{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,22]],"date-time":"2025-11-22T18:44:19Z","timestamp":1763837059285,"version":"build-2065373602"},"reference-count":21,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2009,1,15]],"date-time":"2009-01-15T00:00:00Z","timestamp":1231977600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>A fast, general, environmentally friendly and facile method for preparation of five- and six-membered ring diazaheterocylic salts under microwave irradiation is presented. The N-alkylation reactions of imidazole, pyrimidine, pyridazine and phthalazine have been studied. The microwaves remarkably accelerated these N-alkylations, the reaction times decreased dramatically, the reaction conditions were milder, the consumed energy decreased considerably and the amount of solvents used was reduced substantially. Consequently, the microwave assisted alkylation of N-containing heterocycles could be considered eco-friendly. In some cases, under MW irradiation the yields are also higher. A comparative study of microwave vs. classical conditions (liquid solvents) has been done. Twelve new diazaheterocylic salts of potential practical interest were obtained.<\/jats:p>","DOI":"10.3390\/molecules14010403","type":"journal-article","created":{"date-parts":[[2009,1,15]],"date-time":"2009-01-15T05:21:48Z","timestamp":1231996908000},"page":"403-411","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Microwave Assisted Reactions of Some Azaheterocylic Compounds"],"prefix":"10.3390","volume":"14","author":[{"given":"Gheorghita","family":"Zbancioc","sequence":"first","affiliation":[{"name":"\u201cAl. I. Cuza\u201d University of Iasi, Organic Chemistry Department, Bd. Carol 11, 700506 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasilichia","family":"Bejan","sequence":"additional","affiliation":[{"name":"\u201cAl. I. Cuza\u201d University of Iasi, Organic Chemistry Department, Bd. 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