{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T05:49:03Z","timestamp":1780465743787,"version":"3.54.1"},"reference-count":43,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2021,4,2]],"date-time":"2021-04-02T00:00:00Z","timestamp":1617321600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"publisher","award":["INV-010429 \/ OPP1189065"],"award-info":[{"award-number":["INV-010429 \/ OPP1189065"]}],"id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microorganisms"],"abstract":"<jats:p>Serotype-specific surveillance for invasive pneumococcal disease (IPD) is essential for assessing the impact of 10- and 13-valent pneumococcal conjugate vaccines (PCV10\/13). The Pneumococcal Serotype Replacement and Distribution Estimation (PSERENADE) project aimed to evaluate the global evidence to estimate the impact of PCV10\/13 by age, product, schedule, and syndrome. Here we systematically characterize and summarize the global landscape of routine serotype-specific IPD surveillance in PCV10\/13-using countries and describe the subset that are included in PSERENADE. Of 138 countries using PCV10\/13 as of 2018, we identified 109 with IPD surveillance systems, 76 of which met PSERENADE data collection eligibility criteria. PSERENADE received data from most (n = 63, 82.9%), yielding 240,639 post-PCV10\/13 introduction IPD cases. Pediatric and adult surveillance was represented from all geographic regions but was limited from lower income and high-burden countries. In PSERENADE, 18 sites evaluated PCV10, 42 PCV13, and 17 both; 17 sites used a 3 + 0 schedule, 38 used 2 + 1, 13 used 3 + 1, and 9 used mixed schedules. With such a sizeable and generally representative dataset, PSERENADE will be able to conduct robust analyses to estimate PCV impact and inform policy at national and global levels regarding adult immunization, schedule, and product choice, including for higher valency PCVs on the horizon.<\/jats:p>","DOI":"10.3390\/microorganisms9040742","type":"journal-article","created":{"date-parts":[[2021,4,2]],"date-time":"2021-04-02T04:13:51Z","timestamp":1617336831000},"page":"742","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":53,"title":["Global Landscape Review of Serotype-Specific Invasive Pneumococcal Disease Surveillance among Countries Using PCV10\/13: The Pneumococcal Serotype Replacement and Distribution Estimation (PSERENADE) Project"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9041-2671","authenticated-orcid":false,"given":"Maria","family":"Deloria Knoll","sequence":"first","affiliation":[{"name":"Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2559-2922","authenticated-orcid":false,"given":"Julia","family":"Bennett","sequence":"additional","affiliation":[{"name":"Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0206-7597","authenticated-orcid":false,"given":"Maria","family":"Garcia Quesada","sequence":"additional","affiliation":[{"name":"Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eunice","family":"Kagucia","sequence":"additional","affiliation":[{"name":"Epidemiology and Demography Department, KEMRI-Wellcome Trust Research Programme, Centre for Geographic Medicine-Coast, P.O. Box 230-80108, Kilifi, Kenya"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6562-2730","authenticated-orcid":false,"given":"Meagan","family":"Peterson","sequence":"additional","affiliation":[{"name":"Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Feikin","sequence":"additional","affiliation":[{"name":"Independent Consultant, 1296 Coppet, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Cohen","sequence":"additional","affiliation":[{"name":"World Health Organization, 1202 Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marissa","family":"Hetrich","sequence":"additional","affiliation":[{"name":"Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yangyupei","family":"Yang","sequence":"additional","affiliation":[{"name":"Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenna","family":"Sinkevitch","sequence":"additional","affiliation":[{"name":"Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krow","family":"Ampofo","sequence":"additional","affiliation":[{"name":"Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurie","family":"Aukes","sequence":"additional","affiliation":[{"name":"Vaccine Study Center, Kaiser Permanente, Oakland, CA 94612, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabrina","family":"Bacci","sequence":"additional","affiliation":[{"name":"European Centre for Disease Prevention and Control, 169 73 Solna, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Godfrey","family":"Bigogo","sequence":"additional","affiliation":[{"name":"Centre for Global Health Research, Kenya Medical Research Institute, P.O. Box 1578-40100, Kisumu, Kenya"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7254-9102","authenticated-orcid":false,"given":"Maria-Cristina","family":"Brandileone","sequence":"additional","affiliation":[{"name":"National Laboratory for Meningitis and Pneumococcal Infections, Center of Bacteriology, Institute Adolfo Lutz (IAL), S\u00e3o Paulo 01246-902, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8275-3484","authenticated-orcid":false,"given":"Michael","family":"Bruce","sequence":"additional","affiliation":[{"name":"Arctic Investigations Program, Division of Preparedness and Emerging Infections, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Anchorage, AK 99508, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romina","family":"Camilli","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Italian National Institute of Health (Istituto Superiore di Sanit\u00e0, ISS), 00161 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6396-7265","authenticated-orcid":false,"given":"Jes\u00fas","family":"Castilla","sequence":"additional","affiliation":[{"name":"CIBER Epidemiolog\u00eda y Salud P\u00fablica, (CIBERESP), 28029 Madrid, Spain"},{"name":"Instituto de Salud P\u00fablica de Navarra-IdiSNA, 31003 Pamplona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guanhao","family":"Chan","sequence":"additional","affiliation":[{"name":"Singapore Ministry of Health, Communicable Diseases Division, Singapore 308442, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grettel","family":"Chanto Chac\u00f3n","sequence":"additional","affiliation":[{"name":"Instituto Costarricense de Investigaci\u00f3n y Ense\u00f1anza en Nutrici\u00f3n y Salud, Tres R\u00edos, 30301 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Temple Street, D01 YC76 Dublin 1, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ron","family":"Dagan","sequence":"additional","affiliation":[{"name":"The Faculty of Health Sciences, Ben-Gurion University of the Negev, 8410501 Beer-Sheva, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kostas","family":"Danis","sequence":"additional","affiliation":[{"name":"Sant\u00e9 Publique France, the French National Public Health Agency, FR-94410 Saint Maurice, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"de Miguel","sequence":"additional","affiliation":[{"name":"Epidemiology Department, Direcci\u00f3n General de Salud P\u00fablica, 28009 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"De Wals","sequence":"additional","affiliation":[{"name":"Department of Social and Preventive Medicine, Laval University, Qu\u00e9bec, QC G1V 0A6, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefanie","family":"Desmet","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Immunology and Transplantation, KU Leuven, 3000 Leuven, Belgium"},{"name":"National Reference Centre for Streptococcus Pneumoniae, University Hospitals Leuven, 3000 Leuven, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yvonne","family":"Galloway","sequence":"additional","affiliation":[{"name":"Epidemiology Team, Institute of Environmental Science and Research, Porirua, Wellington 5022, New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theano","family":"Georgakopoulou","sequence":"additional","affiliation":[{"name":"National Public Health Organisation, 15123 Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Hammitt","sequence":"additional","affiliation":[{"name":"Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA"},{"name":"Epidemiology and Demography Department, KEMRI-Wellcome Trust Research Programme, Centre for Geographic Medicine-Coast, P.O. Box 230-80108, Kilifi, Kenya"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2418-6474","authenticated-orcid":false,"given":"Markus","family":"Hilty","sequence":"additional","affiliation":[{"name":"Swiss National Reference Centre for invasive Pneumococci, Institute for Infectious Diseases, University of Bern, 3012 Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8811-1308","authenticated-orcid":false,"given":"Pak-Leung","family":"Ho","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Carol Yu Centre for Infection, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay","family":"Jayasinghe","sequence":"additional","affiliation":[{"name":"National Centre for Immunisation Research and Surveillance and Discipline of Child and Adolescent Health, Children\u2019s Hospital Westmead Clinical School, Faculty of Medicine and Health, University of Sydney, Westmead, NSW 2145, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Kellner","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Calgary, and Alberta Health Services, Calgary, AB T3B 6A8, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7081-6273","authenticated-orcid":false,"given":"Jackie","family":"Kleynhans","sequence":"additional","affiliation":[{"name":"Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, Sandringham, Johannesburg 2192, South Africa"},{"name":"School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Braamfontein, Johannesburg 2000, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirjam","family":"Knol","sequence":"additional","affiliation":[{"name":"National Institute for Public Health and the Environment, 3721 MA Bilthoven, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jana","family":"Kozakova","sequence":"additional","affiliation":[{"name":"National Institute of Public Health (NIPH), 100 42 Praha, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl","family":"Kristinsson","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology, Landspitali-The National University Hospital, Hringbraut, 101 Reykjavik, Iceland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shamez","family":"Ladhani","sequence":"additional","affiliation":[{"name":"Immunisation and Countermeasures Division, Public Health England, London NW9 5EQ, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Lara","sequence":"additional","affiliation":[{"name":"Servicio de Bacteriolog\u00eda Cl\u00ednica, Departamento de Bacteriolog\u00eda, INEI-ANLIS \u201cDr. Carlos G. Malbr\u00e1n\u201d, Buenos Aires C1282 AFF, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Le\u00f3n","sequence":"additional","affiliation":[{"name":"Laboratorio Central de Salud P\u00fablica, Asunci\u00f3n, Paraguay (Central Laboratory of Public Health, Asunci\u00f3n, Paraguay), Asunci\u00f3n, Paraguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiia","family":"Lepp","sequence":"additional","affiliation":[{"name":"Department of Communicable Disease and Control and Health Protection, Public Health Agency of Sweden, 171 82 Solna, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grant","family":"Mackenzie","sequence":"additional","affiliation":[{"name":"Faculty of Infectious and Tropical Diseases, London School of Hygiene &amp; Tropical Medicine, Keppel St, London WC1E 7HT, UK"},{"name":"Medical Research Council Unit the Gambia at London School of Hygiene &amp; Tropical Medicine, P.O. Box 273, Banjul, The Gambia"},{"name":"New Vaccines Group, Murdoch Children\u2019s Research Institute, Parkville, Melbourne, VIC 3052, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8546-395X","authenticated-orcid":false,"given":"Lucia","family":"Mad\u2019arov\u00e1","sequence":"additional","affiliation":[{"name":"National Reference Centre for Pneumococcal and Haemophilus Diseases, Regional Authority of Public Health, 975 56 Bansk\u00e1 Bystrica, Slovakia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison","family":"McGeer","sequence":"additional","affiliation":[{"name":"Toronto Invasive Bacterial Diseases Network, and Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A8, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuya","family":"Mungun","sequence":"additional","affiliation":[{"name":"National Center of Communicable Diseases (NCCD), Ministry of Health, Bayanzurkh District, Ulaanbaatar 13336, Mongolia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason","family":"Mwenda","sequence":"additional","affiliation":[{"name":"World Health Organization Regional Office for Africa, P.O. Box 06, Brazzaville, Congo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Nuorti","sequence":"additional","affiliation":[{"name":"Department of Health Security, Finnish Institute for Health and Welfare, 00271 Helsinki, Finland"},{"name":"Health Sciences Unit, Faculty of Social Sciences, Tampere University, 33100 Tampere, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0971-2245","authenticated-orcid":false,"given":"N\u00e9h\u00e9mie","family":"Nzoyikorera","sequence":"additional","affiliation":[{"name":"Bacteriology-Virology and Hospital Hygiene Laboratory, Ibn Rochd University Hospital Centre, Casablanca 20250, Morocco"},{"name":"Department of Microbiology, Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, Casablanca 20000, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5919-7520","authenticated-orcid":false,"given":"Kazunori","family":"Oishi","sequence":"additional","affiliation":[{"name":"Toyama Institute of Health, Imizu, Toyama 939-0363, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia","family":"De Oliveira","sequence":"additional","affiliation":[{"name":"Pan American Health Organization, World Health Organization, Washington, DC 20037, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Metka","family":"Paragi","sequence":"additional","affiliation":[{"name":"Centre for Medical Microbiology, National Laboratory of Health, Environment and Food, 2000 Maribor, Slovenia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamara","family":"Pilishvili","sequence":"additional","affiliation":[{"name":"National Center for Immunizations and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8607-2467","authenticated-orcid":false,"given":"Rodrigo","family":"Puentes","sequence":"additional","affiliation":[{"name":"Instituto de Salud P\u00fablica de Chile, Santiago 7780050, Santiago Metropolitan, Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Rafai","sequence":"additional","affiliation":[{"name":"Ministry of Health and Medical Services, Suva, Fiji"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samir","family":"Saha","sequence":"additional","affiliation":[{"name":"Child Health Research Foundation, Dhaka 1207, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larisa","family":"Savrasova","sequence":"additional","affiliation":[{"name":"Centre for Disease Prevention and Control of Latvia, 1005 Riga, Latvia"},{"name":"Doctoral Studies Department, Riga Stradin\u0161 University, 1007 Riga, Latvia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camelia","family":"Savulescu","sequence":"additional","affiliation":[{"name":"Epidemiology Department, Epiconcept, 75012 Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Scott","sequence":"additional","affiliation":[{"name":"Epidemiology and Demography Department, KEMRI-Wellcome Trust Research Programme, Centre for Geographic Medicine-Coast, P.O. Box 230-80108, Kilifi, Kenya"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3338-9967","authenticated-orcid":false,"given":"Kevin","family":"Scott","sequence":"additional","affiliation":[{"name":"Bacterial Respiratory Infection Service, Scottish Microbiology Reference Laboratory, NHS GG&amp;C, Glasgow, G31 2ER, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatima","family":"Serhan","sequence":"additional","affiliation":[{"name":"World Health Organization, 1202 Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lena","family":"Setchanova","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Medical University of Sofia, Faculty of Medicine, 1431 Sofia, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadja","family":"Sinkovec Zorko","sequence":"additional","affiliation":[{"name":"Communicable Diseases Centre, National Institute of Public Health, 1000 Ljubljana, Slovenia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2247-830X","authenticated-orcid":false,"given":"Anna","family":"Skoczy\u0144ska","sequence":"additional","affiliation":[{"name":"National Reference Centre for Bacterial Meningitis, National Medicines Institute, 00-725 Warsaw, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5285-7039","authenticated-orcid":false,"given":"Todd","family":"Swarthout","sequence":"additional","affiliation":[{"name":"Malawi-Liverpool-Wellcome Trust Clinical Research Programme, P.O. Box 30096, Chichiri, Blantyre, Malawi"},{"name":"NIHR Global Health Research Unit on Mucosal Pathogens, Division of Infection and Immunity, UCL, Bloomsbury, London WC1E 6BT, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Palle","family":"Valentiner-Branth","sequence":"additional","affiliation":[{"name":"Infectious Disease Epidemiology and Prevention, Statens Serum Institut, DK-2300 Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"van der Linden","sequence":"additional","affiliation":[{"name":"National Reference Center for Streptococci, Department of Medical Microbiology, University Hospital RWTH Aachen, 52074 Aachen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didrik","family":"Vestrheim","sequence":"additional","affiliation":[{"name":"Department of Infection Control and Vaccine, Norwegian Institute of Public Health, 0456 Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0243-7455","authenticated-orcid":false,"given":"Anne","family":"von Gottberg","sequence":"additional","affiliation":[{"name":"Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, Sandringham, Johannesburg 2192, South Africa"},{"name":"School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Braamfontein, Johannesburg 2000, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8631-0020","authenticated-orcid":false,"given":"Inci","family":"Yildirim","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Yale New Haven Children\u2019s Hospital, New Haven, CT 06504, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9872-2313","authenticated-orcid":false,"given":"Kyla","family":"Hayford","sequence":"additional","affiliation":[{"name":"Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the PSERENADE Team","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,4,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e744","DOI":"10.1016\/S2214-109X(18)30247-X","article-title":"Burden of Streptococcus Pneumoniae and Haemophilus Influenzae Type b Disease in Children in the Era of Conjugate Vaccines: Global, Regional, and National Estimates for 2000\u201315","volume":"6","author":"Wahl","year":"2018","journal-title":"Lancet Glob. Health"},{"key":"ref_2","unstructured":"World Health Organization (2021, January 04). Pneumococcal Disease. Available online: https:\/\/www.who.int\/ith\/diseases\/pneumococcal\/en\/."},{"key":"ref_3","unstructured":"World Health Organization (2007). Pneumococcal Conjugate Vaccine for Childhood Immunization\u2014WHO Position Paper. Wkly. Epidemiol. Rec., 82, 93\u2013104."},{"key":"ref_4","unstructured":"World Health Organization (2019). Pneumococcal Conjugate Vaccines in Infants and Children under 5 Years of Age: WHO Position Paper. Wkly. Epidemiol. Rec., 94, 85\u2013104."},{"key":"ref_5","unstructured":"(2020, December 29). International Vaccine Access Center (IVAC), Johns Hopkins Bloomberg School of Public Health VIEW-Hub. Available online: https:\/\/view-hub.org."},{"key":"ref_6","unstructured":"World Health Organization (2021, January 05). Invasive Bacterial Vaccine Preventable Diseases Laboratory Network. 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