{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T06:07:03Z","timestamp":1770962823539,"version":"3.50.1"},"reference-count":121,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:00:00Z","timestamp":1770768000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microorganisms"],"abstract":"<jats:p>Antimicrobial resistance constitutes a major global public health challenge, with Romania among the European countries affected. Acinetobacter baumannii and Pseudomonas aeruginosa was designated by the World Health Organization (WHO) as priority pathogens, are frequently implicated in healthcare-associated infections (HAIs), including pneumonia, surgical site infections, urinary tract infections, and bacteremia. We have narratively synthesized surveillance studies published in different regions of Romania, encompassing date whit the period 2001\u20132024. A total of 13 studies reporting data on P. aeruginosa (2003\u20132024) and 15 studies on A. baumannii (2001\u20132024) were included. The strains were isolated from various pathological products, including urine, sputum, tracheobronchial aspirate, blood, bronchoalveolar lavage, pus, peritoneal fluid, and cerebrospinal fluid, from hospitalized patients in different clinical departments. This review evaluated long-term trends in antimicrobial resistance profiles of A. baumannii and P. aeruginosa strains circulating in various regions of Romania. The findings revealed both temporal variability in resistance rates within comparable intervals and differences across distinct time periods. These long-term trends underscore the need for sustained national surveillance systems, harmonized reporting practices, and reinforced antimicrobial stewardship programs.<\/jats:p>","DOI":"10.3390\/microorganisms14020429","type":"journal-article","created":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T17:45:36Z","timestamp":1770831936000},"page":"429","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Evolution of Antimicrobial Resistance in Acinetobacter baumannii and Pseudomonas aeruginosa in Romania: A Narrative Review of Published Data (2001\u20132024)"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0126-0640","authenticated-orcid":false,"given":"Elena Roxana","family":"Buzil\u0103","sequence":"first","affiliation":[{"name":"Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Ia\u0219i, Romania"},{"name":"National Institute of Public Health, Iasi Regional Center for Public Health, 700465 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7720-4499","authenticated-orcid":false,"given":"Olivia Simona","family":"Dorneanu","sequence":"additional","affiliation":[{"name":"Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Ia\u0219i, Romania"},{"name":"Clinical Hospital of Infectious Diseases \u201cSf. Parascheva\u201d, 700116 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2592-3982","authenticated-orcid":false,"given":"Lumini\u021ba Smaranda","family":"Iancu","sequence":"additional","affiliation":[{"name":"Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Ia\u0219i, Romania"},{"name":"National Institute of Public Health, Iasi Regional Center for Public Health, 700465 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8551-3053","authenticated-orcid":false,"given":"Felicia","family":"Trofin","sequence":"additional","affiliation":[{"name":"Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Ia\u0219i, Romania"},{"name":"\u201cSf. Spiridon\u201d Clinical Emergency Hospital, 700111 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6076-7818","authenticated-orcid":false,"given":"Alexandru","family":"Duhaniuc","sequence":"additional","affiliation":[{"name":"Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Ia\u0219i, Romania"},{"name":"National Institute of Public Health, Iasi Regional Center for Public Health, 700465 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1510-3398","authenticated-orcid":false,"given":"Costin","family":"Damian","sequence":"additional","affiliation":[{"name":"Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Ia\u0219i, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7746-2383","authenticated-orcid":false,"given":"C\u0103t\u0103lina","family":"Lunc\u0103","sequence":"additional","affiliation":[{"name":"Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115 Ia\u0219i, Romania"},{"name":"Emergency Clinical Hospital for Children \u201cSf. Maria\u201d, 700309 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,2,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e00088-17","DOI":"10.1128\/CMR.00088-17","article-title":"Mobile Genetic Elements Associated with Antimicrobial Resistance","volume":"31","author":"Partridge","year":"2018","journal-title":"Clin. Microbiol. Rev."},{"key":"ref_2","unstructured":"World Health Organization (WHO) (2025, September 10). Global Antimicrobial Resistance Surveillance System (GLASS) Report: Early Implementation 2017\u20132018. Available online: https:\/\/www.who.int\/publications\/i\/item\/9789241515061."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Balea, L.B., and Glasdam, S. (2024). 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