{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T09:39:12Z","timestamp":1769161152712,"version":"3.49.0"},"reference-count":37,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2010,4,27]],"date-time":"2010-04-27T00:00:00Z","timestamp":1272326400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecules"],"abstract":"<jats:p>A series of fluorescent sensors based on 8-hydroxyquinoline dansylate as core and dendritic PAMAM as shell were synthesized. Their fluorescence characteristic and fluorescent sensing behavior toward metal ions were studied in water\/methanol (1: 1, v\/v). The sensors exhibit good selectivity and sensitivity for Fe3+ ion and to some extent for Cr3+ ion. The third generation dendrimer has the better sensitivity than the first and second generations.<\/jats:p>","DOI":"10.3390\/molecules15052962","type":"journal-article","created":{"date-parts":[[2010,4,27]],"date-time":"2010-04-27T11:18:19Z","timestamp":1272367099000},"page":"2962-2971","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["8-Hydroxyquinoline Dansylates Modified with PAMAM Dendrimer as Fluorescent Fe3+ Sensors"],"prefix":"10.3390","volume":"15","author":[{"given":"Qi","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Chemistry, The Key Laboratory of Bioorganic Phosphorous Chemistry and Chemical Biology, Tsinghua University, Beijing 100084, China"},{"name":"School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaowu","family":"Sha","sequence":"additional","affiliation":[{"name":"Department of Chemistry, The Key Laboratory of Bioorganic Phosphorous Chemistry and Chemical Biology, Tsinghua University, Beijing 100084, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin-Hui","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2010,4,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/3-540-46577-4_3","article-title":"Host-guest chemistry of dendritic molecules","volume":"210","author":"Baars","year":"2000","journal-title":"Top. Curr. Chem."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/S0079-6700(00)00011-3","article-title":"Functional dendrimers, hyperbranched and star polymers","volume":"25","author":"Inoue","year":"2000","journal-title":"Prog. Polym. Sci."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.polymer.2007.10.021","article-title":"Poly(amidoamine), polypropylenimine, and related dendrimers and dendrons possessing different 1\u21922 branching motifs: An overview of the divergent procedures","volume":"49","author":"Newkome","year":"2008","journal-title":"Polymer"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/S1359-6446(01)01757-3","article-title":"Poly(amidoamine) (PAMAM) dendrimers: From biomimicry to drug delivery and biomedical applications","volume":"6","author":"Esfand","year":"2001","journal-title":"Drug Discov. Today"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0168-3659(99)00245-X","article-title":"Water-soluble dendritic unimolecular micelles: Their potential as drug delivery agents","volume":"65","author":"Liu","year":"2000","journal-title":"J. Control. Release"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0921-5093(98)01096-X","article-title":"Preparation of Water-soluble dendritic unimolecular micelles as potential drug delivery agents","volume":"80","author":"Liu","year":"1999","journal-title":"Polym. Mater. Sci. Eng."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1743","DOI":"10.1016\/S0040-4039(98)02680-X","article-title":"The Synthesis of water soluble dendrimers, and their application as possible drug delivery systems","volume":"40","author":"Twyman","year":"1999","journal-title":"Tetrahedron Lett."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/S1367-5931(00)00227-1","article-title":"Polymers in drug delivery","volume":"5","author":"Pillai","year":"2001","journal-title":"Curr. Opin. Chem. Biol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/S1461-5347(99)00203-5","article-title":"Designing dendrimers for drug delivery","volume":"2","author":"Liu","year":"1999","journal-title":"Pharm. Sci. Tech. Today"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1002\/(SICI)1521-3765(19980807)4:8<1353::AID-CHEM1353>3.0.CO;2-0","article-title":"Functional Dendrimers: Unique Biological Mimics","volume":"4","author":"Smith","year":"1998","journal-title":"Chem. Eur. J."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1021\/cr970069y","article-title":"About dendrimers: Structure, physical properties, and applications","volume":"99","author":"Bosman","year":"1999","journal-title":"Chem. Rev."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0143-7208(00)00099-1","article-title":"Dendrimers and dyes-a review","volume":"48","author":"Froehling","year":"2001","journal-title":"Dyes Pigments"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"8101","DOI":"10.1021\/ja010579g","article-title":"Polyphenylene dendrimers with different fluorescent chromophores asymmetrically distributed at the periphery","volume":"123","author":"Weil","year":"2001","journal-title":"J. Am. Chem. Soc."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"7474","DOI":"10.1021\/jo990776m","article-title":"Modular Approach to the accelerated convergent growth of laser dye-labeled poly(aryl ether) dendrimers using a novel hypermonomer","volume":"64","author":"Gilat","year":"1999","journal-title":"JOrg. Chem."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.1002\/(SICI)1521-3773(19990517)38:10<1422::AID-ANIE1422>3.0.CO;2-V","article-title":"Light harvesting and energy transfer in novel convergently constructed dendrimers","volume":"38","author":"Gilat","year":"1999","journal-title":"Angew. Chem. Int. Ed."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1039\/b005993p","article-title":"Light-harvesting dendrimers","volume":"18","author":"Adronov","year":"2000","journal-title":"Chem. Commun."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"4912","DOI":"10.1021\/ja990387+","article-title":"Photoresponsive azobenzene-containing dendrimers with multiple discrete states","volume":"121","author":"Jungle","year":"1999","journal-title":"J. Am. Chem. Soc."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"3551","DOI":"10.1016\/S0032-3861(97)10003-9","article-title":"Polymers from coumarines: 4. Design and synthesis of novel hyperbranched and comb-like coumarin-containing polymers","volume":"39","author":"Fomie","year":"1998","journal-title":"Polymer"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1039\/b106813j","article-title":"Photochemical and photophysical properties of poly(propylene amine) dendrimers with peripheral naphthalene and azobenzene groups","volume":"1","author":"Vogtle","year":"2002","journal-title":"Photochem. Photobiol. Sci."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1039\/b002116o","article-title":"Dendrimers as fluorescent sensors with signal amplification","volume":"10","author":"Balzani","year":"2000","journal-title":"Chem. Commun."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"3765","DOI":"10.1039\/b003214j","article-title":"Effect of protons and metal ions on the fluorescence properties of a polylysin dendrimer containing twenty four dansyl units","volume":"21","author":"Balzani","year":"2000","journal-title":"J. Chem. Soc. Dalton Trans."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"8281","DOI":"10.1021\/ja980619p","article-title":"Dendritic nucleic acid probes for DNA biosensors","volume":"120","author":"Wang","year":"1998","journal-title":"J. Am. Chem. Soc."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1021\/ac000460a","article-title":"Enhanced detection of live bacteria using a dendrimer thin film in an optical biosensor","volume":"73","author":"Chang","year":"2001","journal-title":"Anal. Chem."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"7478","DOI":"10.1021\/ma8008228","article-title":"Synthesis and Photophysical properties of poly(ester-amine) dendrimers with focal 4-amino-N-benzylphthalimide, as Sensitive media probes and switchable proton sensors","volume":"41","author":"Shi","year":"2008","journal-title":"Macromolecules"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"922","DOI":"10.3390\/molecules13040922","article-title":"Selective dendritic fluorescent sensors for Zn(II)","volume":"13","author":"Wang","year":"2008","journal-title":"Molecules"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"3961","DOI":"10.1016\/j.tetlet.2004.03.106","article-title":"Synthesis of fluorescent dendritic 8-hydroxyquinoline ligands and investigation on their coordinated Zn(II) complexes","volume":"45","author":"Shen","year":"2004","journal-title":"Tetrahedron Lett."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"9417","DOI":"10.1016\/S0040-4039(02)02329-8","article-title":"A divergent synthesis of new aliphatic poly(ester-amine) dendrimers bearing peripheral hydroxyl or acrylate groups","volume":"43","author":"Sha","year":"2002","journal-title":"Tetrahedron Lett."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1016\/j.tetlet.2006.12.138","article-title":"Synthesis, structural characterization, and \ufb02uorescent chemosensory properties of novel molecular clips based on diethoxycarbonyl glycoluril","volume":"48","author":"Hu","year":"2007","journal-title":"Tetrahedron Lett."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"13522","DOI":"10.1021\/ja050652t","article-title":"On the development of sensor molecules that display Fe(III)-amplified fluorescence","volume":"127","author":"Bricks","year":"2005","journal-title":"J. Am. Chem. Soc."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1016\/j.bmc.2004.11.053","article-title":"A new route to trihydroxamate-containing artificial siderophores and synthesis of a new fluorescent probe","volume":"13","author":"Ouchetto","year":"2005","journal-title":"Bioorg. Med. Chem."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"11293","DOI":"10.1016\/j.tet.2004.07.053","article-title":"Selective metal ion recognition using a \ufb02uorescent 1,8-diquinolylnaphthalene-derived sensor in aqueous solution","volume":"60","author":"Tumambac","year":"2004","journal-title":"Tetrahedron"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"6349","DOI":"10.1021\/jm049751s","article-title":"Design, synthesis, physicochemical properties, and evaluation of novel iron chelators with fluorescent sensors","volume":"47","author":"Ma","year":"2004","journal-title":"J. Med. Chem."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1021\/jm970581b","article-title":"Modular fluorescent-labeled siderophore analogues","volume":"41","author":"Nudelman","year":"1998","journal-title":"J. Med. Chem."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"12368","DOI":"10.1021\/ja9610646","article-title":"Fluorescently-labeled ferrichrome analogs as probes for receptor-mediated, microbial iron uptake","volume":"118","author":"Weizman","year":"1996","journal-title":"J. Am. Chem. Soc."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.3390\/12051191","article-title":"Synthesis of 5-dialkyl(aryl)aminomethyl-8-hydroxyquinoline dansylates as selectivefluorescent sensors of Fe3+","volume":"12","author":"Peng","year":"2007","journal-title":"Molecules"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.synthmet.2004.05.004","article-title":"Novel red-light emitting metal complex based on asymmetric perylene bisimide and 8-hydroxyquinoline dyads","volume":"145","author":"Fan","year":"2004","journal-title":"Synth. Met."},{"key":"ref_37","first-page":"113","article-title":"Studies on the formation of complex minerals in solution and on their stability","volume":"9","author":"Job","year":"1928","journal-title":"Ann. Chim."}],"container-title":["Molecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1420-3049\/15\/5\/2962\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T22:02:15Z","timestamp":1760220135000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1420-3049\/15\/5\/2962"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,4,27]]},"references-count":37,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2010,5]]}},"alternative-id":["15052962"],"URL":"https:\/\/doi.org\/10.3390\/molecules15052962","relation":{},"ISSN":["1420-3049"],"issn-type":[{"value":"1420-3049","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,4,27]]}}}