{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T03:54:43Z","timestamp":1793073283508,"version":"4.5.0"},"reference-count":41,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2021,6,5]],"date-time":"2021-06-05T00:00:00Z","timestamp":1622851200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microorganisms"],"abstract":"<jats:p>Solobacterium moorei is an anaerobic Gram-positive bacillus present within the oral and the intestinal microbiota that has rarely been described in human infections. Besides its role in halitosis and oral infections, S. moorei is considered to be an opportunistic pathogen causing mainly bloodstream and surgical wound infections. We performed a retrospective study of 27 cases of infections involving S. moorei in two French university hospitals between 2006 and 2021 with the aim of increasing our knowledge of this unrecognized opportunistic pathogen. We also reviewed all the data available in the literature and in genetic and metagenomic sequence databases. In addition to previously reported infections, S. moorei had been isolated from various sites and involved in intra-abdominal, osteoarticular, and cerebral infections more rarely or not previously reported. Although mostly involved in polymicrobial infections, in seven cases, it was the only pathogen recovered. Not included in all mass spectrometry databases, its identification can require 16S rRNA gene sequencing. High susceptibility to antibiotics (apart from rifampicin, moxifloxacin, and clindamycin; 91.3%, 11.8%, and 4.3% of resistant strains, respectively) has been noted. Our global search strategy revealed S. moorei to be human-associated, widely distributed in the human microbiota, including the vaginal and skin microbiota, which may be other sources for infection in addition to the oral and gut microbiota.<\/jats:p>","DOI":"10.3390\/microorganisms9061229","type":"journal-article","created":{"date-parts":[[2021,6,6]],"date-time":"2021-06-06T23:59:55Z","timestamp":1623023995000},"page":"1229","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["A New Look at the Genus Solobacterium: A Retrospective Analysis of Twenty-Seven Cases of Infection Involving S. moorei and a Review of Sequence Databases and the Literature"],"prefix":"10.3390","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7953-4870","authenticated-orcid":false,"given":"Corentine","family":"Alauzet","sequence":"first","affiliation":[{"name":"Laboratoire SIMPA Stress Immunit\u00e9 Pathog\u00e8nes EA 7300, Universit\u00e9 de Lorraine, & Service de Microbiologie, CHRU de Nancy, 54500 Vand\u0153uvre-l\u00e8s-Nancy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabien","family":"Aujoulat","sequence":"additional","affiliation":[{"name":"HydroSciences Montpellier, CNRS, IRD, Universit\u00e9 de Montpellier, 34093 Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Lozniewski","sequence":"additional","affiliation":[{"name":"Laboratoire SIMPA Stress Immunit\u00e9 Pathog\u00e8nes EA 7300, Universit\u00e9 de Lorraine, & Service de Microbiologie, CHRU de Nancy, 54500 Vand\u0153uvre-l\u00e8s-Nancy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Safa","family":"Ben Brahim","sequence":"additional","affiliation":[{"name":"Service de Microbiologie, CHRU de Nancy, 54500 Vand\u0153uvre-l\u00e8s-Nancy, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chlo\u00e9","family":"Domenjod","sequence":"additional","affiliation":[{"name":"Service de Microbiologie et Hygi\u00e8ne Hospitali\u00e8re, CHU de N\u00eemes, 30029 N\u00eemes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3840-5527","authenticated-orcid":false,"given":"C\u00e9cilia","family":"Enault","sequence":"additional","affiliation":[{"name":"Service de Microbiologie et Hygi\u00e8ne Hospitali\u00e8re, CHU de N\u00eemes, 30029 N\u00eemes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9484-0304","authenticated-orcid":false,"given":"Jean-Philippe","family":"Lavigne","sequence":"additional","affiliation":[{"name":"VBIC, INSERM U1047, Universit\u00e9 de Montpellier, Service de Microbiologie et Hygi\u00e8ne Hospitali\u00e8re, CHU N\u00eemes, 30029 N\u00eemes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2130-6335","authenticated-orcid":false,"given":"H\u00e9l\u00e8ne","family":"Marchandin","sequence":"additional","affiliation":[{"name":"HydroSciences Montpellier, CNRS, IRD, Universit\u00e9 de Montpellier, Service de Microbiologie et Hygi\u00e8ne Hospitali\u00e8re, CHU de N\u00eemes, 30029 N\u00eemes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,6,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1111\/j.1348-0421.2000.tb02487.x","article-title":"Phylogenic and phenotypic characterization of some Eubacterium-like isolates from human feces: Description of Solobacterium moorei Gen. 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