycolic acid content and cell wall permeability of Rhodococcus erythropolis E1","volume":"69","author":"Sokolovska","year":"2003","journal-title":"Appl. Environ. Microbiol."},{"key":"ref_127","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0012-8252(00)00008-8","article-title":"Accumulation of metals by microorganisms-processes and importance for soil systems","volume":"51","author":"Ledin","year":"2000","journal-title":"Earth-Sci. Rev."},{"key":"ref_128","doi-asserted-by":"crossref","first-page":"173044","DOI":"10.1016\/j.scitotenv.2024.173044","article-title":"Siderophores and metallophores: Metal complexation weapons to fight environmental pollution","volume":"932","author":"Gomes","year":"2024","journal-title":"Sci. Total Environ."},{"key":"ref_129","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1007\/s10534-014-9739-2","article-title":"Siderophore production by actinobacteria","volume":"27","author":"Wang","year":"2014","journal-title":"BioMetals"},{"key":"ref_130","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/S0168-6445(03)00046-9","article-title":"Bacterial mercury resistance from atoms to ecosystems","volume":"27","author":"Barkay","year":"2003","journal-title":"FEMS Microbiol. Rev."},{"key":"ref_131","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1007\/s10646-010-0514-z","article-title":"Mercury-induced oxidative stress and impact on antioxidant enzymes in Chlamydomonas reinhardtii","volume":"19","author":"Elbaz","year":"2010","journal-title":"Ecotoxicology"},{"key":"ref_132","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1007\/s10534-013-9679-2","article-title":"The impact of ionic mercury on antioxidant defenses in two mercury-sensitive anaerobic bacteria","volume":"26","author":"Wang","year":"2013","journal-title":"BioMetals"},{"key":"ref_133","doi-asserted-by":"crossref","first-page":"e1500675","DOI":"10.1126\/sciadv.1500675","article-title":"Global prevalence and distribution of genes and microorganisms involved in mercury methylation","volume":"1","author":"Podar","year":"2015","journal-title":"Sci. Adv."},{"key":"ref_134","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.scitotenv.2005.02.036","article-title":"Total mercury and methylmercury accumulation in periphyton of Boreal Shield lakes: Influence of watershed physiographic characteristics","volume":"355","author":"Desrosiers","year":"2006","journal-title":"Sci. Total Environ."},{"key":"ref_135","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/01490450802599227","article-title":"Overview of mercury methylation capacities among anaerobic bacteria including representatives of the sulphate-reducers: Implications for environmental studies","volume":"26","author":"Monperrus","year":"2009","journal-title":"Geomicrobiol. J."},{"key":"ref_136","doi-asserted-by":"crossref","first-page":"e00002-21","DOI":"10.1128\/mra.00002-21","article-title":"Complete genome sequence of Desulfobulbus oligotrophicus Prop6, an anaerobic Deltabacterota strain that lacks mercury methylation capability","volume":"10","author":"Podar","year":"2021","journal-title":"Microbiol. Resour. Announc."},{"key":"ref_137","doi-asserted-by":"crossref","first-page":"7919","DOI":"10.1128\/AEM.01602-06","article-title":"Mercury methylation by dissimilatory iron-reducing bacteria","volume":"72","author":"Kerin","year":"2006","journal-title":"Appl. Environ. Microbiol."},{"key":"ref_138","doi-asserted-by":"crossref","first-page":"e01774-18","DOI":"10.1128\/AEM.01774-18","article-title":"Methanogens and iron-reducing bacteria: The overlooked members of mercury-methylating microbial communities in Boreal lakes","volume":"84","author":"Bravo","year":"2018","journal-title":"Appl. Environ. Microbiol."},{"key":"ref_139","unstructured":"Liu, G., Cai, Y., and O\u2019Driscoll, N. (2012). Microbial Transformations in the Mercury Cycle. Environmental Chemistry and Toxicology of Mercury, John Wiley and Sons, Inc."},{"key":"ref_140","first-page":"21","article-title":"Analysis of waste waters toxicity and detoxication during their biological treatment","volume":"6","author":"Ignatenko","year":"2022","journal-title":"Technol. Elimin. Chem. Hazards"},{"key":"ref_141","first-page":"1101","article-title":"Isolation and characterization of environmental bacteria capable of extracellular biosorption of mercury","volume":"78","author":"Lombard","year":"2012","journal-title":"Appl. Environ. Microbiol."},{"key":"ref_142","doi-asserted-by":"crossref","first-page":"8715","DOI":"10.1073\/pnas.1105781108","article-title":"Active transport, substrate specificity, and methylation of Hg (II) in anaerobic bacteria","volume":"108","author":"Schaefer","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_143","doi-asserted-by":"crossref","unstructured":"Boyd, E.S., and Barkay, T. (2012). The mercury resistance operon: From an origin in a geothermal environment to an efficient detoxification machine. Front. Microbiol., 3.","DOI":"10.3389\/fmicb.2012.00349"},{"key":"ref_144","doi-asserted-by":"crossref","unstructured":"Christakis, C.A., Barkay, T., and Boyd, E.S. (2021). Expanded diversity and phylogeny of mer genes broadens mercury resistance paradigms and reveals an origin for MerA among thermophilic archaea. Front. Microbiol., 12.","DOI":"10.3389\/fmicb.2021.682605"},{"key":"ref_145","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.resmic.2014.02.001","article-title":"CadA of Mesorhizobium metallidurans isolated from a zinc-rich mining soil is a PIB-2-type ATPase involved in cadmium and zinc resistance","volume":"165","author":"Maynaud","year":"2014","journal-title":"Res. Microbiol."},{"key":"ref_146","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.biochi.2017.09.016","article-title":"Functional efficiency of MerA protein among diverse mercury resistant bacteria for efficient use in bioremediation of inorganic mercury","volume":"142","author":"Dash","year":"2017","journal-title":"Biochimie"},{"key":"ref_147","doi-asserted-by":"crossref","unstructured":"Fagorzi, C., Checcucci, A., diCenzo, G.C., Debiec-Andrzejewska, K., Dziewit, L., Pini, F., and Mengoni, A. (2018). Harnessing Rhizobia to improve heavy-metal phytoremediation by legumes. Genes, 9.","DOI":"10.3390\/genes9110542"},{"key":"ref_148","doi-asserted-by":"crossref","first-page":"e00176-20","DOI":"10.1128\/AEM.00176-20","article-title":"Genome-resolved metagenomics and detailed geochemical speciation analyses yield new insights into microbial mercury cycling in geothermal springs","volume":"86","author":"Gionfriddo","year":"2020","journal-title":"Appl. Environ. Microbiol."},{"key":"ref_149","doi-asserted-by":"crossref","first-page":"123016","DOI":"10.1016\/j.envpol.2023.123016","article-title":"Tailored bacteria tackling with environmental mercury: Inspired by natural mercuric detoxification operons","volume":"341","author":"Hui","year":"2024","journal-title":"Environ. Pollut."},{"key":"ref_150","doi-asserted-by":"crossref","unstructured":"Zhao, M., Zheng, G., Kang, X., Zhang, X., Guo, J., Wang, S., Chen, Y., and Xue, L. (2023). Aquatic bacteria rheinheimera tangshanensis new ability for mercury pollution removal. Int. J. Mol. Sci., 24.","DOI":"10.3390\/ijms24055009"},{"key":"ref_151","doi-asserted-by":"crossref","first-page":"2904","DOI":"10.1111\/j.1462-2920.2010.02260.x","article-title":"A thermophilic bacterial origin and subsequent constraints by redox, light and salinity on the evolution of the microbial mercuric reductase","volume":"12","author":"Barkay","year":"2010","journal-title":"Environ. Microbiol."},{"key":"ref_152","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1038\/ngeo2629","article-title":"A physiological role for Hg (II) during phototrophic growth","volume":"9","author":"Gregoire","year":"2016","journal-title":"Nat. Geosci."},{"key":"ref_153","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1038\/220173a0","article-title":"Synthesis of methyl-mercury compounds by extracts of a methanogenic bacterium","volume":"220","author":"Wood","year":"1968","journal-title":"Nature"},{"key":"ref_154","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1128\/am.30.3.424-432.1975","article-title":"Formation of methyl mercury by bacteria","volume":"30","author":"Hamdy","year":"1975","journal-title":"Appl. Microbiol."},{"key":"ref_155","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1002\/etc.395","article-title":"Simultaneous determination of mercury methylation and demethylation capacities of various sulfate-reducing bacteria using species-specific isotopic tracers","volume":"30","author":"Bridou","year":"2011","journal-title":"Environ. Toxicol. Chem."},{"key":"ref_156","doi-asserted-by":"crossref","unstructured":"Tang, Z., Yu, J., Fan, F., Wang, S., Wang, D., and Huang, Y. (2025). Effects of redox-modified biochar on mercury reduction and methylation on electron transfer in Geobacter sulfurreducens PCA. Bioresour. Technol., 427.","DOI":"10.1016\/j.biortech.2025.132423"},{"key":"ref_157","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/2191-0855-3-41","article-title":"Mercurial-resistance determinants in Pseudomonas strain K-62 plasmid pMR68","volume":"3","author":"Sone","year":"2013","journal-title":"AMB Express"},{"key":"ref_158","doi-asserted-by":"crossref","unstructured":"Bhat, A., Sharma, R., Desigan, K., Lucas, M.M., Mishra, A., Bowers, R.M., Woyke, T., Epstein, B., Tiffin, P., and Pueyo, J.J. (2024). Horizontal gene transfer of the Mer operon is associated with large effects on the transcriptome and increased tolerance to mercury in nitrogen-fixing bacteria. BMC Microbiol., 24.","DOI":"10.1186\/s12866-024-03391-5"},{"key":"ref_159","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1023\/A:1015875216095","article-title":"Efficient uptake of cesium ions by Rhodococcus cells","volume":"71","author":"Ivshina","year":"2002","journal-title":"Microbiology"},{"key":"ref_160","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1134\/S1067413613020082","article-title":"Adaptive mechanisms of nonspecific resistance to heavy metal ions in alkanotrophic actinobacteria","volume":"44","author":"Ivshina","year":"2013","journal-title":"Russ. J. Ecol."},{"key":"ref_161","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.mimet.2004.03.006","article-title":"Methods evaluating vanadium tolerance in bacteria isolated from crude oil contaminated land","volume":"58","author":"Bell","year":"2004","journal-title":"J. Microbiol. Methods"},{"key":"ref_162","doi-asserted-by":"crossref","unstructured":"Presentato, A., Piacenza, E., Turner, R.J., Zannoni, D., and Cappelletti, M. (2020). Processing of metals and metalloids by Actinobacteria: Cell resistance mechanisms and synthesis of metal(loid)-based nanostructures. Microorganisms, 8.","DOI":"10.3390\/microorganisms8122027"},{"key":"ref_163","doi-asserted-by":"crossref","unstructured":"Carpenter, J.S., Bai, C., Escobedo, J.P., Hwang, J.-Y., Ikhmayies, S., Li, B., Li, J., Monteiro, S.N., Peng, Z., and Zhang, M. (2015). Recovery of mercury and lead from wastewater by sulfide precipitation-flotation. Characterization of Minerals, Metals, and Materials, Springer Cham. [2nd ed.].","DOI":"10.1002\/9781119093404"},{"key":"ref_164","doi-asserted-by":"crossref","first-page":"134900","DOI":"10.1016\/j.jclepro.2022.134900","article-title":"Simultaneous mercury removal from wastewater and hydrogen sulfide scavenging from sour natural gas using a single unit operation","volume":"380","author":"Onaizi","year":"2022","journal-title":"J. Clean. Prod."},{"key":"ref_165","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.envpol.2005.06.005","article-title":"Stabilization of mercury-containing wastes using sulfide","volume":"139","author":"Piao","year":"2006","journal-title":"Environ. Pollut."},{"key":"ref_166","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1016\/S1003-6326(15)63647-0","article-title":"Separation and enrichment of elemental sulfur and mercury from hydrometallurgical zinc residue using sodium sulfide","volume":"25","author":"Wang","year":"2015","journal-title":"Trans. Nonferrous Met. Soc. China"},{"key":"ref_167","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1007\/s00253-003-1322-7","article-title":"Pilot plant for bioremediation of mercury-containing industrial wastewater","volume":"62","year":"2003","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"ref_168","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.jenvman.2010.11.011","article-title":"Removal of heavy metal ions from wastewaters: A Review","volume":"92","author":"Fu","year":"2011","journal-title":"J. Environ. Manag."},{"key":"ref_169","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.cis.2011.04.005","article-title":"Industrial wastes as low-cost potential adsorbents for the treatment of wastewater laden with heavy metals","volume":"166","author":"Ahmaruzzaman","year":"2011","journal-title":"Adv. Colloid Interface Sci."},{"key":"ref_170","first-page":"335","article-title":"Environmental impacts of mercury and its detoxification from aqueous solutions","volume":"6","author":"Okoronkwo","year":"2007","journal-title":"Afr. J. Biotechnol."},{"key":"ref_171","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.memsci.2007.09.027","article-title":"Removal of heavy metal ions from aqueous solutions by filtration with a novel complexing membrane containing poly(ethyleneimine) in a poly(vinyl alcohol) matrix","volume":"307","author":"Bessbousse","year":"2008","journal-title":"J. Membr. Sci."},{"key":"ref_172","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/j.scitotenv.2014.02.067","article-title":"Spatial distribution and accumulation of Hg in soil surrounding a Zn\/Pb smelter","volume":"496","author":"Wu","year":"2014","journal-title":"Sci. Total Environ."},{"key":"ref_173","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/S0147-6513(02)00122-7","article-title":"Use of chlorophyll fluorescence in metal-stress research: A case study with the green microalga Scenedesmus","volume":"55","author":"Mallick","year":"2003","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"ref_174","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.biortech.2013.08.149","article-title":"Development of experimental design approach and ANN-based models for determination of Cr(VI) ions uptake rate from aqueous solution onto the solid biodiesel waste residue","volume":"148","author":"Shanmugaprakash","year":"2013","journal-title":"Bioresour. Technol."},{"key":"ref_175","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1007\/s10811-020-02052-0","article-title":"Evaluation of mercury adsorption and removal efficacy of pulverized Chlorella (C. vulgaris)","volume":"32","author":"Yadav","year":"2020","journal-title":"J. Appl. Phycol."},{"key":"ref_176","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.algal.2017.04.027","article-title":"Dynamic interactions of Hg(II) with the surface of green microalgae Chlamydomonas reinhardtii studied by stripping chronopotentiometry","volume":"24","year":"2017","journal-title":"Algal Res."},{"key":"ref_177","doi-asserted-by":"crossref","unstructured":"Torres, M.J., Bellido-Pedraza, C.M., and Llamas, A. (2024). Applications of the microalgae chlamydomonas and its bacterial consortia in detoxification and bioproduction. Life, 14.","DOI":"10.20944\/preprints202406.1016.v1"},{"key":"ref_178","doi-asserted-by":"crossref","unstructured":"Gojkovic, Z., Simansky, S., Sanabria, A., M\u00e1rov\u00e1, I., Garbayo, I., and V\u00edlchez, C. (2023). Interaction of naturally occurring phytoplankton with the biogeochemical cycling of mercury in aquatic environments and its effects on global Hg pollution and public health. Microorganisms, 11.","DOI":"10.3390\/microorganisms11082034"},{"key":"ref_179","doi-asserted-by":"crossref","first-page":"3031","DOI":"10.1016\/j.procbio.2005.02.004","article-title":"Removal of copper (II) ions from aqueous solution by biosorption onto agricultural waste sugar beet pulp","volume":"40","author":"Aksu","year":"2005","journal-title":"Process Biochem."},{"key":"ref_180","first-page":"1403","article-title":"Biosorption of copper (II) from aqueous solution by mycelial pellets of Rhizopus oryzae","volume":"11","author":"Fu","year":"2012","journal-title":"Afr. J. Biotechnol."},{"key":"ref_181","doi-asserted-by":"crossref","first-page":"213","DOI":"10.15415\/jnp.2014.12017","article-title":"Potential of some fungal and bacterial species in bioremediation of heavy metals","volume":"1","author":"Kumar","year":"2014","journal-title":"J. Nucl. Phys. Mater. Sci. Radiat."},{"key":"ref_182","doi-asserted-by":"crossref","unstructured":"Pande, V., Pandey, S.C., Sati, D., Bhatt, P., and Samant, M. (2022). Microbial interventions in bioremediation of heavy metal contaminants in agroecosystem. Front. Microbiol., 13.","DOI":"10.3389\/fmicb.2022.824084"},{"key":"ref_183","doi-asserted-by":"crossref","first-page":"e2214513119","DOI":"10.1073\/pnas.2214513119","article-title":"Bioremediation of mercury-polluted soil and water by the plant symbiotic fungus Metarhizium robertsii","volume":"119","author":"Wu","year":"2022","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_184","doi-asserted-by":"crossref","first-page":"109623","DOI":"10.1016\/j.ecoenv.2019.109623","article-title":"Localization, ligand environment, bioavailability and toxicity of mercury in Boletus spp. and Scutiger pes-caprae mushrooms","volume":"184","author":"Debeljak","year":"2019","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"ref_185","first-page":"1","article-title":"Oxidative stress, chromium-resistance and uptake by fungi: Isolated from industrial wastewater","volume":"60","author":"Elahi","year":"2017","journal-title":"Braz. Arch. Biol. Technol."},{"key":"ref_186","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s00253-017-8239-z","article-title":"Binding of Hg by bacterial extracellular polysaccharide: A possible role in Hg tolerance","volume":"101","author":"Cruz","year":"2017","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"ref_187","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.ecolind.2016.12.004","article-title":"Mercury toxicity to terrestrial biota","volume":"74","author":"Mahbub","year":"2017","journal-title":"Ecol. Indic."},{"key":"ref_188","first-page":"92","article-title":"Operon mer: Bacterial resistance to mercury and potential for bioremediation of contaminated environments","volume":"2","author":"Nascimento","year":"2003","journal-title":"Genet. Mol. Res."},{"key":"ref_189","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/S1003-6326(09)60170-9","article-title":"Isolation, characterizationand extraction of mer gene of Hg2+ resisting strain D2","volume":"20","author":"Zeng","year":"2010","journal-title":"Trans. Nonferrous Met. Soc. China"},{"key":"ref_190","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1289\/ehp.7861","article-title":"The roles of serum selenium and selenoproteins on mercury toxicity in environmental and occupational exposure","volume":"114","author":"Chen","year":"2006","journal-title":"Environ. Health Perspect."},{"key":"ref_191","doi-asserted-by":"crossref","first-page":"e00183-19","DOI":"10.1128\/mBio.00183-19","article-title":"Superoxide dismutase and pseudocatalase increase tolerance to Hg(II) in Thermus thermophilus HB27 by maintaining the reduced bacillithiol pool","volume":"10","author":"Norambuena","year":"2019","journal-title":"mBio"},{"key":"ref_192","doi-asserted-by":"crossref","first-page":"130524","DOI":"10.1016\/j.jclepro.2022.130524","article-title":"Mercury bioremediation in aquatic environment by genetically modified bacteria with self-controlled biosecurity circuit","volume":"337","author":"Xue","year":"2022","journal-title":"J. Clean. Prod."},{"key":"ref_193","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1016\/S0025-326X(02)00174-1","article-title":"Mercury and lead tolerance in hypersaline sulfate-reducing bacteria","volume":"44","author":"Harithsa","year":"2002","journal-title":"Mar. Pollut. Bull."},{"key":"ref_194","doi-asserted-by":"crossref","first-page":"130629","DOI":"10.1016\/j.chemosphere.2021.130629","article-title":"Reduction and bacterial adsorption of dissolved mercuric ion by indigenous bacteria at the Oak Ridge Reservation site","volume":"280","author":"Li","year":"2021","journal-title":"Chemosphere"},{"key":"ref_195","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/s10533-017-0408-8","article-title":"Methylmercury and methane production potentials in North Carolina Piedmont stream sediments","volume":"137","author":"Blum","year":"2018","journal-title":"Biogeochemistry"},{"key":"ref_196","doi-asserted-by":"crossref","first-page":"e01918-14","DOI":"10.1128\/mBio.01918-14","article-title":"Selection of a multidrug resistance plasmid by sublethal levels of antibiotics and heavy metals","volume":"5","author":"Gullberg","year":"2014","journal-title":"mBio"},{"key":"ref_197","doi-asserted-by":"crossref","first-page":"116569","DOI":"10.1016\/j.envpol.2021.116569","article-title":"Heavy metal pollution promotes antibiotic resistance potential in the aquatic environment","volume":"274","author":"Komijani","year":"2021","journal-title":"Environ. Pollut."},{"key":"ref_198","first-page":"206","article-title":"Identification of mercury-resistant Streptomyces isolated from Cyperus rotundus L. rhizosphere and molecular cloning of mercury (II) reductase gene","volume":"26","author":"Putri","year":"2021","journal-title":"J. Biotechnol."},{"key":"ref_199","doi-asserted-by":"crossref","first-page":"e2912","DOI":"10.7717\/peerj.2912","article-title":"Genomic data mining of the marine actinobacteria Streptomyces sp. H-KF8 unveils insights into multi-stress related genes and metabolic pathways involved in antimicrobial synthesis","volume":"5","author":"Undabarrena","year":"2017","journal-title":"PeerJ"},{"key":"ref_200","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1099\/ijs.0.024018-0","article-title":"Streptomyces zinciresistens sp. nov., a zinc-resistant actinomycete isolated from soil from a copper and zinc mine","volume":"61","author":"Lin","year":"2011","journal-title":"Int. J. Syst. Evol. Microbiol."},{"key":"ref_201","doi-asserted-by":"crossref","first-page":"115057","DOI":"10.1016\/j.envpol.2020.115057","article-title":"Long-lasting effect of mercury contamination on the soil microbiota and its co-selection of antibiotic resistance","volume":"265 Pt B","author":"Mahbub","year":"2020","journal-title":"Environ. Pollut."},{"key":"ref_202","doi-asserted-by":"crossref","unstructured":"Hall, J.P.J., Harrison, E., P\u00e4rn\u00e4nen, K., Virta, M., and Brockhurst, M.A. (2020). The impact of mercury selection and conjugative genetic elements on community structure and resistance gene transfer. Front. Microbiol., 11.","DOI":"10.3389\/fmicb.2020.01846"},{"key":"ref_203","doi-asserted-by":"crossref","first-page":"4304","DOI":"10.1021\/es049895w","article-title":"Role of the bacterial organomercury lyase (MerB) in controlling methylmercury accumulation in mercury-contaminated natural waters","volume":"38","author":"Schaefer","year":"2004","journal-title":"Environ. Sci. Technol."},{"key":"ref_204","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1107\/S0907444902008326","article-title":"Crystallization and preliminary analysis of Escherichia coli YodA","volume":"58","author":"David","year":"2002","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"ref_205","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.bbrc.2007.09.094","article-title":"Zinc dependence of zinT (yodA) mutants and binding of zinc, cadmium and mercury by ZinT","volume":"364","author":"Kershaw","year":"2007","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"ref_206","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1016\/j.chemosphere.2007.08.015","article-title":"Comparative study of chromium biosorption by red, green and brown seaweed biomass","volume":"70","author":"Murphy","year":"2008","journal-title":"Chemosphere"},{"key":"ref_207","doi-asserted-by":"crossref","first-page":"1778","DOI":"10.1016\/S1001-0742(10)60650-X","article-title":"Biosorption of mercury by Macrocystis pyrifera and Undaria pinnatifida: Influence of zinc, cadmium and nickel","volume":"23","author":"Plaza","year":"2011","journal-title":"J. Environ. Sci. (China)"},{"key":"ref_208","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0045-6535(98)00591-8","article-title":"Production of methylated mercury, lead, and cadmium by marine bacteria as a significant natural source for atmospheric heavy metals in polar regions","volume":"39","author":"Pongratz","year":"1999","journal-title":"Chemosphere"}],"container-title":["Microorganisms"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-2607\/13\/6\/1350\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T17:49:43Z","timestamp":1760032183000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-2607\/13\/6\/1350"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,10]]},"references-count":208,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2025,6]]}},"alternative-id":["microorganisms13061350"],"URL":"https:\/\/doi.org\/10.3390\/microorganisms13061350","relation":{},"ISSN":["2076-2607"],"issn-type":[{"value":"2076-2607","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,10]]}}}