{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T07:44:20Z","timestamp":1772005460606,"version":"3.50.1"},"reference-count":56,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2021,6,4]],"date-time":"2021-06-04T00:00:00Z","timestamp":1622764800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microorganisms"],"abstract":"<jats:p>Neurocysticercosis (NCC), a leading global cause of severe progressive headache and epilepsy, in developed or affluent countries is mostly diagnosed among immigrants from poor or developing Taenia solium taeniasis-endemic countries. Taeniasis carriers in Kuwait are routinely screened by insensitive stool microscopy. In this study, enzyme-linked immunoelectrotransfer blot (EITB) was used as a confirmatory test for NCC. Screening was performed on 970 patients referred for suspected NCC on the basis of relevant history and\/or ring-enhancing lesions on computed tomography and\/or magnetic resonance imaging during a 14-year period in Kuwait. Demographic data and clinical details were retrieved from laboratory or hospital records. EITB was positive in 150 subjects (15.5%), including 98 expatriates mostly originating from taeniasis-endemic countries and, surprisingly, 52 Kuwaiti nationals. The clinical details of 48 of 50 NCC cases diagnosed during 2014\u20132019 were available. Most common symptoms included seizures, persistent headache with\/without fever, and fits or loss of consciousness. Cysticercal lesions were located at various brain regions in 39 of 48 patients. Multiple members of 3 families with NCC were identified; infection was linked to domestic workers from taeniasis-endemic countries and confirmed in at least 1 family. Our data show that NCC is predominantly imported in Kuwait by expatriates originating from taeniasis-endemic countries who transmit the infection to Kuwaiti citizens.<\/jats:p>","DOI":"10.3390\/microorganisms9061221","type":"journal-article","created":{"date-parts":[[2021,6,4]],"date-time":"2021-06-04T11:12:13Z","timestamp":1622805133000},"page":"1221","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["A Large Case Series of Neurocysticercosis in Kuwait, a Nonendemic Arabian Gulf Country in the Middle East Region"],"prefix":"10.3390","volume":"9","author":[{"given":"Jamshaid","family":"Iqbal","sequence":"first","affiliation":[{"name":"Department of Microbiology, Faculty of Medicine, Kuwait University, P. O. Box 24923, Safat 13110, Kuwait"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3492-4781","authenticated-orcid":false,"given":"Suhail","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Faculty of Medicine, Kuwait University, P. O. Box 24923, Safat 13110, Kuwait"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"Al-Awadhi","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Faculty of Medicine, Kuwait University, P. O. Box 24923, Safat 13110, Kuwait"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir","family":"Masud","sequence":"additional","affiliation":[{"name":"Al-Sabah Hospital, Ministry of Health, Kuwait City 13001, Kuwait"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zainab","family":"Mohsin","sequence":"additional","affiliation":[{"name":"Farwaniya Hospital, Ministry of Health, Farwaniya 81004, Kuwait"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdullah Y.","family":"Abdulrasoul","sequence":"additional","affiliation":[{"name":"Jahra Hospital, Ministry of Health, Alsafat 01753, Kuwait"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khalifa","family":"Albenwan","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Faculty of Medicine, Kuwait University, P. O. Box 24923, Safat 13110, Kuwait"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadia","family":"Alenezi","sequence":"additional","affiliation":[{"name":"Parasitology Reference Laboratory, Mubarak Al-Kabir Hospital, Jabriya 47060, Kuwait"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatima","family":"AlFarsi","sequence":"additional","affiliation":[{"name":"Parasitology Reference Laboratory, Mubarak Al-Kabir Hospital, Jabriya 47060, Kuwait"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,6,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1016\/S1474-4422(14)70094-8","article-title":"Clinical symptoms, diagnosis, and treatment of neurocysticercosis","volume":"13","author":"Garcia","year":"2014","journal-title":"Lancet Neurol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.meegid.2015.06.022","article-title":"Recent advances and perspectives in molecular epidemiology of Taenia solium cysticercosis","volume":"40","author":"Ito","year":"2016","journal-title":"Infect. 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