{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T04:26:18Z","timestamp":1760243178681,"version":"build-2065373602"},"reference-count":34,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2015,12,2]],"date-time":"2015-12-02T00:00:00Z","timestamp":1449014400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microorganisms"],"abstract":"<jats:p>Select Agents are microorganisms and toxins considered to be exploitable as biological weapons. Although infections by many Select Agents can be treated by conventional antibiotics, the risk of an emerging or engineered drug resistant strain is of great concern. One group of microorganisms that is showing potential to control drug resistant Gram-negative bacteria are the predatory bacteria from the genera  Bdellovibrio spp. and Micavibrio spp. In this study, we have examined the ability of Bdellovibrio bacteriovorus (B. bacteriovorus) strain 109J, HD100 and Micavibrio aeruginosavorus (M. aeruginosavorus) ARL-13 to prey on a variety of Select Agents. Our findings demonstrate that B. bacteriovorus and M. aeruginosavorus are able to prey efficiently on Yersinia pestis and Burkholderia mallei. Modest predation was also measured in co-cultures of B. bacteriovorus and Francisella tularensis. However, neither of the predators showed predation when Burkholderia pseudomallei and Brucella melitensis were used as prey.<\/jats:p>","DOI":"10.3390\/microorganisms3040903","type":"journal-article","created":{"date-parts":[[2015,12,2]],"date-time":"2015-12-02T10:44:27Z","timestamp":1449053067000},"page":"903-912","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Susceptibility of Select Agents to Predation by  Predatory Bacteria"],"prefix":"10.3390","volume":"3","author":[{"given":"Riccardo","family":"Russo","sequence":"first","affiliation":[{"name":"Department of Medicine and the Center for Emerging Pathogens, Rutgers, New Jersey Medical School, Newark, NJ 07101, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Chae","sequence":"additional","affiliation":[{"name":"Department of Oral Biology, Rutgers School of Dental Medicine, Newark, NJ 07101, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Somdatta","family":"Mukherjee","sequence":"additional","affiliation":[{"name":"Department of Oral Biology, Rutgers School of Dental Medicine, Newark, NJ 07101, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Singleton","sequence":"additional","affiliation":[{"name":"Department of Medicine and the Center for Emerging Pathogens, Rutgers, New Jersey Medical School, Newark, NJ 07101, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Occi","sequence":"additional","affiliation":[{"name":"Department of Medicine and the Center for Emerging Pathogens, Rutgers, New Jersey Medical School, Newark, NJ 07101, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Kadouri","sequence":"additional","affiliation":[{"name":"Department of Oral Biology, Rutgers School of Dental Medicine, Newark, NJ 07101, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy","family":"Connell","sequence":"additional","affiliation":[{"name":"Department of Medicine and the Center for Emerging Pathogens, Rutgers, New Jersey Medical School, Newark, NJ 07101, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2015,12,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e63397","DOI":"10.1371\/journal.pone.0063397","article-title":"Predatory bacteria: A potential ally against multidrug-resistant gram-negative pathogens","volume":"8","author":"Kadouri","year":"2013","journal-title":"PLoS ONE"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/BF02046064","article-title":"Bdellovibrio bacteriovorus gen. et sp. n., a predatory, ectoparasitic, and bacteriolytic microorganism","volume":"29","author":"Stolp","year":"1963","journal-title":"Anton. 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