{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T12:31:51Z","timestamp":1787056311162,"version":"build-2736575974"},"reference-count":59,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:00:00Z","timestamp":1786492800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"crossref","award":["5R25HL105446-11"],"award-info":[{"award-number":["5R25HL105446-11"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"crossref"}]},{"award":["5R25HL105446-11"],"award-info":[{"award-number":["5R25HL105446-11"]}],"id":[{"id":"https:\/\/ror.org\/012pb6c26","id-type":"ROR","asserted-by":"publisher"}]},{"name":"SUNY Downstate Health Sciences University"},{"id":[{"id":"https:\/\/ror.org\/0041qmd21","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microorganisms"],"abstract":"<jats:p>Carotenoids are bioactive compounds abundant in fruits and vegetables that may influence gut microbial composition through effects on the intestinal environment; however, evidence in emerging adults remains limited. This pilot study examined associations between carotenoid intake and gut microbial composition through a cross-sectional analysis of 50 Latino emerging adults (18\u201325 years). Dietary intake was assessed using three 24 h recalls, and carotenoid intake was modeled continuously and by tertiles. Microbial profiling was conducted using 16S rRNA gene sequencing (V3\u2013V4 region) from stool samples. \u03b1-Diversity was analyzed using multivariable linear regression and \u03b2-diversity using PERMANOVA (9999 permutations), adjusting for relevant covariates. Participants were 20.3 \u00b1 2.19 years old and 74.0% female. Continuous carotenoid intake was not associated with \u03b1- or \u03b2-diversity. A nominal association was observed between higher carotenoid intake tertiles and greater Chao1 richness (B = 7.06; 95% CI: 0.40, 13.7; p = 0.038); however, this association did not remain statistically significant after Benjamini\u2013Hochberg false discovery rate correction. In sensitivity analyses additionally adjusted for dietary fiber and fruit and vegetable intake, carotenoid tertiles were associated with unweighted UniFrac (R2 = 0.08; p = 0.009). Exploratory differential abundance analyses identified taxa that varied across intake groups. Although carotenoid intake was not associated with global microbial diversity, exploratory differences in richness and taxonomic composition were observed across intake levels, suggesting that carotenoids may be associated with specific features of gut microbial community structure in Latino emerging adults. These preliminary findings from this pilot study warrant confirmation in larger studies.<\/jats:p>","DOI":"10.3390\/microorganisms14081775","type":"journal-article","created":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T11:02:11Z","timestamp":1786532531000},"page":"1775","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Dietary Carotenoid Intake, Gut Microbial Diversity, and Community Composition in Latino Emerging Adults"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-1461-7912","authenticated-orcid":false,"given":"Alexandra","family":"Briceno","sequence":"first","affiliation":[{"name":"Department of Dietetics and Nutrition, Robert Stempel College of Public Health & Social Work, Florida International University, Miami, FL 33199, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9437-0376","authenticated-orcid":false,"given":"Cristina","family":"Palacios","sequence":"additional","affiliation":[{"name":"Department of Dietetics and Nutrition, Robert Stempel College of Public Health & Social Work, Florida International University, Miami, FL 33199, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijaya","family":"Narayanan","sequence":"additional","affiliation":[{"name":"Department of Dietetics and Nutrition, Robert Stempel College of Public Health & Social Work, Florida International University, Miami, FL 33199, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4901-963X","authenticated-orcid":false,"given":"Florence","family":"George","sequence":"additional","affiliation":[{"name":"Department of Mathematics and Statistics, Florida International University, Miami, FL 33199, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0158-8104","authenticated-orcid":false,"given":"Sabrina","family":"Sales Martinez","sequence":"additional","affiliation":[{"name":"Department of Dietetics and Nutrition, Robert Stempel College of Public Health & Social Work, Florida International University, Miami, FL 33199, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,8,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/j.molmed.2023.07.002","article-title":"The global human gut microbiome: Genes, lifestyles, and diet","volume":"29","author":"Parizadeh","year":"2023","journal-title":"Trends Mol. Med."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1007\/s10620-020-06112-w","article-title":"Diet and the human gut microbiome: An international review","volume":"65","author":"Wilson","year":"2020","journal-title":"Dig. Dis. Sci."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1126\/science.1208344","article-title":"Linking long-term dietary patterns with gut microbial enterotypes","volume":"334","author":"Wu","year":"2011","journal-title":"Science"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1038\/nature12506","article-title":"Richness of human gut microbiome correlates with metabolic markers","volume":"500","author":"Nielsen","year":"2013","journal-title":"Nature"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1600252","DOI":"10.1002\/mnfr.201600252","article-title":"Gut microbiota, diet, and obesity-related disorders\u2014The good, the bad, and the future challenges","volume":"61","author":"Portune","year":"2017","journal-title":"Mol. Nutr. Food Res."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.lfs.2018.10.063","article-title":"Interaction between gut microbiome and cardiovascular disease","volume":"214","author":"Peng","year":"2018","journal-title":"Life Sci."},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Rocha, H.R., Coelho, M.C., Gomes, A.M., and Pintado, M.E. (2023). Carotenoids diet: Digestion, gut microbiota modulation, and inflammatory diseases. Nutrients, 15.","DOI":"10.3390\/nu15102265"},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Puhlmann, M.L., and de Vos, W.M. (2022). Intrinsic dietary fibers and the gut microbiome: Rediscovering the benefits of the plant cell matrix for human health. Front. Immunol., 13.","DOI":"10.3389\/fimmu.2022.954845"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s12937-025-01079-8","article-title":"Dietary carotenoid intakes and biological aging among US adults, NHANES 1999\u20132018","volume":"24","author":"Qi","year":"2025","journal-title":"Nutr. J."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"8715","DOI":"10.1002\/fsn3.4502","article-title":"Nutritional benefits of lycopene and beta-carotene: A comprehensive overview","volume":"12","author":"Tufail","year":"2024","journal-title":"Food Sci. Nutr."},{"key":"ref_11","first-page":"100834","article-title":"Carotenoids: Dietary sources, health functions, biofortification, marketing trend and affecting factors: A review","volume":"14","author":"Gebregziabher","year":"2023","journal-title":"J. Agric. Food Res."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1093\/nutrit\/nuaa008","article-title":"From carotenoid intake to carotenoid blood and tissue concentrations\u2014Implications for dietary intake recommendations","volume":"79","author":"Lietz","year":"2021","journal-title":"Nutr. Rev."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/S0889-1575(03)00025-5","article-title":"Dietary reference intakes: Revised nutritional equivalents for folate, vitamin E and provitamin A carotenoids","volume":"16","author":"Trumbo","year":"2003","journal-title":"J. Food Compos. Anal."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1079\/BJN2000284","article-title":"A European carotenoid database to assess carotenoid intakes and its use in a five-country comparative study","volume":"85","author":"Carroll","year":"2001","journal-title":"Br. J. Nutr."},{"key":"ref_15","unstructured":"Institute of Medicine (2000). Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids, National Academies Press."},{"key":"ref_16","unstructured":"Institute of Medicine (2001). Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc, National Academies Press."},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Zia-Ul-Haq, M., Dewanjee, S., and Riaz, M. (2021). Carotenoids as antioxidants. Carotenoids: Structure and Function in the Human Body, Springer.","DOI":"10.1007\/978-3-030-46459-2"},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Kim, K., Madore, M.P., and Chun, O.K. (2023). Changes in intake and major food sources of carotenoids among U.S. adults between 2009\u20132018. Metabolites, 14.","DOI":"10.3390\/metabo14010013"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.advnut.2022.10.007","article-title":"Carotenoids and their health benefits as derived via their interactions with gut microbiota","volume":"14","author":"Eroglu","year":"2023","journal-title":"Adv. Nutr."},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Mosca, L., Pagano, C., Tafuri, M.G., Di Maio, G., Rejano-Gordillo, C.M., Della Marca, R., D\u2019Angelo, S., Monda, M., Messina, G., and Polito, R. (2026). The Gut Microbiota\u2013Polyphenol\u2013NLR3 Inflammasome Axis: A Key Regulatory Network Linking Diet to Chronic Inflammation. Nutrients, 18.","DOI":"10.3390\/nu18101483"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.nutres.2021.09.001","article-title":"Vitamins, the gut microbiome and gastrointestinal health in humans","volume":"95","author":"Pham","year":"2021","journal-title":"Nutr. Res."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1111\/1750-3841.15586","article-title":"Dietary and plasma carotenoids are positively associated with alpha diversity in the fecal microbiota of pregnant women","volume":"86","author":"Schmidt","year":"2021","journal-title":"J. Food Sci."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.jand.2021.05.023","article-title":"The gut microbiome is associated with circulating dietary biomarkers of fruit and vegetable intake in a multiethnic cohort","volume":"122","author":"Frankenfeld","year":"2022","journal-title":"J. Acad. Nutr. Diet."},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Valdes, A.M., Louca, P., Visconti, A., Asnicar, F., Bermingham, K., Nogal, A., Wong, K., Michelotti, G.A., Wolf, J., and Segata, N. (2024). Vitamin A carotenoids, but not retinoids, mediate the impact of a healthy diet on gut microbial diversity. BMC Med., 22.","DOI":"10.1186\/s12916-024-03543-4"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"4625279","DOI":"10.1155\/2019\/4625279","article-title":"Prebiotic effect of lycopene and dark chocolate on gut microbiome with systemic changes in liver metabolism, skeletal muscles and skin in moderately obese persons","volume":"2019","author":"Wiese","year":"2019","journal-title":"BioMed Res. Int."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1002\/ptr.5009","article-title":"Evaluation of the effect of blackcurrant products on gut microbiota and on markers of risk for colon cancer in humans","volume":"28","author":"Molan","year":"2014","journal-title":"Phytother. Res."},{"key":"ref_27","doi-asserted-by":"crossref","unstructured":"Hochberg, Z., and Konner, M. (2020). Emerging adulthood, a pre-adult life-history stage. Front. Endocrinol., 10.","DOI":"10.3389\/fendo.2019.00918"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.socscimed.2017.09.041","article-title":"Health lifestyles across the transition to adulthood: Implications for health","volume":"193","author":"Lawrence","year":"2017","journal-title":"Soc. Sci. Med."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1186\/s13059-019-1831-z","article-title":"Gut microbiome composition in the Hispanic Community Health Study\/Study of Latinos is shaped by geographic relocation, environmental factors, and obesity","volume":"20","author":"Kaplan","year":"2019","journal-title":"Genome Biol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1186\/s40814-025-01675-9","article-title":"Sample size justification in feasibility studies: Moving beyond published guidance","volume":"11","author":"Montgomery","year":"2025","journal-title":"Pilot Feasibility Stud."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1111\/j..2002.384.doc.x","article-title":"Design and analysis of pilot studies: Recommendations for good practice","volume":"10","author":"Lancaster","year":"2004","journal-title":"J. Eval. Clin. Pract."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1249\/01.MSS.0000078924.61453.FB","article-title":"International physical activity questionnaire: 12-country reliability and validity","volume":"35","author":"Craig","year":"2003","journal-title":"Med. Sci. Sports Exerc."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1016\/j.jand.2012.04.016","article-title":"The Automated Self-Administered 24-Hour Dietary Recall (ASA24): A resource for researchers, clinicians, and educators from the National Cancer Institute","volume":"112","author":"Subar","year":"2012","journal-title":"J. Acad. Nutr. Diet."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1016\/j.jand.2018.05.020","article-title":"Applications of the Healthy Eating Index for surveillance, epidemiology, and intervention research: Considerations and caveats","volume":"118","author":"Kirkpatrick","year":"2018","journal-title":"J. Acad. Nutr. Diet."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1016\/j.jand.2018.05.021","article-title":"Update of the Healthy Eating Index: HEI-2015","volume":"118","author":"Pannucci","year":"2018","journal-title":"J. Acad. Nutr. Diet."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1016\/j.jand.2023.05.015","article-title":"Healthy Eating Index-2020: Review and update process to reflect the Dietary Guidelines for Americans, 2020-2025","volume":"123","author":"Pannucci","year":"2023","journal-title":"J. Acad. Nutr. Diet."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"R60","DOI":"10.1186\/gb-2011-12-6-r60","article-title":"Metagenomic biomarker discovery and explanation","volume":"12","author":"Segata","year":"2011","journal-title":"Genome Biol."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/j.jand.2017.09.013","article-title":"Colonic mucosal bacteria are associated with inter-individual variability in serum carotenoid concentrations","volume":"118","author":"Djuric","year":"2018","journal-title":"J. Acad. Nutr. Diet."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"284","DOI":"10.3945\/jn.110.129684","article-title":"Neighborhood socioeconomic status is associated with serum carotenoid concentrations in older, community-dwelling women","volume":"141","author":"Nicklett","year":"2011","journal-title":"J. Nutr."},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"Lv, J., Xu, T., Lou, S., Zhan, Z., Cheng, Z., and Fu, F. (2024). Association between serum \u03b2-carotene and suicidal ideation in adults: A cross-sectional study. Front. Nutr., 11.","DOI":"10.3389\/fnut.2024.1500107"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1111\/joim.20089","article-title":"Gut microbiota development across the lifespan: Disease links and health-promoting interventions","volume":"297","author":"Schoultz","year":"2025","journal-title":"J. Intern. Med."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1038\/nature11053","article-title":"Human gut microbiome viewed across age and geography","volume":"486","author":"Yatsunenko","year":"2012","journal-title":"Nature"},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"Gyriki, D., Nikolaidis, C.G., Bezirtzoglou, E., Voidarou, C., Stavropoulou, E., and Tsigalou, C. (2025). The gut microbiota and aging: Interactions, implications, and interventions. Front. Aging, 6.","DOI":"10.3389\/fragi.2025.1452917"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"4586","DOI":"10.1073\/pnas.1000097107","article-title":"Composition, variability, and temporal stability of the intestinal microbiota of the elderly","volume":"108","author":"Claesson","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"Kers, J.G., and Saccenti, E. (2022). The power of microbiome studies: Some considerations on which alpha and beta metrics to use and how to report results. Front. Microbiol., 12.","DOI":"10.3389\/fmicb.2021.796025"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1046\/j.1461-0248.2001.00230.x","article-title":"Quantifying biodiversity: Procedures and pitfalls in the measurement and comparison of species richness","volume":"4","author":"Gotelli","year":"2001","journal-title":"Ecol. Lett."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.1128\/AEM.01996-06","article-title":"Quantitative and qualitative \u03b2 diversity measures lead to different insights into factors that structure microbial communities","volume":"73","author":"Lozupone","year":"2007","journal-title":"Appl. Environ. Microbiol."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1016\/j.jand.2018.05.019","article-title":"Evaluation of the Healthy Eating Index-2015","volume":"118","author":"Reedy","year":"2018","journal-title":"J. Acad. Nutr. Diet."},{"key":"ref_49","doi-asserted-by":"crossref","unstructured":"Colby, S., Zhou, W., Allison, C., Mathews, A.E., Olfert, M.D., Morrell, J.S., Byrd-Bredbenner, C., Greene, G., Brown, O., and Kattelmann, K. (2020). Development and validation of the short Healthy Eating Index survey with a college population to assess dietary quality and intake. Nutrients, 12.","DOI":"10.3390\/nu12092611"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1007\/s40495-019-00196-3","article-title":"Gut Microbiota, Dietary Phytochemicals, and Benefits to Human Health","volume":"5","author":"Yin","year":"2019","journal-title":"Curr. Pharmacol. Rep."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"vvae008","DOI":"10.1093\/ijfood\/vvae008","article-title":"From diet to microbiota: How fruits and vegetables influence gut microbiota","volume":"60","author":"Jia","year":"2025","journal-title":"Int. J. Food Sci. Technol."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1038\/nature25973","article-title":"Environment dominates over host genetics in shaping human gut microbiota","volume":"555","author":"Rothschild","year":"2018","journal-title":"Nature"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1038\/ismej.2010.133","article-title":"UniFrac: An effective distance metric for microbial community comparison","volume":"5","author":"Lozupone","year":"2011","journal-title":"ISME J."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"8228","DOI":"10.1128\/AEM.71.12.8228-8235.2005","article-title":"UniFrac: A new phylogenetic method for comparing microbial communities","volume":"71","author":"Lozupone","year":"2005","journal-title":"Appl. Environ. Microbiol."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"100137","DOI":"10.1016\/j.medmic.2025.100137","article-title":"The metabolic and immunomodulatory functions of Bacteroides fragilis; a next-generation probiotic?","volume":"25","author":"Roustapoor","year":"2025","journal-title":"Med. Microecol."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/19490976.2021.1897212","article-title":"The role of short-chain fatty acids in the interplay between gut microbiota and diet in cardio-metabolic health","volume":"13","author":"Nogal","year":"2021","journal-title":"Gut Microbes"},{"key":"ref_57","doi-asserted-by":"crossref","unstructured":"Gerasimidis, K., Nichols, B., McGowan, M., Svolos, V., Papadopoulou, R., Kokkorou, M., Rebull, M., Gonzalez, T.B., Hansen, R., and Russell, R.K. (2022). The effects of commonly consumed dietary fibres on the gut microbiome and its fibre fermentative capacity in adults with inflammatory bowel disease in remission. Nutrients, 14.","DOI":"10.3390\/nu14051053"},{"key":"ref_58","doi-asserted-by":"crossref","unstructured":"Hodge, A., Cunningham, J., Maple-Brown, L., Dunbar, T., and O\u2019Dea, K. (2011). Plasma carotenoids are associated with socioeconomic status in an urban Indigenous population: An observational study. BMC Public Health, 11.","DOI":"10.1186\/1471-2458-11-76"},{"key":"ref_59","doi-asserted-by":"crossref","unstructured":"Johnson, A.J., Zheng, J.J., Kang, J.W., Saboe, A., Knights, D., and Zivkovic, A.M. (2020). A guide to diet-microbiome study design. Front. Nutr., 7.","DOI":"10.3389\/fnut.2020.00079"}],"container-title":["Microorganisms"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2076-2607\/14\/8\/1775\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T12:19:02Z","timestamp":1787055542000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2076-2607\/14\/8\/1775"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,12]]},"references-count":59,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2026,8]]}},"alternative-id":["microorganisms14081775"],"URL":"https:\/\/doi.org\/10.3390\/microorganisms14081775","relation":{},"ISSN":["2076-2607"],"issn-type":[{"value":"2076-2607","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,12]]}}}