{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T22:48:29Z","timestamp":1791067709523,"version":"4.1.0"},"reference-count":56,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T00:00:00Z","timestamp":1755129600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100016993","name":"Ministry of Infrastructure and Water Management","doi-asserted-by":"publisher","award":["M\/270106"],"award-info":[{"award-number":["M\/270106"]}],"id":[{"id":"10.13039\/501100016993","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100016993","name":"Ministry of Infrastructure and Water Management","doi-asserted-by":"publisher","award":["9-2-21.C"],"award-info":[{"award-number":["9-2-21.C"]}],"id":[{"id":"10.13039\/501100016993","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Netherlands Food and Consumer Product Safety Authority","award":["M\/270106"],"award-info":[{"award-number":["M\/270106"]}]},{"name":"Netherlands Food and Consumer Product Safety Authority","award":["9-2-21.C"],"award-info":[{"award-number":["9-2-21.C"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microorganisms"],"abstract":"<jats:p>Vibrio species are part of the indigenous microbial flora in marine, brackish and fresh water in moderate and tropical climates that thrive and multiply in water at elevated water temperatures. The number of human non-cholera Vibrio infections due to exposure to contaminated surface water increases worldwide. To study possible climate change-related changes in Vibrio concentrations, prevalent species, and risks of illness, water samples from coastal and inland water bodies in the Netherlands were tested in 2019\u20132021. Data were combined with data from previous studies in 2009\u20132012 in order to develop a regression model to predict current and future risks of Vibrio illness. Year-to-year and site-specific variations in Vibrio concentrations and water temperature were observed, but there was no trend of increasing Vibrio concentrations or water temperature over time. In 2019\u20132021, Vibrio species distribution had not changed since 2009\u20132012; V. alginolyticus and V. parahaemolyticus were still the dominant species. Statistical analysis demonstrated a significant effect of water temperature on Vibrio concentrations. The model predicted a concentration increase of a factor of 1.5 for each degree Celsius temperature increase. Predicted risks of illness were higher at higher water temperatures, and higher for children than for adults. Based on the most recent climate change scenarios for the Netherlands, the risks of Vibrio illness will increase with factors ranging from 1.6 to 7.6 in 2050 and 2100. These outcomes warrant adequate information about Vibrio risks to water managers, public health workers and the general public.<\/jats:p>","DOI":"10.3390\/microorganisms13081893","type":"journal-article","created":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T14:51:46Z","timestamp":1755183106000},"page":"1893","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Climate Change-Related Temperature Impact on Human Health Risks of Vibrio Species in Bathing and Surface Water"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-9876-0755","authenticated-orcid":false,"given":"Franciska M.","family":"Schets","sequence":"first","affiliation":[{"name":"Centre for Zoonoses and Environmental Microbiology, National Institute for Public Health and the Environment, P.O. Box 1, 3720 BA Bilthoven, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene E.","family":"Pol-Hofstad","sequence":"additional","affiliation":[{"name":"Centre for Zoonoses and Environmental Microbiology, National Institute for Public Health and the Environment, P.O. Box 1, 3720 BA Bilthoven, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7537-9567","authenticated-orcid":false,"given":"Harold H. J. L.","family":"van den Berg","sequence":"additional","affiliation":[{"name":"Centre for Zoonoses and Environmental Microbiology, National Institute for Public Health and the Environment, P.O. Box 1, 3720 BA Bilthoven, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9327-1584","authenticated-orcid":false,"given":"Jack F.","family":"Schijven","sequence":"additional","affiliation":[{"name":"Centre for Zoonoses and Environmental Microbiology, National Institute for Public Health and the Environment, P.O. Box 1, 3720 BA Bilthoven, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,8,14]]},"reference":[{"key":"ref_1","first-page":"8","article-title":"Vibrio spp. infections","volume":"4","author":"Oliver","year":"2018","journal-title":"Nat. Rev. Dis. Primers"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"e0030723","DOI":"10.1128\/aem.00307-23","article-title":"Environmental factors influencing occurrence of Vibrio parahaemolyticus and Vibrio vulnificus","volume":"89","author":"Brumfield","year":"2023","journal-title":"Appl. Environ. Microbiol"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"7314","DOI":"10.1111\/1462-2920.15716","article-title":"Environmental parameters associated with incidence and transmission of pathogenic Vibrio spp.","volume":"23","author":"Brumfield","year":"2021","journal-title":"Environ. Microbiol."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Gangwar, M., Usmani, M., Jamal, Y., Brumfield, K.D., Huq, A., Unnikrishnan, A., Colwell, R.R., and Jutla, A.S. (2023). Environmental factors associated with incidence and distribution of V. parahaemolyticus and V. vulnificus in Chesapeake Bay, Maryland, USA: A three-year case study. bioRxiv.","DOI":"10.1101\/2023.09.25.559351"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"105828","DOI":"10.1016\/j.marenvres.2022.105828","article-title":"Optimum environmental conditions controlling prevalence of Vibrio parahaemolyticus in marine environment","volume":"183","author":"Namadi","year":"2023","journal-title":"Mar. Environ. Res."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"e0268023","DOI":"10.1128\/spectrum.02680-23","article-title":"Vibrio alginolyticus growth kinetics and the metabolic effects of iron","volume":"11","author":"Norfolk","year":"2023","journal-title":"Microbiol. Spectr."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.1099\/mic.0.2006\/005173-0","article-title":"Growth of Vibrio cholerae O1 Ogawa Eltor in freshwater","volume":"153","author":"Vital","year":"2007","journal-title":"Microbiology"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.1128\/AEM.01739-07","article-title":"Rapid growth of planktonic Vibrio cholerae non-O1\/non-O139 strains in a large alkaline lake in Austria: Dependence on temperature and dissolved organic carbon quality","volume":"74","author":"Kirschner","year":"2008","journal-title":"Appl. Environ. Microbiol."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Percival, S.L., Yates, M.V., Williams, D.W., Chalmers, R.M., and Gray, N.F. (2014). Vibrio. Microbiology of Waterborne Diseases\u2014Microbiological Aspects and Risks, Academic Press. [2nd ed.].","DOI":"10.1016\/B978-0-12-415846-7.00012-3"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1086\/375600","article-title":"Cholera and other types of vibriosis: A story of human pandemics and oysters on the half shell","volume":"37","author":"Morris","year":"2003","journal-title":"Clin. Infect. Dis."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.vetmic.2009.03.015","article-title":"Vibrios as causal agents of zoonoses","volume":"140","author":"Austin","year":"2010","journal-title":"Vet. Microbiol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"E5062","DOI":"10.1073\/pnas.1609157113","article-title":"Climate influence on Vibrio and associated human diseases during the past half-century in the coastal North Atlantic","volume":"113","author":"Vezzulli","year":"2016","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.tim.2016.09.008","article-title":"Non-Cholera Vibrios: The microbial barometer of climate change","volume":"25","author":"Trinanes","year":"2017","journal-title":"Trends Microbiol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"3893","DOI":"10.1038\/s41598-023-28247-2","article-title":"Climate warming and increasing Vibrio vulnificus infections in North America","volume":"13","author":"Archer","year":"2023","journal-title":"Sci. Rep."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1038\/nclimate1628","article-title":"Emerging Vibrio risk at high latitudes in response to ocean warming","volume":"3","author":"Trinanes","year":"2013","journal-title":"Nat. Clim. Change"},{"key":"ref_16","first-page":"830","article-title":"The emergence of Vibrio pathogens in Europe: Ecology, evolution, and pathogenesis (Paris, 11\u201312th March 2015)","volume":"6","author":"Wegner","year":"2015","journal-title":"Front. Microbiol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"2002041","DOI":"10.2807\/1560-7917.ES.2021.26.41.2002041","article-title":"Heatwave-associated Vibrio infections in Germany, 2018 and 2019","volume":"26","author":"Brehm","year":"2021","journal-title":"Euro Surveill."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"2101088","DOI":"10.2807\/1560-7917.ES.2022.27.28.2101088","article-title":"Epidemiological and microbiological investigation of a large increase in vibriosis, northern Europe, 2018","volume":"27","author":"Amato","year":"2022","journal-title":"Euro Surveill."},{"key":"ref_19","first-page":"2400075","article-title":"Epidemiological and environmental investigation of the \u2018big four\u2019 Vibrio species, 1994 to 2021: A Baltic Sea retrospective study","volume":"29","author":"Kube","year":"2024","journal-title":"Euro Surveill."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.fm.2017.09.011","article-title":"Seafood pathogens and information on antimicrobial resistance: A review","volume":"70","author":"Elbashir","year":"2018","journal-title":"Food Microbiol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1007\/s00248-011-9990-9","article-title":"Seasonal dynamics and modeling of a Vibrio community in coastal waters of the North Sea","volume":"63","author":"Oberbeckmann","year":"2012","journal-title":"Microb. Ecol."},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Vezzulli, L., Pezzati, E., Brettar, I., H\u00f6fle, M., and Pruzzo, C. (2015). Effects of global warming on Vibrio ecology. Microbiol. Spec., 3.","DOI":"10.1128\/microbiolspec.VE-0004-2014"},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Almuhaideb, E., Chintapenta, L.K., Abbott, A., Parveen, S., and Ozbay, G. (2020). Assessment of Vibrio parahaemolyticus levels in oysters (Crassostrea virginica) and seawater in Delaware Bay in relation to environmental conditions and the prevalence of molecular markers to identify pathogenic Vibrio parahaemolyticus strains. PLoS ONE, 15.","DOI":"10.1371\/journal.pone.0242229"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/S1473-3099(09)70104-5","article-title":"Climate change and infectious diseases in Europe","volume":"9","author":"Semenza","year":"2009","journal-title":"Lancet Infect. Dis."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"e243","DOI":"10.1017\/S0950268819001316","article-title":"Effects of large-scale oceanic phenomena on non-cholera vibriosis incidence in the United States: Implications for climate change","volume":"147","author":"Ling","year":"2019","journal-title":"Epidemiol. Infect."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"4101","DOI":"10.1111\/1462-2920.14967","article-title":"In hot water: Effect of climate change on Vibrio-human interactions","volume":"22","author":"Froelich","year":"2020","journal-title":"Environ. Microbiol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1111\/1462-2920.13955","article-title":"Vibrio vulnificus: New insights into a deadly opportunistic pathogen","volume":"20","author":"Oliver","year":"2018","journal-title":"Environ. Microbiol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.ijheh.2011.05.003","article-title":"Potentially human pathogenic vibrios in marine and fresh bathing waters related to environmental conditions and disease outcome","volume":"214","author":"Schets","year":"2011","journal-title":"Int. J. Hyg. Environ. Health"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1111\/risa.12365","article-title":"Effect of climate change on the concentration and associated risks of Vibrio spp. in Dutch recreational waters","volume":"35","author":"Sterk","year":"2015","journal-title":"Risk Anal."},{"key":"ref_30","unstructured":"Van den Hurk, B., Siegmund, P., Klein Tank, A., Attema, J., Bakker, A., Beersma, J., Bessembinder, J., Boers, R., Brandsma, T., and van den Brink, H. (2025, July 01). KNMI\u201914: Climate Change Scenarios for the 21st Century\u2014A Netherlands Perspective, 2014, KNMI Number: WR-2014-01. Available online: https:\/\/cdn.knmi.nl\/knmi\/pdf\/bibliotheek\/knmipubWR\/WR2014-01.pdf."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"136113","DOI":"10.1016\/j.scitotenv.2019.136113","article-title":"Potentially human pathogenic Vibrio spp. in a coastal transect: Occurrence and multiple virulence factors","volume":"707","author":"Hackbusch","year":"2020","journal-title":"Sci. Total Environ."},{"key":"ref_32","doi-asserted-by":"crossref","unstructured":"Sacheli, R., Philippe, C., Meex, C., Mzougui, S., Melin, P., and Hayette, M. (2023). Occurrence of Vibrio spp. in selected recreational water bodies in Belgium during 2021 bathing season. Int. J. Environ. Res. Public Health, 20.","DOI":"10.3390\/ijerph20206932"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"110570","DOI":"10.1016\/j.marpolbul.2019.110570","article-title":"Enteric viruses, somatic coliphages and Vibrio species in marine bathing and non-bathing waters in Italy","volume":"149","author":"Bonadonna","year":"2019","journal-title":"Mar. Pollut. Bull."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1111\/1758-2229.13136","article-title":"First report on the occurrence of Vibrio cholerae nonO1\/nonO139 in natural and artificial lakes and ponds in Serbia: Evidence for a long-distance transfer of strains and the presence of Vibrio paracholerae","volume":"15","author":"Rehm","year":"2023","journal-title":"Environ. Microbiol. Rep."},{"key":"ref_35","unstructured":"Van Dorland, R., Beersma, J., Bessembinder, J., Bloemendaal, N., van den Brink, H., Brotons Blanes, M., Drijfhout, S., Haarsma, R., Keizer, I., and Krikken, F. (2025, July 01). KNMI National Climate Scenarios 2023 for the Netherlands, 2023, KNMI Number: WR-23-02. Available online: https:\/\/cdn.knmi.nl\/system\/data_center_publications\/files\/000\/071\/902\/original\/KNMI23_climate_scenarios_scientific_report_WR23-02.pdf?1710489430."},{"key":"ref_36","unstructured":"(2006). Water Quality\u2014Sampling for Microbiological Analysis (Standard No. ISO 19458)."},{"key":"ref_37","unstructured":"(2017). Microbiology of the Food Chain\u2014Horizontal Method for the Determination of Vibrio spp. Part 1: Detection of Potentially Enteropathogenic Vibrio parahaemolyticus, Vibrio cholerae and Vibrio vulnificus (Standard No. ISO 21872-1)."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1111\/j.1574-695X.2005.00016.x","article-title":"Application of real-time PCR for quantitative detection of Vibrio parahaemolyticus from seafood in eastern China","volume":"46","author":"Cai","year":"2006","journal-title":"FEMS Immunol. Med. Microbiol."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"5702","DOI":"10.1128\/AEM.71.10.5702-5709.2005","article-title":"Real-time PCR detection of Vibrio vulnificus in oysters: Comparison of oligonucleotide primers and probes targeting vvhA","volume":"71","author":"Panicker","year":"2005","journal-title":"Appl. Environ. Microbiol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18637\/jss.v082.i13","article-title":"lmerTest Package: Tests in Linear Mixed Effects Models","volume":"82","author":"Kuznetsova","year":"2017","journal-title":"J. Stat. Softw."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1111\/j.1539-6924.1999.tb01143.x","article-title":"Dose response models for infectious gastroenteritis","volume":"19","author":"Teunis","year":"1999","journal-title":"Risk Anal."},{"key":"ref_42","unstructured":"FDA (2025, July 01). Quantitative Risk Assessment on the Public Health Impact of Pathogenic Vibrio parahaemolyticus in Raw Oysters, Available online: https:\/\/www.fda.gov\/food\/risk-and-safety-assessments-food\/quantitative-risk-assessment-public-health-impact-pathogenic-vibrio-parahaemolyticus-raw-oysters."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.foodcont.2017.10.022","article-title":"The risk of Vibrio parahaemolyticus infections associated with consumption of raw oysters as affected by processing and distribution conditions in Taiwan","volume":"86","author":"Huang","year":"2018","journal-title":"Food Control"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"2392","DOI":"10.1016\/j.watres.2011.01.025","article-title":"Exposure assessment for swimmers in bathing waters and swimming pools","volume":"45","author":"Schets","year":"2011","journal-title":"Water Res."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1007\/s00248-013-0221-4","article-title":"Temporal and spatial distribution patterns of potentially pathogenic Vibrio spp. at recreational beaches of the German north sea","volume":"65","author":"Heinemeyer","year":"2013","journal-title":"Microb. Ecol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"846819","DOI":"10.3389\/fcimb.2022.846819","article-title":"Prevalence and distribution of potentially human pathogenic Vibrio spp. on German North and Baltic Sea coasts","volume":"12","author":"Fleischmann","year":"2022","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"38","DOI":"10.3389\/fmicb.2014.00038","article-title":"Associations and dynamics of Vibrionaceae in the environment, from the genus to the population level","volume":"5","author":"Takemura","year":"2014","journal-title":"Front. Microbiol."},{"key":"ref_48","unstructured":"Ministerie van Infrastructuur en Waterstaat, Inspectie Leefomgeving en Transport (2020). Richtsnoer Analyse Microbiologische Veiligheid Drinkwater (AMVD), Inspectie Leefomgeving en Transport (ILT). (In Dutch)."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1046\/j.1469-0691.2001.00207.x","article-title":"Vibrio alginolyticus acute gastroenteritis: Report of two cases","volume":"7","author":"Uh","year":"2001","journal-title":"Clin. Microbiol. Infect."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"19994","DOI":"10.2807\/ese.16.42.19994-en","article-title":"Vibrio alginolyticus-associated wound infection acquired in British waters, Guernsey, July 2011","volume":"16","author":"Reilly","year":"2011","journal-title":"Euro Surveill."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1017\/S0950268817000140","article-title":"Vibrio alginolyticus infections in the USA, 1988\u20132012","volume":"145","author":"Newton","year":"2017","journal-title":"Epidemiol. Infect."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"2367","DOI":"10.3201\/eid2812.220748","article-title":"Clinical and epidemiologic characteristics and therapeutic management of patients with Vibrio infections, Bay of Biscay, France, 2001\u20132019","volume":"28","author":"Hoefler","year":"2022","journal-title":"Emerg. Infect. Dis."},{"key":"ref_53","unstructured":"Schets, F.M., Pol-Hofstad, I.E., van den Berg, H.H.J.L., Lynch, G., Serafim, F., van Overbeek, W.M., and Schijven, J.F. (2023). Risico\u2019s van Vibrio-Besmetting in Zwemwater, Schelpdierproductiewater en Schelpdieren, Rijksinstituut voor Volksgezondheid en Milieu. (In Dutch)."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"2289","DOI":"10.1007\/s12237-018-0424-5","article-title":"Impact of Climate Change on Vibrio vulnificus abundance and exposure risk","volume":"41","author":"Deeb","year":"2018","journal-title":"Estuaries Coasts"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"e426","DOI":"10.1016\/S2542-5196(21)00169-8","article-title":"Future scenarios of risk of Vibrio infections in a warming planet: A global mapping study","volume":"5","author":"Trinanes","year":"2021","journal-title":"Lancet Planet. Health"},{"key":"ref_56","unstructured":"Intergovernmental Panel on Climate Change (IPCC) (2025, July 01). Climate Change 2021: The Physical Science Basis. Available online: https:\/\/www.ipcc.ch\/report\/ar6\/wg1\/."}],"container-title":["Microorganisms"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-2607\/13\/8\/1893\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T18:27:15Z","timestamp":1760034435000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-2607\/13\/8\/1893"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,14]]},"references-count":56,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2025,8]]}},"alternative-id":["microorganisms13081893"],"URL":"https:\/\/doi.org\/10.3390\/microorganisms13081893","relation":{},"ISSN":["2076-2607"],"issn-type":[{"value":"2076-2607","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,14]]}}}