{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T20:58:44Z","timestamp":1791147524480,"version":"4.1.0"},"reference-count":28,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2009,1,19]],"date-time":"2009-01-19T00:00:00Z","timestamp":1232323200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>Solvent-free synthesis of pyrano[2,3-d]pyrimidine-2,4(1H,3H)-diones by ball-milling and without any catalyst is described. This method provides several advantages such as being environmentally friendly, using a simple workup procedure, and affording high yields.<\/jats:p>","DOI":"10.3390\/molecules14010474","type":"journal-article","created":{"date-parts":[[2009,1,19]],"date-time":"2009-01-19T08:47:20Z","timestamp":1232354840000},"page":"474-479","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":102,"title":["Mechanochemical Solvent-Free and Catalyst-Free One-Pot Synthesis of Pyrano[2,3-d]Pyrimidine-2,4(1H,3H)-Diones with Quantitative Yields"],"prefix":"10.3390","volume":"14","author":[{"given":"Sara","family":"Mashkouri","sequence":"first","affiliation":[{"name":"Organic Chemistry Research Laboratory, Department of Chemistry, Iran University of Science and Technology, 16846 Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9501-3028","authenticated-orcid":false,"given":"M.","family":"Reza Naimi-Jamal","sequence":"additional","affiliation":[{"name":"Organic Chemistry Research Laboratory, Department of Chemistry, Iran University of Science and Technology, 16846 Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2009,1,19]]},"reference":[{"key":"ref_1","first-page":"231","article-title":"Effect of compounds on a spectrum of rat tumors","volume":"3","author":"Suguira","year":"1973","journal-title":"Cancer Chemother. 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